When Oliver Sacks was 12 years old, a perceptive schoolmaster wrote in his report: "Sacks will go far, if he does not go too far." It is now abundantly clear that Sacks has never stopped going. From its opening reflection on his youthful obsession with motorcycles and speed, On the Move is infused with his restless energy.

As he recounts his experiences as a young neurologist in the early 1960s, first in California and then in New York, where he discovered a long-forgotten illness in the back wards of a chronic hospital, as well as with a group of patients who would define his life, it becomes clear that Sacks' earnest desire for engagement has occasioned unexpected encounters and travels - sending him through bars and alleys, over oceans, and across continents.

With unbridled honesty and humour, Sacks shows us that the same energy that drives his physical passions - bodybuilding, weightlifting, and swimming - also drives his cerebral passions. He writes about his love affairs, both romantic and intellectual, his guilt over leaving his family to come to America, his bond with his schizophrenic brother, and the writers and scientists - Thom Gunn, A. R. Luria, W. H. Auden, Gerald M. Edelman, Francis Crick - who influenced him.

On the Move is the story of a brilliantly unconventional physician and writer - and of the man who has illuminated the many ways that the brain makes us human.