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In this episode, Ana Reisdorf (Registered Dietitian and GLP-1 user) sits down with Laraine and Christopher from The Downsized to unpack what happens when GLP-1s change more than the scale. They share their combined 150+ lb loss, what maintenance really looks like (including dose decisions), and the mental shift of unlearning decades of “diet brain.”

You’ll hear the unfiltered realities: food noise returning when dosing changes, side effects that can be unpredictable, access anxiety, and the non-scale victories that matter most - less inflammation, less pain, and getting your life back. They also cover what their audience asks every day: plateaus, fear of the first shot, “what do I eat?”, and how to advocate for yourself when you’re not getting enough guidance.

More About Laraine and Christopher:

Christopher and Laraine Durham are the husband-and-wife team behind The Downsized, a daily YouTube channel for people who want honest, real-world conversations about GLP-1 medications and the medical treatment of obesity.

They have been married for 22 years and live in Charlotte, North Carolina, with their three kids. Together, they have lost more than 150 pounds using GLP-1 therapies, including tirzepatide (Mounjaro) and Zepbound. They started this channel in September 2023 after realizing how confusing, lonely, and overwhelming this process can feel.

The Downsized website: https://thedownsized.org/

The Downsized Youtube Channel: https://www.youtube.com/@thedownsized

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*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.