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Game Over: c*ncer

Game Over: c*ncer

Written by: Hi Hello Labs Network
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Through poignant interviews with pediatric cancer survivors, families, medical professionals, and advocates, Game Over: c*ncer sheds light on the realities of childhood cancer. Each episode explores the efforts and advocacy taking place to find more solutions and make changes for this fatal disease. Hope exhibited by these young warriors and their loved ones is also crucial to our message. From discussing the latest research advancements to sharing personal stories of triumph and loss, the show aims to spark meaningful conversations, foster community support, and drive action toward a world free of childhood cancer. Join us in amplifying these voices, raising awareness, and standing in solidarity with these tiny champs and their families.Copyright Hi Hello Labs Network Economics Management Management & Leadership
Episodes
  • 54. Immunotherapy Breakthroughs with Dr. Gregory Friedman

    54. Immunotherapy Breakthroughs with Dr. Gregory Friedman
    Jul 7 2026
    What does the future of pediatric cancer treatment actually look like?

    In this episode of Game Over: c*ncer, hosts Dana Nichols and Val Solomon sit down with Dr. Gregory Friedman pediatric oncologist, CKc-funded researcher, and chair of the Scientific Advisory Board at Cannonball Kids’ cancer Foundation (CKc), to talk about one of the most exciting areas in childhood cancer research: oncolytic viral therapy.

    Dr. Friedman explains how modified cold sore viruses can be used to safely target and kill pediatric brain tumor cells while also triggering the child’s immune system to attack the tumor. He shares the science behind this innovative immunotherapy approach, what his clinical trials have shown so far, and why the future of pediatric brain tumor treatment may depend on combination therapies that work with the immune system rather than against it.

    If you’re interested in pediatric cancer research, immunotherapy, brain tumor treatment, clinical trials, childhood cancer advocacy, or how nonprofit funding helps move science forward, this episode is packed with insight.

    In this episode, we cover:
    • What oncolytic viral therapy is and how it works in pediatric brain tumors
    • Why traditional immunotherapy has struggled in childhood brain cancers
    • How modified viruses may help the immune system recognize and attack cancer
    • Early clinical trial outcomes in children with high-grade glioma
    • Why pediatric cancers need pediatric-specific treatments
    • How research moves from the lab to clinical trials
    • The role of the Scientific Advisory Board at CKc
    • Why funding pediatric cancer clinical trials is so important
    • What the future of immunotherapy for childhood cancer may look like over the next decade
    Dr. Friedman also shares why he believes we may be approaching a new era in pediatric cancer treatment, one driven by smarter, more targeted, and more durable immune-based therapies.If you believe every child deserves better treatment options and a better chance at survival, this conversation matters.

    Learn more about Cannonball Kids' cancer Foundation and support pediatric cancer research: cannonballkidscancer.org

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    Connect with Dana: https://www.linkedin.com/in/danaknichols/
    Connect with Val: https://www.linkedin.com/in/valerie-solomon/

    Upcoming Ckc Events: https://cannonballkidscancer.org/category/make-an-impact/events/

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    Podcast Produced by Hi Hello Labs: Website: https://www.hihellolabs.com/
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    36 mins
  • 53. Quiet Tenacity: A Family's Journey Through Pediatric Cancer

    53. Quiet Tenacity: A Family's Journey Through Pediatric Cancer
    Jun 23 2026
    Quiet Tenacity: A Family's Journey Through Pediatric Cancer

    What happens 10 years after a child hears the words, "You have cancer"?

    In this powerful episode of Game Over: c*ncer, hosts Dana Nichols and Val Solomon welcome Nick and Rachel Mangan, parents of pediatric brain cancer survivor Lantz Mangan, to share their family's incredible journey through diagnosis, treatment, survivorship, and hope.

    At just six years old, Lantz was diagnosed with a rare pediatric brain tumor. Facing impossible decisions about chemotherapy, radiation, clinical treatment options, and long-term side effects, his parents became fierce advocates for innovative cancer care and pediatric cancer research.

    Now, 10 years cancer-free, Lantz is thriving as a teenager, proving why research matters and why organizations like Cannonball Kids' cancer Foundation continue fighting for better treatments for children diagnosed with cancer.

    In this episode, you'll learn:
    -How Lantz's rare brain tumor was diagnosed
    -Why his parents declined radiation treatment
    -The experimental targeted therapy that changed everything
    -The emotional reality of pediatric cancer survivorship
    -How research creates new treatment options for children
    -The importance of second opinions and parent advocacy
    -How Gabriel Therapy Group and Keep On Walking are giving back to families today
    -Why hope and gratitude remain at the center of their journey

    If you're a pediatric cancer family, survivor, advocate, researcher, healthcare professional, or simply someone who believes every child deserves a future, this episode is for you.

    Learn more about Cannonball Kids' cancer Foundation and support pediatric cancer research: cannonballkidscancer.org

    Learn more about Gabrial Therapy Group or Keep on Walking: www.gabrieltherapygroup.com
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    Connect with Dana: https://www.linkedin.com/in/danaknichols/
    Connect with Val: https://www.linkedin.com/in/valerie-solomon/

    Upcoming Ckc Events: https://cannonballkidscancer.org/category/make-an-impact/events/

    ----------------------------------
    Podcast Produced by Hi Hello Labs: Website: https://www.hihellolabs.com/
    Show More Show Less
    50 mins
  • 52. How do laws, funding, and advocacy shape the future of childhood cancer research?

    52. How do laws, funding, and advocacy shape the future of childhood cancer research?
    Jun 9 2026
    In this episode of Game Over: c*ncer, hosts Dana Nichols and Val Solomon welcome Dr. Susan Weiner, founder of Children's Cancer Cause, pediatric cancer advocate, and national leader in childhood cancer policy.

    For more than 25 years, Dr. Weiner has worked alongside families, researchers, legislators, and advocacy organizations to improve childhood cancer treatment, survivorship care, pediatric drug development, and federal cancer research funding.

    This conversation explores the legislative victories that have transformed pediatric oncology, including the STAR Act, the RACE for Children Act, and efforts to improve survivorship resources for childhood cancer survivors. Dr. Weiner also shares how parents, survivors, and advocates can influence public policy and help secure funding for life-saving childhood cancer research.

    If you're interested in pediatric cancer research, childhood cancer advocacy, cancer survivorship, healthcare policy, rare disease research, clinical trials, federal research funding, or how families can create change, this episode is essential viewing.

    For more information on Children's Cancer Cause, visit https://www.childrenscancercause.org. There you will find many resources to help you get started including an advocacy toolkit.

    To view proposed pediatric cancer legislation, visit the Pediatric Cancer Action Network at https://www.pcanaction.org.

    At Cannonball Kids' cancer Foundation, we believe every child deserves access to better treatment options and a brighter future.

    Through research funding, education, and advocacy, we're working to accelerate progress in pediatric cancer.
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    Connect with Dana: https://www.linkedin.com/in/danaknichols/
    Connect with Val: https://www.linkedin.com/in/valerie-solomon/

    Upcoming Ckc Events: https://cannonballkidscancer.org/category/make-an-impact/events/

    ----------------------------------
    Podcast Produced by Hi Hello Labs: Website: https://www.hihellolabs.com/
    Show More Show Less
    39 mins
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