Episodes

  • #536: Fly inside FastAPI Cloud

    #536: Fly inside FastAPI Cloud
    Feb 10 2026
    You've built your FastAPI app, it's running great locally, and now you want to share it with the world. But then reality hits -- containers, load balancers, HTTPS certificates, cloud consoles with 200 options. What if deploying was just one command? That's exactly what Sebastian Ramirez and the FastAPI Cloud team are building. On this episode, I sit down with Sebastian, Patrick Arminio, Savannah Ostrowski, and Jonathan Ehwald to go inside FastAPI Cloud, explore what it means to build a "Pythonic" cloud, and dig into how this commercial venture is actually making FastAPI the open-source project stronger than ever. Episode sponsors Command Book Python in Production Talk Python Courses Links from the show Guests Sebastián Ramírez: github.com Savannah Ostrowski: github.com Patrick Arminio: github.com Jonathan Ehwald: github.com FastAPI labs: fastapilabs.com quickstart: fastapicloud.com an episode on diskcache: talkpython.fm Fastar: github.com FastAPI: The Documentary: www.youtube.com Tailwind CSS Situation: adams-morning-walk.transistor.fm FastAPI Job Meme: fastapi.meme Migrate an Existing Project: fastapicloud.com Join the waitlist: fastapicloud.com Talk Python CLI Talk Python CLI Announcement: talkpython.fm Talk Python CLI GitHub: github.com Command Book Download Command Book: commandbookapp.com Announcement post: mkennedy.codes Watch this episode on YouTube: youtube.com Episode #536 deep-dive: talkpython.fm/536 Episode transcripts: talkpython.fm Theme Song: Developer Rap 🥁 Served in a Flask 🎸: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @talkpython@fosstodon.org X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @mkennedy@fosstodon.org Michael on X.com: @mkennedy
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    1 hr and 7 mins
  • #535: PyView: Real-time Python Web Apps

    #535: PyView: Real-time Python Web Apps
    Jan 23 2026
    Building on the web is like working with the perfect clay. It’s malleable and can become almost anything. But too often, frameworks try to hide the web’s best parts away from us. Today, we’re looking at PyView, a project that brings the real-time power of Phoenix LiveView directly into the Python world. I'm joined by Larry Ogrodnek to dive into PyView. Episode sponsors Talk Python Courses Python in Production Links from the show Guest Larry Ogrodnek: hachyderm.io pyview.rocks: pyview.rocks Phoenix LiveView: github.com this section: pyview.rocks Core Concepts: pyview.rocks Socket and Context: pyview.rocks Event Handling: pyview.rocks LiveComponents: pyview.rocks Routing: pyview.rocks Templating: pyview.rocks HTML Templates: pyview.rocks T-String Templates: pyview.rocks File Uploads: pyview.rocks Streams: pyview.rocks Sessions & Authentication: pyview.rocks Single-File Apps: pyview.rocks starlette: starlette.dev wsproto: github.com apscheduler: github.com t-dom project: github.com Watch this episode on YouTube: youtube.com Episode #535 deep-dive: talkpython.fm/535 Episode transcripts: talkpython.fm Theme Song: Developer Rap 🥁 Served in a Flask 🎸: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @talkpython@fosstodon.org X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @mkennedy@fosstodon.org Michael on X.com: @mkennedy
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    1 hr and 8 mins
  • #534: diskcache: Your secret Python perf weapon

    #534: diskcache: Your secret Python perf weapon
    Jan 13 2026
    Your cloud SSD is sitting there, bored, and it would like a job. Today we’re putting it to work with DiskCache, a simple, practical cache built on SQLite that can speed things up without spinning up Redis or extra services. Once you start to see what it can do, a universe of possibilities opens up. We're joined by Vincent Warmerdam to dive into DiskCache.

    Episode sponsors

    Talk Python Courses
    Python in Production

    Links from the show diskcache docs: grantjenks.com
    LLM Building Blocks for Python course: training.talkpython.fm
    JSONDisk: grantjenks.com
    Git Code Archaeology Charts: koaning.github.io
    Talk Python Cache Admin UI: blobs.talkpython.fm
    Litestream SQLite streaming: litestream.io
    Plash hosting: pla.sh

    Watch this episode on YouTube: youtube.com
    Episode #534 deep-dive: talkpython.fm/534
    Episode transcripts: talkpython.fm

    Theme Song: Developer Rap
    🥁 Served in a Flask 🎸: talkpython.fm/flasksong

    ---== Don't be a stranger ==---
    YouTube: youtube.com/@talkpython

    Bluesky: @talkpython.fm
    Mastodon: @talkpython@fosstodon.org
    X.com: @talkpython

    Michael on Bluesky: @mkennedy.codes
    Michael on Mastodon: @mkennedy@fosstodon.org
    Michael on X.com: @mkennedy
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    1 hr and 14 mins
  • #533: Web Frameworks in Prod by Their Creators

