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Derms and Conditions

Derms and Conditions

Written by: Dermsquared
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 Hear from the leading dermatologists and experts as they discuss the hottest topics in dermatology. Tune in for clinical practice tips and treatment pearls you can implement quickly and efficiently into your busy practices!2025 Dermsquared Hygiene & Healthy Living Physical Illness & Disease
Episodes
  • Greatest Hits of Derms and Conditions 2025

    Greatest Hits of Derms and Conditions 2025
    Dec 18 2025
    In this 2025 Year in Review solo episode of Derms and Conditions, host James Q. Del Rosso, DO, reflects on the standout conversations, clinical insights, and new formats that shaped the series over the past year. Dr Del Rosso opens by highlighting the launch of Tea with Dr. D, a sister vodcast that brings expert discussions to video, incorporating slides and procedural footage. He spotlights an episode with HS expert Lauren Lam, MD, who walks through comprehensive hidradenitis suppurativa management from patient check-in through long-term care. He also reviews Spilling the Tea with Dr. D, a hybrid audio-video mailbag format that addresses listener-submitted clinical questions. He then revisits key moments from the core Derms and Conditions series, beginning with Michael Payette, DO, who discussed building a dedicated HS clinic, collaborating with nondermatology providers, and his early adoption of GLP-1 agents for inflammatory disease management. Additional highlights include an episode with E. James Song, MD, on modern nb-UVB phototherapy units and practical guidance for safe implementation, as well as a unique discussion with Clay Cockerell, MD, JD, on estate planning considerations for physicians. Vitiligo emerged as a recurring focus in 2025, with expert insights from Seemal Desai, MD, and Pearl Grimes, MD, covering disease assessment, treatment timelines, topical ruxolitinib, oral therapies, phototherapy, and running a dedicated vitiligo center. Dr Del Rosso also revisits episodes on extended-release minocycline for rosacea, oral JAK inhibitors in older adults, challenging case-based discussions, evolving approaches to photoprotection and skin care counseling, and emerging therapies across alopecia areata, hyperhidrosis, tyrosine kinase 2 inhibition in psoriasis, and chronic hand eczema, including a recent FDA approval. Tune in to the full episode for a look back at a year of clinically relevant education aimed at supporting dermatologists in everyday practice.
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    29 mins
  • Watch and Listen: How You Can Integrate Regenerative Procedures to Treat Alopecia

    Watch and Listen: How You Can Integrate Regenerative Procedures to Treat Alopecia
    Dec 11 2025
    In this episode of Tea with Dr. D, host James Q. Del Rosso, DO, is joined by Gary Goldenberg, MD, for an in-depth discussion on integrating procedural dermatology, particularly regenerative treatments for hair loss, into a busy private practice. Together, they explore considerations for patient selection and the clinical value these procedures bring to aesthetic and medical dermatology settings. The conversation begins with an overview of platelet-rich plasma (PRP), including its evolution in the US and the growing body of evidence supporting its role in androgenetic alopecia, telogen effluvium, alopecia areata, and scarring alopecia. Dr Goldenberg outlines PRP as a regenerative therapy rather than a hair-specific treatment, describing how growth factors help stimulate dormant follicles and prolong the anagen phase. He reviews the preparation process, ideal candidates, contraindications, and why early intervention yields the best outcomes. Procedural videos throughout the episode illustrate PRP techniques, from multi-needle mesotherapy devices to targeted injections with a 30-gauge needle, and demonstrate approaches to analgesia and treatment tailoring by pattern of loss. The discussion extends to the role of exosomes in regenerative dermatology. Dr Goldenberg explains their mechanism, the distinction between human- and plant-derived products, and his rationale for combining exosomes with PRP when feasible. Additional videos highlight injection and microneedling-based delivery methods, offering insight into how these modalities complement each other in alopecia. Tune in to the full episode for expert guidance
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    58 mins
  • Pearls from “The Pearl”: A Time Capsule of Knowledge & Experience with Vitiligo

    Pearls from “The Pearl”: A Time Capsule of Knowledge & Experience with Vitiligo
    Dec 4 2025
    In this episode of Derms and Conditions, host James Q. Del Rosso, DO, sits down with Pearl Grimes, MD, to discuss the latest understanding and management of vitiligo, a field experiencing significant scientific and therapeutic momentum. With the approval of topical ruxolitinib and multiple oral JAK inhibitors on the horizon, these developments are enabling clinicians to better tailor therapy to the diverse needs of their patients. They begin with a discussion on setting patient expectations around treatment duration. With vitiligo therapies requiring long-term commitment, Dr Grimes explains that it is a chronic disease requiring ongoing management, whether using older therapies or newer JAK inhibitors. By establishing realistic expectations early, patients are less likely to abandon therapy prematurely when repigmentation is not yet visible. They also address common misconceptions around skin type. While vitiligo is more noticeable in darker skin, its prevalence is similar across all skin tones. In her clinical experience and in ruxolitinib trials and emerging oral JAK data, Dr Grimes has observed meaningful repigmentation across phototypes, with no major response differences that would warrant altering expectations for lighter-skinned patients. They next discuss practical therapeutic considerations, including typical timelines for assessing response and the role of regimen adjustments during the first year. When using ruxolitinib, she considers disease extent, anatomic site, and expected repigmentation patterns, noting that the face and neck tend to respond best, with the hands remaining challenging. She also reviews her approach to initial workup, including autoimmune screening, particularly for thyroid disease, as well as her use of supplements to mitigate oxidative stress pathways implicated in melanocyte destruction. Tune in to the full episode to hear Dr Grimes share additional clinical pearls, discuss combination strategies, and offer guidance on setting patients up for long-term success in vitiligo management.
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    33 mins
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