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Peanut allergies have been significantly averted in U.S. children due to a major shift in medical guidance. A landmark 2015 study, the LEAP trial, found that introducing peanut products to infants as early as 4 to 6 months reduced the risk of developing a peanut allergy by over 80%.
This led to updated national guidelines in 2017 and 2021 recommending early allergen introduction without prior testing.

Recent research confirms the real-world impact:

• A study published in Pediatrics found a 43% reduction in peanut allergies among children under 3 after the guidelines were implemented.
  
  
• Another analysis estimates that tens of thousands of children—up to 60,000—have avoided peanut allergies thanks to early introduction.
  
  
• The overall rate of food allergies in young children dropped by 36%, with peanut allergies no longer the top cause of food allergy in children under 3.
  
  

Early introduction is now the standard of care:

• No need for screening: The current guidance advises introducing peanuts and other major allergens between 4 and 6 months, even for high-risk infants, without prior testing.
• Safe methods: Parents can offer small amounts of peanut butter, peanut flour, or peanut-containing yogurt.
• Key message: Early, consistent exposure helps train the immune system to tolerate peanuts, preventing allergy development.
  
  

While prevention is now possible for many, treatment options exist for those already allergic, including oral immunotherapy (like Palforzia) and emerging therapies such as sublingual patches and experimental mRNA-based nanoparticles.
However, these are not cures—they build tolerance or reduce reaction severity—and should be managed under medical supervision.

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