Biotech company Imugene reported its half-year results yesterday. It’s still loss-making, but sharply cutting costs and seeing what appear to be genuinely encouraging clinical results.

Its lead cancer therapy, azer-cel, is showing strong response rates in difficult lymphoma cases, with some patients cancer-free for nearly two years - and the FDA has given positive feedback on the company’s strategy.

But at the same time, the company’s share price is down around 80pc over the last year.

Sean Aylmer speaks to Leslie Chong, CEO and Managing Director of Imugene, about what it takes to run a long-cycle biotech business, trying to develop life-changing treatments while keeping investors engaged.

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Australia has a productivity problem, and AI is often pitched as the solution. But while companies are running pilots everywhere, very few are actually getting AI into enterprise production.

Sean Aylmer speaks with Frank Fillmann, Executive Vice President and general manager of Salesforce ANZ, about why 95% of AI pilots fail, why the “last mile” is so hard, and how businesses can move from slick demos to real P&L impact.
Frank will be appearing today at Agentforce World Tour Sydney.

Fear & Greed is proud to partner with Salesforce for this event at the ICC. Over the next couple of weeks, we'll bring you a series of interviews exploring how agentic AI is transforming Aussie businesses. Visit https://www.salesforce.com/au/news/ for more information.

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US tech giants are spending as much as US$700 billion this year on AI — roughly a third of Australia’s GDP. But what if the profits and productivity gains take far longer to arrive than markets expect?

Sean Aylmer speaks with Dr Kevin Hebner, Global Investment Strategist at Epoch Investment Partners about the risks of over-concentration in US tech, the 'March of the Nines' and why every major technology wave in history has taken decades — not years — to deliver real returns.

This is general information only, and you should seek advice tailored to your circumstances before making investment decisions.

Find out more: https://fearandgreed.com.au/

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