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Scrubcast

Scrubcast

Written by: Stanford Surgery
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 The Department of Surgery at Stanford UniversityAll rights reserved Science
Episodes
  • Exploring the Intersection of Surgery and Cancer Research with Dr. Dan Delitto

    Exploring the Intersection of Surgery and Cancer Research with Dr. Dan Delitto
    Feb 2 2026
    Dr. Dan Delitto is an assistant professor of surgery at Stanford University specializes in surgical oncology and holds a PhD in immunology. On this episode, Dr. Delitto reflects on his decision to pursue an MD-PhD pathway during residency and discusses the recent advancements in single-cell RNA sequencing technology that his lab has acquired. He explains the complex role of fibroblasts in cancer development, particularly in pancreatic ductal carcinoma, highlighting how these cells can both promote and hinder tumor growth. The conversation includes a lightning round, during which Dr. Delitto shares his admiration for his mentor, Steve Hughes, and offers succinct advice on the importance of surgical experience. He also mentions his preference for trance music while working and shares his excitement about ongoing and future research projects in his lab, which include investigations into various cancers, such as sarcomas. Link to Nature Cancer article “Cancer-derived mitochondria fuel fibroblasts to become pro-tumorigenic.”: https://www.nature.com/articles/s43018-025-01005-1 Link to Cell Reports article “Disruption of fibroblast MYD88 signaling promotes antitumor immunity in pancreatic ductal adenocarcinoma”: https://www.cell.com/cell-reports/fulltext/S2211-1247(25)01118-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124725011180%3Fshowall%3Dtrue
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    14 mins
  • 20 years of Improving Transplant Tolerance with Dr. Stephan Busque

    20 years of Improving Transplant Tolerance with Dr. Stephan Busque
    Dec 1 2025
    This episode features Stanford Professor and transplant surgeon Dr. Stephan Busque. He discusses his extensive experience in the field of tolerance in transplantation, particularly focusing on advancements over the past 20 years. Dr. Busque highlights the significance of his team's work on translating research into clinical practice and mentions that they have the largest experience globally in this field. Additionally, Dr. Busque shares exciting news about Stanford's first allogenic islet cell transplantation for a patient with type one diabetes, indicating a collaborative effort that brought together a multidisciplinary team to achieve this milestone. He reflects on the journey of making islet cell transplants more accessible and expresses hope for new beginnings in this area. The episode wraps up with a lightning round where Dr. Busque discusses the qualities he admires in skilled surgeons, emphasizing the importance of being a well-rounded doctor who not only excels in technical skills but also demonstrates a deep understanding of patient care and connection. Going forward he’s excited for the development of protocols for various transplant scenarios, including open liver transplant tolerance, and indicates that patients with less-than-perfect matches are the next target group for improvements in transplantation techniques
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    30 mins
  • Crohn's Disease and Creeping Fat with Dr. Jeong Hyun

    Crohn's Disease and Creeping Fat with Dr. Jeong Hyun
    Nov 3 2025
    On this episode of Scrubcast, episode of Scrubcast features Dr. Jeong Hyun, an assistant professor in the division of pediatric surgery at Stanford University, discusses his journey to becoming a surgeon scientist. Hyun’s research is focused on Crohn's disease and how strictures develop in the intestines. Shout out to MD/PhD candidate Khristian Bauer-Rowe, who he collaborated with on the September article in Cell looking at the role of creeping fat and CTHRC1+ fibroblasts. The episode also touches on Dr. Hyun's personal interests, including his unexpected love for country music, which he developed while working in Kansas City. The discussion concludes with Dr. Hyun acknowledging the uncertainties in research funding and the importance of vulnerability and resilience in both personal and professional life. Link to article: https://www.cell.com/cell/abstract/S0092-8674(25)01018-9
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    28 mins
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