On Halloween night, 1828, in the West Port district of Edinburgh, Scotland, a woman sometimes known as Madgy Docherty was last seen in the company of William Burke and William Hare. Days later, police discovered her remains in the surgery of the prominent anatomist Dr. Robert Knox. Docherty was the final victim of the most atrocious murder spree of the century, outflanking even Jack the Ripper's.

Together with their accomplices, Burke and Hare would be accused of killing 16 people over the course of 12 months in order to sell the corpses as "subjects" for dissection. The ensuing criminal investigation into the "Anatomy Murders" raised troubling questions about the common practices by which medical men obtained cadavers, the lives of the poor in Edinburgh's back alleys, and the ability of the police to protect the public from cold-blooded murder.

Famous among true crime aficionados, Burke and Hare were the first serial killers to capture media attention, yet The Anatomy Murders is the first book to situate their story against the social and cultural forces that were bringing early 19th-century Britain into modernity. In Lisa Rosner's deft treatment, each of the murder victims, from the beautiful, doomed Mary Paterson to the unfortunate "Daft Jamie", opens a window on a different aspect of this world in transition.