ABNORMAL Normal Saline
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ABNORMAL Normal Saline
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Welcome to Season 2
0.9% “Normal” Saline is one of the most commonly prescribed intravenous fluids in medicine, yet its name is one of the great misnomers of clinical practice.
In this episode, The Clinical Etymologist traces the laboratory origins of 0.9% sodium chloride and explains why it was never designed to replicate human plasma.
Through bedside teaching and clinical physiology, we explore how excess chloride alters acid–base balance and renal function.
The episode examines key evidence demonstrating the unintended potential harms of routine saline use and clarifies when “abnormal” normal saline is exactly the right choice—and when it is not.
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