Learn how RevealDX uses AI and radiomics to characterize lung nodules, reduce false positives, and accelerate early cancer detection in this expert interview.

Episode Resources

• RevealDX
• The Fleischner Society
• ACR Lung-RADS
• National Lung Screening Trial (NLST)
• I-ELCAP Research
• HeartFlow

Lung nodules are one of the most common "incidentalomas" found in modern imaging, yet the path from detection to diagnosis is often fraught with patient anxiety and unnecessary biopsies. In this episode, we are joined by Chris Wood, the CEO of RevealDX, to discuss how his company is revolutionizing the diagnostic process. By using advanced AI to move beyond simple detection and into precise characterization, the platform helps clinicians distinguish between benign spots and high-risk malignancies before invasive procedures are required.

Chris shares his journey as a serial entrepreneur and details the rigorous process of building clinical evidence for AI-driven tools. We explore the critical role of radiomics in identifying subtle features invisible to the human eye and the complex landscape of health tech reimbursement. The conversation also covers how these tools can streamline hospital workflows, support overburdened radiologists, and ultimately improve the success rate of early cancer detection programs by catching malignancies when they are most treatable.

If you are a clinician, hospital administrator, or health tech founder looking to understand how to bridge the gap between innovative algorithms and routine clinical practice, this episode is essential listening. Chris provides a masterclass in navigating the "second wave" of healthcare technology, focusing on sustainable business models and measurable patient outcomes. Learn how a risk-adapted approach to lung nodules can save lives while reducing the burden on an overstretched healthcare system.

Learn how athenahealth is building the AI-native EHR to reduce clinician burnout. Paul Brient shares insights on ambient dictation and revenue cycle management.

Episode Resources

• athenaOne: All-in-One Health Software
• Paul Brient, Chief Product Officer Profile
• athenahealth Ambient Notes

Traditional electronic health records often feel like a digital burden rather than a helpful tool. Paul Brient, Chief Product and Operations Officer at athenahealth, joins the show to discuss how they are transforming the industry by building an AI-native EHR designed specifically for the modern ambulatory setting.

Paul shares the evolution of athenahealth from an OBGYN startup to a multi-billion dollar platform supporting 170,000 providers. We explore how ambient dictation is moving beyond simple transcription to automate clinical orders and significantly reduce clinician burnout. By leveraging data-driven insights, athenahealth is helping independent practices remain competitive through streamlined revenue cycle management and integrated patient engagement tools.

If you are a healthcare leader or clinician looking to reclaim your "pajama time" and understand the future of clinical documentation, this episode is for you. Learn how to navigate the AI hype cycle and implement technology that offers real, incremental value to your daily workflow.

Is the EHR causing physician burnout? Wellsheet CEO Craig Limoli joins HealthTech Remedy to discuss reducing "pajama time," integrating UpToDate, and using AI to transform clinical documentation.

Episode Resources:

• Learn more about Wellsheet
• Follow Craig Limoli on LinkedIn
• Details on the Wellsheet & UpToDate Partnership

In this episode of HealthTech Remedy, hosts Dr. Tim Showalter, Dr. Paul Gerrard, and Dr. Trevor Royce dive into one of the most persistent frustrations in modern medicine: the burden of the Electronic Health Record (EHR). We sit down with Craig Limoli, Co-founder and CEO of Wellsheet, to discuss how his company is tackling the dreaded "pajama time" - the hours physicians spend charting late at night - not by replacing the EHR, but by fixing how clinicians interact with it. If you’ve ever felt buried under thirty open tabs while trying to find a single lab result, this conversation is for you.

Craig breaks down Wellsheet’s unique approach as an intelligent "layer" that sits on top of existing systems like Epic and Cerner. We explore how their predictive workflow technology consolidates fragmented patient data into a single, intuitive view, and discuss their game-changing partnership with UpToDate that brings clinical guidelines directly into the decision-making process. The discussion also covers their latest AI advancements, including an agent that allows doctors to "chat" with a patient's chart to retrieve data instantly and features that automate inpatient documentation to save hours of manual work.

Finally, we look ahead to the "healthcare utopia of 2030." We discuss why smarter collaboration tools are essential for solving the looming clinical workforce shortage and how responsible AI can reduce burnout while improving patient safety. Whether you are a healthcare executive, a practicing clinician, or a tech enthusiast, this episode offers a pragmatic look at how intelligent workflows are reshaping the future of care delivery.

