The Genesis Mission is a national effort to accelerate discovery by uniting AI, supercomputing, experiments, and the infrastructure of the national laboratories. This episode explores the problem Genesis is trying to solve, the growing gap between the pace of scientific discovery and the scale of the challenges facing the nation. At Lawrence Livermore National Laboratory, this vision is turning into a reality through infrastructure, workforce training, and governance.

Guests featured (in order of appearance):

• Dario Gil - Department of Energy Undersecretary for Science and the Director of the Genesis Mission
• Rob Neely - Associate Director for Weapon Simulation and Computing, LLNL
• Lori Diachin - Principal Deputy for Computing, LLNL

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Big Ideas Lab is a Mission.org original series.

Executive Produced by Levi Hanusch.

Sound Design, Music Edit and Mix by Matthew Powell.

Script by Caroline Kidd

Story Editing by Levi Hanusch.

Audio Engineering and Editing by Matthew Powell.

Narrated by Matthew Powell.

Video Production by Levi Hanusch.

Brought to you in partnership with Lawrence Livermore National Laboratory.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Scientists are simulating cyber attacks and system failures on real-world energy infrastructure - without ever putting the actual grid at risk.

This is Skyfall at Lawrence Livermore National Laboratory.

From real-world incidents like the Ukraine power grid cyberattack 2015 to cascading failures across interconnected systems, this episode explores how cyber-physical incidents can disrupt critical infrastructure in the United States - and how scientists at Skyfall are working to understand and prepare for them. Researchers are using simulation, AI and new approaches like the immune infrastructure framework to understand those risks - and design systems that can adapt and recover when things go wrong.

Guests featured (in order of appearance):

• Nate Gleason - Cyber and Infrastructure Resilience (CIR) Program Lead, LLNL
• Vaibhav Donde - Associate Program Lead, CIR, LLNL
• Colin Ponce - Computer Scientist, CIR, LLNL

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Big Ideas Lab is a Mission.org original series.

Executive Produced by Levi Hanusch.

Sound Design, Music Edit and Mix by Matthew Powell.

Story Editing by Levi Hanusch.

Audio Engineering and Editing by Matthew Powell.

Narrated by Matthew Powell.

Video Production by Levi Hanusch.

Brought to you in partnership with Lawrence Livermore National Laboratory.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In a remote corner of the Nevada desert, scientists at JASPER study one of the most consequential materials on Earth: plutonium. This is the story of how a bold experimental concept became a trusted national asset. By utilizing a two-stage gas gun, researchers create extreme conditions for less than a microsecond, generating the precise data that helps to validate and strengthen U.S. science-based stockpile stewardship. The work demands extraordinary precision, complete containment, and an unwavering focus on national security.

Guests featured (in order of appearance):

• David Bober - JASPER Team Lead, LLNL
• Ricky Chau - JASPER Execution Lead, LLNL

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Big Ideas Lab is a Mission.org original series.

Executive Produced by Levi Hanusch.

Script by Caroline Kidd.

Sound Design, Music Edit and Mix by Matthew Powell.

Story Editing by Levi Hanusch.

Audio Engineering and Editing by Matthew Powell.

Narrated by Matthew Powell.

Video Production by Levi Hanusch.

Brought to you in partnership with Lawrence Livermore National Laboratory.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

From corrosion-resistant coatings to next-generation batteries and stronger wind turbines, some of today’s toughest industrial challenges share a surprising common thread: they’re being solved inside a computer. In this episode, we explore the High Performance Computing for Energy Innovation program. This collaboration between U.S. national laboratories and private industry uses advanced supercomputing to tackle real-world problems in manufacturing, energy, and materials science. With nearly 200 projects across 12 Department of Energy labs, the program is helping companies reduce energy use, cut carbon emissions, and strengthen American manufacturing by tackling complex industrial challenges with computational science.

Guests featured (in order of appearance):

• Brandon Wood, Project Lead, LLNL
• Aaron Fisher, HPC4EI Director, LLNL
• Yeping Hu, Project Lead, LLNL

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Big Ideas Lab is a Mission.org original series.

Executive Produced by Levi Hanusch.

Script by Caroline Kidd.

Sound Design, Music Edit and Mix by Matthew Powell.

