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Behind the Breakthroughs

Behind the Breakthroughs

Written by: Inside Precision Medicine
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Join host Jonathan D. Grinstein, PhD, North American Editor for Inside Precision Medicine, as he uncovers the stories behind the pioneers driving the precision medicine revolution. Behind the Breakthroughs features candid interviews with seasoned veterans and rising stars, exploring their origin stories and groundbreaking contributions advancing the frontiers of patient diagnosis, treatment, and care.


In every episode, Jonathan goes beyond the science, diving deep into the personal and professional journeys of those striving to make these incredible new therapies more equitable and accessible globally. You'll discover how emerging technologies in molecular diagnostics, next-generation sequencing, genetic medicines (e.g., cell and gene therapies), and AI/ML are transforming treatment and bringing precision medicine closer to the forefront of healthcare. Whether you’re a researcher at a large pharma company or small biotech startup, a clinician at a major health system or community setting, a laboratory technician in the clinic or academia, an investor at a premier or venture capital firm, or just interested in the latest in medicine and healthcare, these interviews will inspire and inform you about personalized medicine's future.

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Episodes
  • Boyang Wang: Organ Swaps and Mass Preventative Gene Therapy to Extend Lifespan

    Boyang Wang: Organ Swaps and Mass Preventative Gene Therapy to Extend Lifespan
    Jan 7 2026
    Geroscience sits between hype and skepticism, with headlines swinging from dubious mouse-life supplements to ethically distant fantasies like organ or head transplants. Yet precision medicine has been turning science fiction into reality. Today’s guest, Boyang Wang, thinks lifespan extension is next. Founder of Singapore-based Immortal Dragons, he backs longevity companies—from organ printing to preventive gene therapies. A former computer scientist and tech entrepreneur, Wang now runs a $40M fund supporting underfunded bets on healthspan and aging.

    Hosted on Acast. See acast.com/privacy for more information.
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    54 mins
  • Year In Review: My Personal Genomics Journey Redux

    Year In Review: My Personal Genomics Journey Redux
    Dec 17 2025

    In this episode, I’m joined by Kevin Davies, PhD, Director of Professional Media Content Development at Sage Publications and acclaimed author of Editing Humanity, one of Jennifer Doudna’s favorite books on CRISPR. We explore key themes in precision medicine in 2025, including personal genomics, gene editing, and clinical impact. The discussion centers on my personal genomic testing series, major gene-editing advances, and emerging debates around embryo selection and IVF-based genomics heading into 2026.


    Produced and hosted by Jonathan D. Grinstein, PhD

    Audio mixed and mastered by David Mosely

    Brought to you by Inside Precision Medicine (SAGE Publishing)

    Hosted on Acast. See acast.com/privacy for more information.
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    42 mins
  • David Fischel: Surgical Robotics for Superhuman and Remote Operations

    David Fischel: Surgical Robotics for Superhuman and Remote Operations
    Dec 3 2025

    Precision medicine isn’t just molecular—it’s anatomical. Even as gene editing advances, many conditions still demand exquisitely targeted surgical care. That’s the world envisioned by Stereotaxis CEO David Fischel, where operations become remote, cockpit-guided missions. Using magnetic “invisible fingers,” surgeons steer ultra-soft catheters with sub-millimeter precision through fragile vessels. After two decades and 170,000 patients, Stereotaxis has reshaped cardiac procedures into robotic navigation—bridging genomics, anatomy, and the future of intervention.


    Produced and hosted by Jonathan D. Grinstein, PhD

    Audio mixed and mastered by David Mosely

    Brought to you by Inside Precision Medicine (SAGE Publishing)


    Hosted on Acast. See acast.com/privacy for more information.
    Show More Show Less
    59 mins
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