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Recorded live at the Put Data First AI conference in Hollywood, Las Vegas, this episode of The Signal Room features a deep conversation between Chris Hutchins and Asha Mahesh, an expert in AI ethics, ethical leadership, and responsible data use in healthcare. The discussion goes beyond hype to examine what it truly means to humanize AI for care and build trust through ethical leadership and sound AI strategy.
Asha shares her personal journey into ethics and technology, shaped by lifelong proximity to healthcare and a commitment to ensuring innovation serves patients, clinicians, and communities. Together, they explore how ethical AI in healthcare is not just a policy document, but a way of working embedded into culture, incentives, and daily decision-making.
Key themes include building trust amid skepticism, addressing fears of job displacement, and reframing AI adoption through a 'what's in it for you' lens. Real-world examples from COVID vaccine development show how AI, guided by purpose and urgency, can accelerate clinical trials without sacrificing responsibility.
The conversation also discusses human-in-the-loop systems, the irreplaceable roles of empathy and judgment, and the importance of transparency and humility in healthcare leadership. This episode is essential listening for healthcare leaders, life sciences professionals, and AI practitioners navigating the ethical crossroads of trust and innovation.
Chapters with Keyword-Rich Descriptions
00:00 – Live from Put Data First: Why AI Ethics Matters in Healthcare
Chris Hutchins opens the conversation live from the Put Data First AI conference in Las Vegas, framing why ethics, privacy, and trust are amplified challenges in healthcare and life sciences.
01:05 – Asha’s Path into AI Ethics, Privacy, and Life Sciences
Asha shares her personal journey into healthcare technology, data, and AI ethics, shaped by early exposure to hospitals, science, and real-world impact.
03:00 – Human Impact as the North Star for Healthcare AI
Why improving patient outcomes, not technology novelty, must guide AI strategy, data science, and innovation decisions in healthcare.
04:30 – Humanizing AI for Care: Purpose Before Technology
A discussion on what “human-centered AI” really means and how intention and intended use define whether AI helps or harms.
06:20 – Embedding Ethics into Culture, Not Policy Documents
Why ethical AI is not a checklist or white paper, but a set of behaviors, incentives, and ways of working embedded into organizational culture.
07:55 – COVID Vaccine Development: AI Done Right
A real-world example of how data, machine learning, and predictive models accelerated clinical trials during the pandemic while maintaining responsibility.
10:15 – Mission Over Technology: Lessons from the Pandemic
How urgency, shared purpose, and collaboration unlocked innovation faster than tools alone, and why that mindset should not require a crisis.
12:20 – The Erosion of Trust in Institutions and Technology
Chris reflects on declining trust in government, healthcare, and technology, and why AI leaders must now operate from a trust deficit.
14:10 – Fear and AI: Addressing Job Loss Concerns
A practical conversation on why fear of AI replacing jobs persists and how leaders can reframe AI as support, not replacement.
16:30 – “What’s In It for You?” A Human-Centered Adoption Framework
How focusing on individual value, workflow relief, and personal benefit increases trust and adoption of AI tools in healthcare and life sciences.
18:00 – How Human Should AI Be?
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