Story Editing by Levi Hanusch.

Audio Engineering and Editing by Matthew Powell.

Narrated by Matthew Powell.

Video Production by Levi Hanusch.

Brought to you in partnership with Lawrence Livermore National Laboratory.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Behind every safeguard of national security lies a world few ever see. Inside Lawrence Livermore National Laboratory, scientists and engineers are redefining how explosions are developed, modeled, and tested to ensure the United States maintains a safe, secure, and reliable deterrent. From molecule-level physics to exascale computing systems, the Energetic Materials Center is the hub of subject matter expertise in explosive science at LLNL. EMC is partnering in global scientific collaborations aimed at reducing risk, advancing security, and shaping the future of deterrence in a rapidly changing world.

Guests featured (in order of appearance):

• Lara Leininger, Director of Energetic Materials Center, LLNL
• Alex Gash, Deputy Director of Energetic Materials Center, LLNL

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Big Ideas Lab is a Mission.org original series.

Executive Produced by Levi Hanusch.

Script by Caroline Kidd.

Sound Design, Music Edit and Mix by Matthew Powell.

Story Editing by Levi Hanusch.

Audio Engineering and Editing by Matthew Powell.

Narrated by Matthew Powell.

Video Production by Levi Hanusch.

Brought to you in partnership with Lawrence Livermore National Laboratory.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

At the center of every experiment at Lawrence Livermore National Laboratory’s National Ignition Facility is a target - a tiny, precisely engineered object built to withstand the intensity of the world’s highest energy laser system. Join us as we explore target fabrication: the craft behind capsules made of diamond, their intricate assemblies, and cross continental journeys that make fusion experiments possible.

Guests featured (in order of appearance):

• Michael Stadermann, Target Fabrication Program Manager, LLNL
• Jared Hund, LLNL Contract Manager at General Atomics

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Big Ideas Lab is a Mission.org original series.

Executive Produced by Levi Hanusch.

Script by Dara Bates.

Sound Design, Music Edit and Mix by Matthew Powell.

Story Editing by Levi Hanusch.

Audio Engineering and Editing by Matthew Powell.

Narrated by Matthew Powell.

Video Production by Levi Hanusch.

Brought to you in partnership with Lawrence Livermore National Laboratory.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The world’s most demanding science never sleeps.

From facilities that operate around the clock to the people monitoring safety, power, and infrastructure overnight, this episode goes behind the scenes of the invisible operations at Lawrence Livermore National Laboratory that keep critical science moving forward - even when nothing appears to be happening.

Guests featured (in order of appearance):

• Cynthia Rivera, Principal Associate Director of Operations & Business, LLNL
• Robert Scripp, Emergency Management Department Head, LLNL

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Big Ideas Lab is a Mission.org original series.

Executive Produced by Levi Hanusch.

Script by Elizabeth Sherman.

Sound Design, Music Edit and Mix by Matthew Powell.

Story Editing by Levi Hanusch.

Audio Engineering and Editing by Matthew Powell.

Narrated by Matthew Powell.

Video Production by Levi Hanusch.

Brought to you in partnership with Lawrence Livermore National Laboratory.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

At Lawrence Livermore National Laboratory’s National Ignition Facility, scientists recreate the most extreme conditions in the universe. Through the Discovery Science Program, researchers and students from around the world gain rare access to this machine to run experiments that exist for only a fraction of a second, yet reshape what we know about stars, planets, and matter itself. These experiments don’t just explore the cosmos; they create a shared laboratory for discovery and the training ground for the next generation of scientists who will evaluate the safety, security and effectiveness of our nation’s nuclear deterrence.

Guests featured (in order of appearance):

•  Dan Kalantar, Chief Systems Engineer for Experimental Systems at NIF, LLNL
• Tilo Doeppner, Experimental Physicist at NIF, LLNL

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Big Ideas Lab is a Mission.org original series.

Executive Produced by Levi Hanusch.

Script by Caroline Kidd.

Sound Design, Music Edit and Mix by Matthew Powell.

Story Editing by Levi Hanusch.

Audio Engineering and Editing by Matthew Powell.

Narrated by Matthew Powell.

Video Production by Levi Hanusch.

Brought to you in partnership with Lawrence Livermore National Laboratory.

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.