In this week’s episode of the Xtalks Life Science Podcast, host Ayesha Rashid, Senior Life Science Journalist at Xtalks, spoke with Joseph Sinkule, CEO, Founder and the Chairman of the Board of Directors at Klotho Neurosciences, a biogenetics company developing cell and gene therapies using a patented, secreted form of the “anti-aging” human α-Klotho gene for the treatment of neurodegenerative, age-related disorders such as Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), Parkinson’s disease and others.

Dr. Sinkule has over 40 years of drug, biologic and medical device R&D and commercialization experience. He has managed over eight drug and biotech products successfully through FDA approval to market, as well as five medical devices and eight in vitro diagnostics.

After serving in academics and then in industry, Dr. Sinkule has evolved into a successful businessman and entrepreneur. He has led teams of all sizes, managed CROs and CDMOs, serves on two company boards and regularly advises venture capital firms, investment banks and pharmaceutical and biotech companies at all stages.

Tune in to learn more about targeting pathways of aging in diseases like Alzheimer’s and ALS.

For more life science and medical device content, visit the Xtalks Vitals homepage. https://xtalks.com/vitals/

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In this week’s episode of the Xtalks Life Science Podcast, host Ayesha Rashid, Senior Life Science Journalist at Xtalks, spoke with Ahmed Enayetallah, PhD, MBBCh, Chief Development Officer at Dompé Farmaceutici, a company founded as the first compounding pharmacy in Milan, Italy, which has grown into a global biopharmaceutical company over 130 years.

Currently, the company has a therapeutic pipeline focused on nerve growth factor (NGF)-based therapeutics in ocular diseases, including non-arteritic anterior ischemic optic neuropathy (NAION). Dompé has been a pioneer in translating NGF biology into medicine, building on decades of research by Nobel laureate Dr. Rita Levi-Montalcini.

Dr. Enayetallah has a robust background in clinical research and deep expertise in drug development. His career has spanned several high-profile leading roles at pharmaceutical and biotechnology companies such as Amgen, Biogen, Pfizer and Alexion. He has led efforts in personalized medicine and oversaw multiple successful clinical programs that brought novel therapies to patients with high unmet needs. Prior to joining Dompé, he led the development organization at BlueRock Therapeutics.

Dr. Enayetallah earned his medical degree from the University of Cairo and completed his PhD in Pharmacology and Toxicology at the University of Connecticut.

Tune in to learn more about NGF biology and how it is being leveraged therapeutically in ocular diseases with high unmet need.

For more life science and medical device content, visit the Xtalks Vitals homepage. https://xtalks.com/vitals/

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In this week’s episode of the Xtalks Life Science Podcast, host Ayesha Rashid, Senior Life Science Journalist at Xtalks, spoke with Jason Matuszewski, chairman, CEO and co-founder of BioStem Technologies, a company developing perinatal tissue allografts for regenerative therapies.

The applications of the allografts, developed using the company’s proprietary processing method, include wound care, limb saving in conditions like diabetic foot ulcers and treating wounds and amputations of veterans.

After beginning his career as a technical engineer at SC Johnson and later leading process and quality initiatives at companies like ATI Ladish Forging, Nemak and HUSCO International, Jason’s work with the Juvenile Diabetes Research Foundation inspired his move into biotech. At BioStem, he’s overseen optimized tissue sourcing, the build-out of a 6,000-square-foot, fully FDA- and AATB-compliant tissue processing facility and the growth of a high-performing team.

Jason has a Bachelor of Science (BS) in Mechanical Engineering Technology, is a Six Sigma Black Belt and serves on the AATB Processing and Distribution Council and BioFlorida’s Government Affairs Committee.

Tune in to learn more about cutting edge developments in regenerative medicine and wound care.

For more life science and medical device content, visit the Xtalks Vitals homepage. https://xtalks.com/vitals/

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Twitter: https://twitter.com/Xtalks Instagram: https://www.instagram.com/xtalks/ Facebook: https://www.facebook.com/Xtalks.Webinars/ LinkedIn: https://www.linkedin.com/company/xtalks-webconferences YouTube: https://www.youtube.com/c/XtalksWebinars/featured