Nicolas Grundmann is the Co-founder and CEO of Ember Health, which provides IV ketamine treatments for depression. As a board-certified emergency medicine physician, he launched Ember Health to create more effective, patient-centered treatment options. Nicolas is also a faculty member at the American Society of Ketamine Physicians, Psychotherapists and Practitioners, and is the Co-founder of Chenla Children's Healthcare, which improves pediatric care in Cambodia.

Mental health treatment is evolving as clinicians search for options that outperform traditional approaches. From data-driven care to treating trauma, anxiety, and depression together, how can clinicians create evidence-based ketamine treatments?

According to emergency medicine physician Nicolas Grundmann, effective ketamine treatment starts with rigorous evidence, longitudinal data, and close care coordination. He emphasizes symptom-driven dosing, regular measurement using validated tools, and proactive follow-up to catch relapses early. Clinicians should also integrate outside therapists, help patients relearn emotional regulation after depression lifts, and avoid one-size-fits-all models.

In this episode of Living Medicine, Dr. Sandy Newes talks with Nicolas Grundmann, Co-founder and CEO of Ember Health, about evidence-based ketamine treatment for depression. Nicolas talks about using real-world data to guide care, treating depression with comorbid PTSD and anxiety, and whether to include therapy during ketamine sessions.

Dr. Sandra (Sandy) Newes, PhD, is a licensed psychiatrist and the Co-founder and Programming Director of Living Medicine Institute, which offers psychedelic-assisted psychotherapy training programs. With over 25 years of clinical experience as a psychedelic-assisted psychotherapist, she specializes in anxiety, chronic stress, trauma, and recovery. Dr. Newes is also an educator and speaker offering workshops, events, and education on psychedelic-assisted psychotherapy and the intersection of nature connection, trauma, and mental health.

Many people exploring mental health treatments seek options that go deeper than traditional talk therapy. They want approaches that help them access, process, and move through the patterns that keep them stuck. How can you determine which tools support meaningful change?

According to psychologist and ketamine-assisted psychotherapy specialist Dr. Sandy Newes, the solution lies in combining medicine with skilled therapeutic guidance. Preparation, integration, and a strong relational container turn chemical experiences into transformation. Dr. Newes recommends working in a structured series of sessions, tracking the narrative and the body, and ensuring clients feel safe enough to explore difficult material. This process can open space for clarity, emotional release, and genuine healing.

In this episode of Living Medicine, Chad Franzen of Rise25 hosts Dr. Sandy Newes, Co-founder and Programming Director of Living Medicine Institute, to discuss ketamine-assisted psychotherapy for trauma care. Dr. Newes talks about its unique clinical utility, common misconceptions about dosing, and how trauma-informed care shapes the therapeutic experience.

Dr. Raymond Turpin is the Clinical and Executive Director of The Pearl Institute, a nonprofit organization dedicated to advancing trauma-informed care and psychedelic-assisted therapies. He has worked in psychiatric hospitals, psychiatric emergency units, residential treatment facilities, juvenile detention, schools, and community mental health clinics. Before The Pearl Institute, Dr. Turpin co-founded Jackson County Psychological Services, which provided free and reduced-cost mental health services to the students and families of the Jackson County Public School system.

Psychedelic-assisted therapy is reshaping how clinicians understand trauma, resilience, and healing. With veterans, first responders, and countless others still struggling despite traditional treatments, many are wondering whether a different therapeutic pathway is finally within reach. What happens when medicine, neuroscience, and expanded states of consciousness converge? How can clinicians bring innovative treatments to people who need them most?

With decades of experience in trauma-focused psychology, Dr. Raymond Turpin believes that meaningful healing begins by accessing the deeper layers of the psyche that conventional talk therapy often can't reach. He emphasizes the importance of preparation, safety, and intentional integration, noting that even profound non-ordinary experiences require commitment and follow-through to create transformation. Relational support, skilled guidance, and a willingness to engage with inner material can catalyze healing.

In this episode of Living Medicine, Dr. Sandy Newes talks with Dr. Raymond Turpin, Clinical and Executive Director of The Pearl Institute, about psychedelic-assisted trauma therapy. Dr. Turpin shares his path into MDMA research, how his team became an expanded access site treating four clients, and why his view of ketamine evolved through clinical experience.