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Does Fasting Cause Muscle Loss? Understanding the Metabolic Switch

Does Fasting Cause Muscle Loss? Understanding the Metabolic Switch

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One of the biggest concerns people have about intermittent fasting is whether it leads to muscle loss.

In this episode, we explore what actually happens inside the body during fasting. We walk through the different fuel sources the body uses — from blood glucose to glycogen and eventually stored fat — and explain what people mean when they talk about the “metabolic switch.”

We also discuss the role of hormones like insulin and growth hormone during fasting, what the current research suggests about muscle preservation, and why being fat-adapted matters.

Finally, we cover practical considerations around fasting duration, exercise, and nutrition so that muscle can be preserved while fasting.


Research: Moro et al. 2016 Journal of Translational Medicine time restricted feeding resistance training


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