    #533: Web Frameworks in Prod by Their Creators
    Jan 5 2026
    Today on Talk Python, the creators behind FastAPI, Flask, Django, Quart, and Litestar get practical about running apps based on their framework in production. Deployment patterns, async gotchas, servers, scaling, and the stuff you only learn at 2 a.m. when the pager goes off. For Django, we have Carlton Gibson and Jeff Triplet. For Flask, we have David Lord and Phil Jones, and on team Litestar we have Janek Nouvertné and Cody Fincher, and finally Sebastián Ramírez from FastAPI is here. Let’s jump in. Episode sponsors Talk Python Courses Python in Production Links from the show Guests David Lord Janek Nouvertné Cody Fincher Philip Jones Jeff Triplett Carlton Gibson Carlton Gibson - Django: github.com Sebastian Ramirez - FastAPI: github.com David Lord - Flask: davidism.com Phil Jones - Flask and Quartz(async): pgjones.dev Yanik Nouvertne - LiteStar: github.com Cody Fincher - LiteStar: github.com Jeff Triplett - Django: jefftriplett.com Django: www.djangoproject.com Flask: flask.palletsprojects.com Quart: quart.palletsprojects.com Litestar: litestar.dev FastAPI: fastapi.tiangolo.com Coolify: coolify.io ASGI: asgi.readthedocs.io WSGI (PEP 3333): peps.python.org Granian: github.com Hypercorn: github.com uvicorn: uvicorn.dev Gunicorn: gunicorn.org Hypercorn: hypercorn.readthedocs.io Daphne: github.com Nginx: nginx.org Docker: www.docker.com Kubernetes: kubernetes.io PostgreSQL: www.postgresql.org SQLite: www.sqlite.org Celery: docs.celeryq.dev SQLAlchemy: www.sqlalchemy.org Django REST framework: www.django-rest-framework.org Jinja: jinja.palletsprojects.com Click: click.palletsprojects.com HTMX: htmx.org Server-Sent Events (SSE): developer.mozilla.org WebSockets (RFC 6455): www.rfc-editor.org HTTP/2 (RFC 9113): www.rfc-editor.org HTTP/3 (RFC 9114): www.rfc-editor.org uv: docs.astral.sh Amazon Web Services (AWS): aws.amazon.com Microsoft Azure: azure.microsoft.com Google Cloud Run: cloud.google.com Amazon ECS: aws.amazon.com AlloyDB for PostgreSQL: cloud.google.com Fly.io: fly.io Render: render.com Cloudflare: www.cloudflare.com Fastly: www.fastly.com Watch this episode on YouTube: youtube.com Episode #533 deep-dive: talkpython.fm/533 Episode transcripts: talkpython.fm Theme Song: Developer Rap 🥁 Served in a Flask 🎸: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @talkpython@fosstodon.org X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @mkennedy@fosstodon.org Michael on X.com: @mkennedy
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    1 hr and 2 mins
  • #532: 2025 Python Year in Review

    #532: 2025 Python Year in Review
    Dec 29 2025
    Python in 2025 is in a delightfully refreshing place: the GIL's days are numbered, packaging is getting sharper tools, and the type checkers are multiplying like gremlins snacking after midnight. On this episode, we have an amazing panel to give us a range of perspectives on what matter in 2025 in Python. We have Barry Warsaw, Brett Cannon, Gregory Kapfhammer, Jodie Burchell, Reuven Lerner, and Thomas Wouters on to give us their thoughts. Episode sponsors Seer: AI Debugging, Code talkpython26 Talk Python Courses Links from the show Python Software Foundation (PSF): www.python.org PEP 810: Explicit lazy imports: peps.python.org PEP 779: Free-threaded Python is officially supported: peps.python.org PEP 723: Inline script metadata: peps.python.org PyCharm: www.jetbrains.com JetBrains: www.jetbrains.com Visual Studio Code: code.visualstudio.com pandas: pandas.pydata.org PydanticAI: ai.pydantic.dev OpenAI API docs: platform.openai.com uv: docs.astral.sh Hatch: github.com PDM: pdm-project.org Poetry: python-poetry.org Project Jupyter: jupyter.org JupyterLite: jupyterlite.readthedocs.io PEP 690: Lazy Imports: peps.python.org PyTorch: pytorch.org Python concurrent.futures: docs.python.org Python Package Index (PyPI): pypi.org EuroPython: tickets.europython.eu TensorFlow: www.tensorflow.org Keras: keras.io PyCon US: us.pycon.org NumFOCUS: numfocus.org Python discussion forum (discuss.python.org): discuss.python.org Language Server Protocol: microsoft.github.io mypy: mypy-lang.org Pyright: github.com Pylance: marketplace.visualstudio.com Pyrefly: github.com ty: github.com Zuban: docs.zubanls.com Jedi: jedi.readthedocs.io GitHub: github.com PyOhio: www.pyohio.org Watch this episode on YouTube: youtube.com Episode #532 deep-dive: talkpython.fm/532 Episode transcripts: talkpython.fm Theme Song: Developer Rap 🥁 Served in a Flask 🎸: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @talkpython@fosstodon.org X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @mkennedy@fosstodon.org Michael on X.com: @mkennedy
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    1 hr and 19 mins
  • #531: Talk Python in Production

