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The Clinical Evidence Update

The Clinical Evidence Update

Written by: Gaurav Medikeri
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Welcome to The Clinical Evidence Update – where medical science meets everyday health decisions. Join us as we break down the latest clinical research, debunk health myths, and explore what the evidence really says about treatment, prevention, and wellness. Each episode features discussions on emerging evidence, landmark studies, and practical insights designed for both patients making informed health choices and medical professionals staying current with the latest guidelines. Hosted by an experienced ENT surgeon and healthcare leader, this podcast translates medical evidence into practice.Gaurav Medikeri Hygiene & Healthy Living
Episodes
  • Hearing loss leads to Memory loss - A Meta-analysis of Data
    Jan 12 2026

    This meta-analysis examines the strong link between age-related hearing loss and the development of dementia, specifically highlighting a linear relationship where risk increases as hearing worsens. Research involving over 700,000 participants reveals that even mild hearing impairment significantly elevates the hazard for cognitive decline, with the 25-decibel mark identified as a critical threshold for intervention. The study explores various biological and social explanations for this connection, such as increased cognitive load, social isolation, and shared genetic vulnerabilities like the APOE ε4 allele. Crucially, the data suggests that using hearing aids or cochlear implants can reduce the risk of long-term cognitive deterioration by approximately 19%, with even greater benefits for high-risk individuals. Ultimately, the authors advocate for integrating early auditory screening and restorative treatments into standard dementia prevention protocols to mitigate this major modifiable risk factor.

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    34 mins
  • Antrochoanal polyp in Children - A detailed Guide to management
    Jan 3 2026

    This Podcast offers a comprehensive analysis of antrochoanal polyps in pediatric patients, specifically focusing on their origin, surgical management, and prevention of recurrence. The sources suggest that these benign growths likely stem from chronic inflammation rather than allergies, often starting as a cyst within the maxillary sinus. Functional endoscopic sinus surgery (FESS) is identified as the primary treatment, though adding a transcanine approach or using topical Mitomycin C can significantly lower the risk of the polyp returning. Success in surgery depends heavily on completely identifying and removing the polyp’s attachment site and its surrounding periosteum. Postoperative care, including nasal irrigation and steroid treatments, is highlighted as essential for proper healing and long-term monitoring. Together, these documents provide a clinical roadmap for achieving optimal outcomes and minimizing the need for repeat operations in children.

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    42 mins
  • Music in the OR - An Evidence based Analysis of Patient Safety Vs Mood elevation
    Jan 1 2026

    Scientific evidence suggests that music in the operating room significantly enhances surgical performance, mood, and stress reduction, though it requires careful management to avoid communication risks. While classical music is objectively linked to higher task accuracy and speed, most surgeons actually prefer rock or pop, highlighting that personal familiarity is a vital factor in maintaining a calm "flow state." The provided text emphasizes that the benefits of an improved soundscape are best realized when volume remains below 60 dB and teams use protocols to silence music during critical surgical moments. Interestingly, music acts as a non-pharmacologic intervention capable of suppressing stress hormones like cortisol in both doctors and patients. However, a "communication paradox" exists where music may help an individual surgeon’s focus while simultaneously making it five times more likely that staff will misunderstand or miss verbal instructions. Ultimately, the sources advocate for treating music like a strategic tool that must be balanced with the safety needs of the entire medical team.

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    35 mins
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