Electrolytes Aren’t Numbers: Membranes, Gradients, and Why Cells Fail First
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Electrolytes Aren’t Numbers: Membranes, Gradients, and Why Cells Fail First
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About this listen
In this episode of Paging Dr. Samir, we move from homeostasis down to the cellular level to explain why organ failure always starts with membrane failure. Dr. Samir characterizes cell membranes as control interfaces, not anatomical diagrams, and explains how transporters, pumps, and gradients drive excitability, fluid shifts, and electrical stability.
Using real clinical examples like hyperkalemia, arrhythmias, edema, and altered mental status, this episode connects electrolyte abnormalities to membrane potential and explains why treatment priorities focus on stabilizing membranes before chasing lab values. Passive transport, active transport, the sodium-potassium pump, calcium handling, and membrane potentials are all integrated into a practical, bedside-ready framework.
If physiology has ever felt fragmented or memorization-heavy, this episode shows how transport and gradients unify everything from EKG changes to emergency management. This is physiology intended for use, not memorization.
Medical physiology explained through cell membranes, electrolytes, and transport. Learn how sodium, potassium, calcium, and membrane potentials drive EKG changes, arrhythmias, edema, and clinical decision-making in real patient cases.