Dr. Howard and Wendy open with a rare sliver of relief: Guinea-Bissau halting an ethically alarming Hepatitis B vaccine trial proposal framed as a "natural experiment" on infants. From there, the episode pivots into the broader breakdown: vaccine leadership rhetoric that treats polio as negotiable and measles as a "real-world learning opportunity," the normalization of losing measles elimination status, and growing fears that autism-focused federal committees are being reshaped to fit a predetermined vaccine agenda.

They connect these developments to institutional erosion—NIH advisory panels hollowing out, FDA messages disappearing (including warnings about dangerous "autism cures"), and industry pullback as vaccine trials become politically radioactive. The closing argument is blunt: many of the loudest COVID contrarian voices warned about authoritarian overreach in theory, then aligned with (or enabled) the actual power structures now degrading public health in practice—and the hosts insist the record needs to be preserved so this moment can't be memory-holed later.

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