Dr. Will Bulsiewicz is a board-certified gastroenterologist, three-time New York Times bestselling author, and one of the world’s leading voices on the gut microbiome. His new book, Plant Powered Plus, is about inflammation and how to reduce it by healing the gut.
In this episode, we go beyond “eat more fibre” and break down the real driver behind modern disease: chronic inflammation.
We explore why over 130 conditions — from heart disease to depression — share the same inflammatory root, how your gut controls 70% of your immune system, and why stress, trauma, loneliness, and modern living may be damaging your gut more than food alone.
Dr. B explains the gut–immune connection in simple terms, reveals what’s changed in the last 125 years, and shares the daily habits that genuinely lower inflammation — including fibre, polyphenols, fermented foods, omega-3s, and even forgiveness.
If you care about energy, resilience, mental clarity, and long-term health — this episode is essential listening.
Timestamps:
00:00 – Dr Will Bulsiewicz’s journey from gut health to inflammation
00:50 – The inflammation crisis & 130+ diseases
04:15 – Is inflammation a cause or consequence?
08:44 – The gut–immune triangle explained
12:05 – Why your gut is your first line of defence
16:55 – Acute vs chronic inflammation
18:30 – Why medicine focuses on organs
21:39 – How modern medicine became symptom-focused
24:46 – Why 70% of the immune system lives in the gut
27:00 – Your microbiome tells the story of your life
28:46 – What’s really driving inflammation today
33:55 – Science vs “holistic health”
37:48 – The mind–body connection (mechanisms)
39:55 – How trauma affects the brain & body
42:10 – Stress, CRH & the gut barrier
45:37 – Chronic stress & inflammation
46:45 – Why stress disrupts digestion
48:28 – The patient who healed by quitting her job
49:04 – Sympathetic vs parasympathetic states
50:04 – What changed in the last 125 years
52:30 – Loneliness, safety & health
54:39 – Loneliness vs smoking (health impact)
55:43 – What you can practically do
56:10 – Fibre & short-chain fatty acids
58:17 – Polyphenols & colourful foods
1:00:51 – Healthy fats & omega-3s
1:02:00 – Fermented foods & inflammation
1:03:51 – The 15-minute morning routine
1:05:00 – Forgiveness, stress & healing
1:07:04 – Closing thoughtsConnect with us:
https://freedompact.co.uk/newsletter (Healthy, Wealthy & Wise Newsletter)
www.Instagram.com/freedompact
www.twitter.com/freedompactpod
Email: freedompact@gmail.com
https://Tiktok.com/personaldevelopment
LISTEN ON SPOTIFY:https://open.spotify.com/show/1R0aL3nQYXcYFc0FaNai08?si=2ea63f84e2da49f2
Follow Dr. B for practical, science-backed strategies on gut health and inflammation:
https://theguthealthmd.com
https://www.instagram.com/theguthealthmd
Youtube: @theguthealthmd
BUY Plant Powered Plus - https://theguthealthmd.com/plantpoweredplus
Feb 22 202656 mins