In this episode of “Cognitive Conversations,” expert faculty discuss breaking data presentations from the 2026 Clinical Trials on Alzheimer’s Disease conference held in San Diego, California, from December 1-4, 2025, and their implications for clinical practice.

Topics covered include:

• Evoke and evoke+ phase III trials of semaglutide
• Subcutaneous lecanemab as initiation and maintenance treatment
• Blood-based biomarker assays
• Trontinemab and other brain shuttles
• Tau targeting therapies in development
• Preventive impact of BCG and herpes zoster vaccination

This podcast episode is part of the CME/CE-accredited program, “Early Clues, Lasting Impact: Detecting and Treating Alzheimer’s Disease in Its Earliest Stages,” supported by an educational grant from Novo Nordisk.

Faculty:

Anton P. Porsteinsson, MD
William B. and Sheila Konar Professor of Psychiatry, Neurology, and Neuroscience, and Medicine
Director, Alzheimer's Disease Care, Research and Education Program (AD-CARE)
University of Rochester School of Medicine and Dentistry
Rochester, New York

Vijay K. Ramanan, MD, PhD
Consultant and Associate Professor
Director, Alzheimer’s Disease Treatment Clinic
Department of Neurology
Mayo Clinic
Rochester, Minnesota

Link to obtain CME/CE credit:
https://bit.ly/4999otE

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In this podcast episode, epilepsy specialists Danielle Becker, MD, MS, FAES, and Sarah Weatherspoon, MD, discuss the personalization of the most recently available epilepsy rescue treatments for younger kids and their implementation by the patient care team.

Faculty:

Danielle Becker, MD, MS, FAES
Division Director of Epilepsy
Associate Professor of Neurology
The Ohio State University Wexner Medical Center
Columbus, Ohio

Sarah Weatherspoon, MD
Associate Chief of Child Neurology
Tuberous Sclerosis Center of Excellence, Neurology Co-Director
Le Bonheur Children's Hospital
University of Tennessee Health Science Center
Memphis, Tennessee

Resources mentioned in this episode:

• Epilepsy Foundation Seizure Action Plan Toolkit
• CDC Managing Epilepsy Well (MEW) Network

Link to Brain Health Hub with additional educational activities:
https://bit.ly/3Y12Isx

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode, Alireza Atri, MD, PhD, discusses his approach to patient conversations on brain health and provides advice to healthcare professionals practicing in community neurology settings, in a dialogue with Robin Martinez, a patient advocate from the Smart Patients online community. Supported by an educational grant from Lilly.

Faculty:

Alireza Atri, MD, PhD
Chief Medical Officer, Banner Research
Phoenix, Tucson and Sun City, Arizona
Director, Banner Sun Health Research Institute
Sun City, Arizona

Robin Martinez
Patient Advocate
Coordinator of Online Communities
Website Administration
Smart Patients Inc.
Denver, Colorado

Resources mentioned in this episode:

• Alzheimer’s Association: DETeCD-ADRD Clinical Practice Guidelines for Specialty Care
  https://bit.ly/4kqtYt5
• American Geriatrics Society: 2023 Beers Criteria for Potentially Inappropriate Medication Use in Older Adults
  https://bit.ly/44zN8qG
• MoCA (Montreal Cognitive Assessment) : [Link to: https://mocacognition.com/]

Link to obtain CME/CE credit:
https://bit.ly/44khuP5

Link to Brain Health Hub with additional educational activities:
https://bit.ly/4kziu6T

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.