    #531: Talk Python in Production
    Dec 18 2025
    Have you ever thought about getting your small product into production, but are worried about the cost of the big cloud providers? Or maybe you think your current cloud service is over-architected and costing you too much? Well, in this episode, we interview Michael Kennedy, author of "Talk Python in Production," a new book that guides you through deploying web apps at scale with right-sized engineering. Episode sponsors Seer: AI Debugging, Code talkpython26 Agntcy Talk Python Courses Links from the show Christopher Trudeau - guest host: www.linkedin.com Michael's personal site: mkennedy.codes Talk Python in Production Book: talkpython.fm glances: github.com btop: github.com Uptimekuma: uptimekuma.org Coolify: coolify.io Talk Python Blog: talkpython.fm Hetzner (€20 credit with link): hetzner.cloud OpalStack: www.opalstack.com Bunny.net CDN: bunny.net Galleries from the book: github.com Pandoc: pandoc.org Docker: www.docker.com Watch this episode on YouTube: youtube.com Episode #531 deep-dive: talkpython.fm/531 Episode transcripts: talkpython.fm Theme Song: Developer Rap 🥁 Served in a Flask 🎸: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @talkpython@fosstodon.org X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @mkennedy@fosstodon.org Michael on X.com: @mkennedy
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    1 hr and 21 mins
  • #530: anywidget: Jupyter Widgets made easy

    #530: anywidget: Jupyter Widgets made easy
    Dec 13 2025
    For years, building interactive widgets in Python notebooks meant wrestling with toolchains, platform quirks, and a mountain of JavaScript machinery. Most developers took one look and backed away slowly. Trevor Manz decided that barrier did not need to exist. His idea was simple: give Python users just enough JavaScript to unlock the web’s interactivity, without dragging along the rest of the web ecosystem. That idea became anywidget, and it is quickly becoming the quiet connective tissue of modern interactive computing. Today we dig into how it works, why it has taken off, and how it might change the way we explore data. Episode sponsors Seer: AI Debugging, Code talkpython26 PyCharm, code STRONGER PYTHON Talk Python Courses Links from the show Trevor on GitHub: github.com anywidget GitHub: github.com Trevor's SciPy 2024 Talk: www.youtube.com Marimo GitHub: github.com Myst (Markdown docs): mystmd.org Altair: altair-viz.github.io DuckDB: duckdb.org Mosaic: uwdata.github.io ipywidgets: ipywidgets.readthedocs.io Tension between Web and Data Sci Graphic: blobs.talkpython.fm Quak: github.com Walk through building a widget: anywidget.dev Widget Gallery: anywidget.dev Video: How do I anywidget?: www.youtube.com PyCharm + PSF Fundraiser: pycharm-psf-2025 code STRONGER PYTHON Watch this episode on YouTube: youtube.com Episode #530 deep-dive: talkpython.fm/530 Episode transcripts: talkpython.fm Theme Song: Developer Rap 🥁 Served in a Flask 🎸: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @talkpython@fosstodon.org X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @mkennedy@fosstodon.org Michael on X.com: @mkennedy
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    1 hr and 11 mins
  • #529: Computer Science from Scratch

    #529: Computer Science from Scratch
    Dec 3 2025
    A lot of people building software today never took the traditional CS path. They arrived through curiosity, a job that needed automating, or a late-night itch to make something work. This week, David Kopec joins me to talk about rebuilding computer science for exactly those folks, the ones who learned to program first and are now ready to understand the deeper ideas that power the tools they use every day.

    Episode sponsors

    Sentry Error Monitoring, Code talkpython26
    NordStellar
    Talk Python Courses

    Links from the show David Kopec: davekopec.com
    Classic Computer Science Book: amazon.com
    Computer Science from Scratch Book: computersciencefromscratch.com
    Computer Science from Scratch at NoStartch (CSFS30 for 30% off): nostarch.com

    Watch this episode on YouTube: youtube.com
    Episode #529 deep-dive: talkpython.fm/529
    Episode transcripts: talkpython.fm

    Theme Song: Developer Rap
    🥁 Served in a Flask 🎸: talkpython.fm/flasksong

    ---== Don't be a stranger ==---
    YouTube: youtube.com/@talkpython

    Bluesky: @talkpython.fm
    Mastodon: @talkpython@fosstodon.org
    X.com: @talkpython

    Michael on Bluesky: @mkennedy.codes
    Michael on Mastodon: @mkennedy@fosstodon.org
    Michael on X.com: @mkennedy
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    1 hr and 17 mins