Matt Parlmer is the founder and CEO of General Fabrication Company, a self-reproducing factory company.

We cover the origins of Gen Fab in the realization that we now have the tools to build machines that build themselves (see: The Von Neumann Constructor), the possibilities created by small modular manufacturing in electronics, robotic wet labs, and more; building a vertically integrated industrial company, light industrial parts farms, the need for American industrial policy to include civilian industry in re-industrialization strategy, levers for re-shoring American manufacturing, the unexpected passing of our good friend, Nick Simmons, and the future of General Fabrication.

Links:

• Support Nick Simmons' wife and family's GoFundMe: https://www.gofundme.com/f/honoring-nick-simmons-life-and-legacy
• Matt Parlmer's memorial post for Nick Simmons: https://mattparlmer.substack.com/p/remembering-nick-simmons
• General Fabrication website: https://www.genfab.co/
• Matt Parlmer on X: https://x.com/mattparlmer
• General Fabrication on X: https://x.com/genfabco

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Aneil Mallavarapu is a biochemist, award winning computer scientist, and Managing Partner at Humain Ventures; investing in early stage life science and health tech startups.

We talk about his pioneering work in systems biology at Harvard that led to the creation of Little b, a programming language for modeling biological systems with modularity and abstraction, the phenomenology of consciousness, the “hard problem” of consciousness, taking consciousness as fundamental, the limits of radical materialism, why our brains are not like classical computers, reconciling theories of consciousness with physics, the computational intractability of consciousness, the specter of AI civil rights, and Austin as the epicenter of the emerging science of the mind.

Aneil on X: https://x.com/aneilbaboo

His paper, "Programming with models: Modularity and abstraction provide powerful capabilities for systems biology"

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If you enjoyed this talk, please leave a review on Spotify/iTunes.

Listen on:

Youtube: https://www.youtube.com/@alexmurshak

Apple: https://podcasts.apple.com/us/podcast/hacking-state/id1689677076

Spotify: https://open.spotify.com/show/1XB9XYULrAY4dp0qIJVvCg

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Kyle Housley is a writer and co-host of a new podcast, Horizons Review, with longtime friend of the show, Cody Moser, exploring neglected intellectual texts and thinkers. We discuss the pathologization of normal relationship dynamics through misused psychological terminology, and extensively examine Second Amendment jurisprudence, particularly Kyle's disagreement with the Heller case on original meaning grounds.

Kyle critiques how terms like "narcissism" and "transactional relationships" are misapplied to pathologize healthy interpersonal expectations and natural give-and-take in friendships and romantic partnerships. He argues this reflects broader cultural problems with dismissing relational obligations in favor of personal convenience.

The majority of our conversation focuses on Kyle's disagreement with the 2008 Heller case. He argues that the core holding identifying self-defense as the primary protected right is wrong on original meaning grounds. Instead, he contends the amendment's original purpose was to protect citizens' right to bear arms most useful in military service to maintain effective militias, not individual self-defense which was already protected under common law.

Kyle provides extensive historical context on the founders' deep concerns about standing armies versus citizen soldiers, heavily influenced by Roman Republic history and fears that professional armies would lead to the same factional civil wars that destroyed Rome. We explore the distinction between a "right to rebellion" versus organized resistance, the founders' view of standing armies as mercenaries, and how the militia clause connects to republican virtue and citizenship.

We conclude by examining modern challenges to Second Amendment interpretation, including 3D-printed guns and drone warfare, and how technological advances create new questions about effective citizen militia capability in the 21st century.

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If you enjoyed this talk, please leave a review on Spotify/iTunes.

Listen on:

Youtube: https://www.youtube.com/@alexmurshak

Apple: https://podcasts.apple.com/us/podcast/hacking-state/id1689677076

Spotify: https://open.spotify.com/show/1XB9XYULrAY4dp0qIJVvCg

RSS: https://feed.podbean.com/hackingstate/feed.xml