the revolutionary drug Acoramidis, a breakthrough FDA-approved treatment for Transthyretin Amyloid Cardiomyopathy (ATTR-CM), exploring its inspiring development journey from Stanford’s labs to clinical success. Learn how scientists like Dr. Isabella Graef and Dr. Mamun Alhamadsheh designed this TTR stabilizer to combat a rare, life-threatening heart disease, its impressive clinical trial results showing improved survival and reduced hospitalizations, and key pharmacological details from dosing to drug interactions. Discover the collaborative efforts behind this medical milestone and why Acoramidis represents hope for patients and a triumph of translational science. Tune in for a compelling blend of innovation, perseverance, and lifesaving medicine!

The Link to the Drive that contains picture of the T-4 Binding Site : https://drive.google.com/drive/folders/1_L-TB8-LrtEXKdvO8ZWyszspqpup2-kx?usp=sharing

Tape here to discover me on social media: https://taplink.cc/abdelghaniabdelli

Some of our Bibliographic Ressources in cas you wanna deep your searches on Acoramidis:

https://med.stanford.edu/news/all-news/2024/11/spark-acoramidis.html

https://www.nejm.org/doi/full/10.1056/NEJMoa2305434

https://www.drugs.com/monograph/acoramidis.html

https://go.drugbank.com/drugs/DB17999

https://pubmed.ncbi.nlm.nih.gov/38197816/

In this episode of Alsan's Pharmaceutical Journey, host Abdelghani Abdelli dives into the fascinating story of Nobiletin, a little-known molecule found in mandarin oranges from Kochi, Japan—a town famous for its residents living past 100 in good health. Discover how Nobiletin shows promise in regulating circadian rhythms, fighting metabolic disorders, and even protecting against Alzheimer’s disease. Backed by scientific research and simplified explanations, this episode explores why Nobiletin could be a future game-changer in therapeutic medicine.

link of the drive that contains the graphical abstract of the experience applied on diet induced mouse :

https://drive.google.com/drive/folders/1jJ8o-Fdgrv74Ax7E5dCF3MKjSkBSJfhX?usp=sharing

Pharmacist Daily Store link: https:https://alsanmarketing21.systeme.io/alsafashion⁠