In this episode, Mark Papermaster sits down with Leigh-Ann Russell, CIO & Global Head of Engineering at BNY, to discuss how one of the world’s most systemically important banks is operationalizing AI with trust at global scale. They unpack how data becomes a strategic asset, the shift from pilots to production, the rise of agentic AI for operations and client experience, building a culture for zero-downtime systems, and balancing innovation with regulation and risk. From the world’s largest custodian bank safeguarding $56T+ in assets to modernizing platforms across 35 countries, learn how BNY is reimagining finance with resilient, responsible AI.

In this episode of Advanced Insights, AMD CTO Mark Papermaster sits down with Anush Elangovan, CVP of AI Software at AMD, to discuss how the company is building an open, developer-first AI software ecosystem. They unpack the journey behind ROCm 7, performance breakthroughs, expanded model support, and why open source innovation is critical for energy-efficient, scalable AI infrastructure. From hyperscaler deployments to enabling inference across cloud and edge, learn how AMD is shaping a more open and accessible AI future.

Scott Crowder, VP of IBM Quantum Adoption, joins Mark Papermaster to explore how quantum computing is moving from research labs toward practical deployment. From hybrid quantum-classical systems that accelerate discovery, to breakthroughs in algorithms, error correction, and scaling, this episode unpacks the roadmap to quantum advantage. They also discuss the critical role of open ecosystems, HPC integration, and the AMD and IBM partnership in advancing the next frontier of computing.00:00 Advanced Insights Overview00:31 Introduction & Welcome, Scott01:06 Quantum Computing Revolution02:33 Qubit: The Fundamental Unit of Quantum Computers 03:56 Classical vs. Quantum Algorithms 06:23 Quantum in Practice 07:22 Achieving Fault Tolerance 09:29 Where Are We on the Quantum Journey? 11:18 Integrating Classic and Quantum Computing 14:33 From the CPU to the GPU, to the QPU Accelerator 16:04 AMD and IBM Deliver Open Heterogeneous Systems 17:59 Open Ecosystem’s Role in Accelerating Innovation21:27 Outlook on Quantum Models for On-prem and Cloud23:43 Infrastructure that Enables IBM Quantum Computation Centers25:30 Transformational Quantum Computing is On the Horizon28:24 Thank You, Scott29:19 Takeaways30:10 Where to Watch and Closing***Subscribe: https://bit.ly/Subscribe_to_AMD Join the AMD Red Team Discord Server: https://discord.gg/amd-gamingLike us on Facebook: https://bit.ly/AMD_on_FacebookFollow us on Twitter: https://bit.ly/AMD_On_Twitter Follow us on Twitch: https://Twitch.tv/AMD Follow us on LinkedIn: https://bit.ly/AMD_on_Linkedin Follow us on Instagram: https://bit.ly/AMD_on_Instagram©2025 Advanced Micro Devices, Inc. AMD, the AMD Arrow Logo, and combinations thereof are trademarks of Advanced Micro Devices, Inc. in the United States and other jurisdictions. Other names are for informational purposes only and may be trademarks of their respective owners.

Pavan Davuluri, CVP for Windows and Silicon & Systems Integration at Microsoft, joins Mark Papermaster to unpack how Copilot+ PCs are reshaping Windows from the silicon up. From hybrid cloud-to-edge intelligence and on-device NPUs to privacy, latency, and energy efficiency, this episode explores the future of AI-powered PC experiences—and the AMD-Microsoft partnership behind it all.

00:00 Advanced Insights Overview

00:10 Introduction & Welcome, Pavan Davuluri

00:53 Computing Industry Trends

02:28 Mission of Copilot+ PCs

05:05 New Ryzen-based PCs

07:45 How Microsoft Adapts to Evolving AI Experience Requirements

11:45 AI PC Experience Has Potential to Realize Incredible Productivity Gains

16:06 Seamless Integration Across Edge and Cloud AI Compute for Optimal Model Interactions

20:13 Full-stack Investments for Simple, Secure, and Powerful Solutions

24:40 Developer-first Approach to AI PC Ecosystems

28:24 Future of Windows AI Experiences

31:10 Thank You, Pavan

31:35 Summary & Inflection Point

32:15 Where to Watch

Chris Gandolfo, EVP of OCI and AI Sales at Oracle, and Mark Papermaster explore what it really takes to train and deploy large language models at scale. From evolving compute needs and energy efficiency to the rise of inference, this episode dives deep into the future of enterprise AI infrastructure.

Sean McClain, Founder and CEO of Absci, and Mark Papermaster step into the world of drug discovery, where processes are incredibly time consuming, costly and complex.

Dan Rabinovitsj, VP of Infrastructure at Meta, and Mark Papermaster explore the amount of processing power it takes to enable the 3.2 billion people who connect daily on Facebook, Instagram and WhatsApp.

Brad McCredie, SVP of AMD’s Data Center GPU and Accelerated Processing business, and Mark Papermaster delve into the world of Exascale supercomputing and AMD’s journey to powering the top two supercomputers in the world. They also discuss the future of high-performance computing and AI.00:00 - 00:17 Series Overview 00:18 - 00:33 On This Episode Description 00:34 - 02:11 Intro to Guest Dr. Bradley McCredie 02:12 - 02:58 What it Takes to Build a Supercomputer 02:59 - 05:36 Early Lessons Learned at IBM 05:37 - 07:22 AMD Journey to Exascale 07:23 - 08:27 Frontier Supercomputer at Oakridge National Laboratory 08:28 - 09:12 Frontier Achieves 1.1 Exaflops…and Beyond 09:13 - 10:15 El Capitan at Lawrence Livermore National Labs 10:16 - 11:40 AI and HPC Technical Convergence 11:41 - 13:04 How Many Chiplets Does it Take? 13:05 - 13:34 Shared Memory Benefits 13:35 - 15:15 One Size Does Not Fit All, Flexibility for AI 15:16 - 16:53 Delivering Efficiency with Chiplets 16:54 - 19:33 Separate Machines for HPC and AI? 19:34 - 23:16 Driving the Future with Scale and Efficiency 23:17 - 23:42 Recapping the Main Takeaways 23:43 - 24:24 Series Closing ***Subscribe: https://bit.ly/Subscribe_to_AMD Join the AMD Red Team Community: https://www.amd.com/en/gaming/community Join the AMD Red Team Discord Server: https://discord.gg/amd-red-teamLike us on Facebook: https://bit.ly/AMD_on_FacebookFollow us on Twitter: https://bit.ly/AMD_On_Twitter Follow us on Twitch: https://Twitch.tv/AMD Follow us on LinkedIn: https://bit.ly/AMD_on_Linkedin Follow us on Instagram: https://bit.ly/AMD_on_Instagram©2025 Advanced Micro Devices, Inc. AMD, the AMD Arrow Logo, and combinations thereof are trademarks of Advanced Micro Devices, Inc. in the United States and other jurisdictions. Other names are for informational purposes only and may be trademarks of their respective owners.