Carbamazepine
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Carbamazepine
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- Trade: Tegretol
- Class: Anticonvulsant
- MOA: Binds preferably to voltage gated Sodium channels in their inactive conformation, which prevents repetitive and sustained firing of an action potential.
- Indications: Partial and generalized tonic – clonic seizures
- Contraindications: AV Block, bundle branch block, agranulocytosis, bone marrow supression, monoamine oxidase inhibitor therapy
- Side effects: Dizziness, drowsiness, ataxia, N/V, blurred vision, confusion, headache, transient diplopia, visual hallucinations, life threatening rashes.
- Dosing:
Adult:
200mg PO
Pediatric:
6-12 years old: 100mg PO
Less then 6: 10mg/kg PO
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