BBDC: Assessing Temporomandibular Joints in Patients with Osteogenesis Imperfecta
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BBDC: Assessing Temporomandibular Joints in Patients with Osteogenesis Imperfecta
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Transcript:
New research from the Brittle Bone Disorders Consortium (BBDC), a research group of the Rare Diseases Clinical Research Network.
Assessing Temporomandibular Joints in Patients with Osteogenesis Imperfecta.
This summary is based on a paper published in the journal Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology on September 16, 2025.
Osteogenesis imperfecta (OI) is a group of inherited connective tissue disorders associated with a wide range of symptoms, including fragile bones that break easily. Individuals with OI can experience problems with bone formation and function.
In this study, researchers assessed temporomandibular joints—which connect the jawbone to the skull—in patients with OI. First, the team used cone-beam computed tomography (CBCT) to create 3D images of the temporomandibular joints of 48 OI patients and 48 age- and sex-matched controls. Next, they evaluated mandibular condylar volume and height.
Results showed that individuals with OI had significantly reduced condylar volume and height. Authors note that these findings indicate impaired and delayed condylar development consistent with overall skeletal maturation delay in OI.
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