About Our Guest:

Craig Limoli is the Co-Founder and CEO of Wellsheet, a company on a mission to fix the usability crisis in healthcare technology. His journey began as a strategy consultant at IBM's Watson Health, where he witnessed firsthand the immense frustration clinicians faced with antiquated and inefficient EHR systems. Motivated by a nursing leader who broke down in tears over her inability to access the data needed to treat her patients, Craig left to build the solution himself. Wellsheet was born from this experience, with the goal of creating a single, intelligent "sheet" that synthesizes all relevant data for clinical decision-making.

Timestamps:

(00:00) Introduction: The Problem with Medical Charting

(02:56) Defining the Crisis: EHRs, "Pajama Time," and Clinician Burnout

(04:51) Wellsheet's Strategy: An Intelligent Layer, Not a New EHR

(08:28) Improving Care Team Collaboration and ROI for Health Systems

(13:25) Meet the Founder: Craig Limoli's Journey from IBM to Wellsheet

(17:58) The Strategic Advantage of Integrating With, Not Replacing, the EHR

(20:55) Product Deep Dive: How AI Summarizes Data and Automates Documentation

(25:21) Enhancing Workflows with Clinical Decision Support (UpToDate Integration)

(32:22) The Business Model: Selling to Clinicians and Hospital Executives

(34:31) Building Guardrails for AI in Healthcare

(37:24) The Future Vision for a Productive and Efficient Healthcare System

How does a pharmacist become a venture capitalist? Hear Meg Powell's story on the transition from big pharma to startup and her advice for women in healthcare leadership.

Episode resources:

• Learn about 501 Ventures
• Follow Meg Powell on LinkedIn

Have you ever wondered if your clinical training could lead to a career in high-stakes investing? This episode charts the incredible journey of Meg Powell, who forged a unique path from pharmacist to venture capitalist. Meg shares the invaluable lessons, pivotal moments, and scrappy determination that took her from a small town in North Carolina to the executive suites of Big Pharma, the trenches of a successful startup, and finally to the helm of her own venture capital firm. We explore the core question: How do you build a multifaceted career in healthcare, and what does it truly take to transition from clinician to entrepreneur to investor?

In this deep-dive conversation, Meg Powell, co-founder and CEO of 501 Ventures, reveals the playbook for navigating a dynamic career in the life sciences. She details her foundational years at Eli Lilly and GSK, explaining why a transition from big pharma to startup life provided her with indispensable training and an unparalleled network. Meg walks us through the origin story of Target RWE, a pioneering real world evidence company she co-founded with Dr. Mike Freed. She shares the challenges of building a profitable company from the ground up with minimal funding, the importance of finding the right co-founder, and the strategy behind their successful exit. We also learn about her experience with imposter syndrome and how being a "scrappy entrepreneur" became her greatest asset.

Now, Meg is focused on the next frontier of medicine through healthcare venture capital. She discusses the formation of 501 Ventures with her partner Enrique Conterno (former President of Lilly Diabetes) and their investment thesis in the booming metabolic health and obesity market, fueled by innovations like Tirzepatide (Zepbound). A significant part of our discussion is dedicated to women in healthcare leadership. Meg speaks candidly about the "aha moments" that ignited her passion for mentorship, the challenges she faced, and how she is paying it forward with "The Fierce Collaborative," a network dedicated to supporting women and mothers in the life sciences. This episode is packed with authentic career advice, insights into the future of healthcare investing, and the inspiring story of a leader who has consistently broken new ground.

About our guest:

Meg Powell is the Co-founder and CEO of 501 Ventures, a venture capital firm focused on metabolic health. A PharmD by training, Meg began her career in Big Pharma at Eli Lilly and GlaxoSmithKline before transitioning to the startup world. She was the co-founder and CEO of Target RWE, a leading real-world evidence company that she grew from an idea to a highly successful exit. Meg is a passionate advocate for women in leadership and a mentor to the next generation of healthcare entrepreneurs.

Most doctors have brilliant ideas, but why do 98% of them fail before they ever reach a patient? The brutal truth is that a clinical mindset is not an entrepreneurial mindset, and the skills that make a great doctor are not the same ones that build a successful company. In this episode, we sit down with the ultimate physician entrepreneur, Dr. Arlen Meyers, to uncover the harsh realities of medical innovation and why your great idea is probably destined to fail without a fundamental shift in thinking.

Dr. Meyers, an academic surgeon turned serial entrepreneur, shares his own frustrating journey as an "accidental med-tech entrepreneur" trying to commercialize a cancer-detecting gadget. This experience revealed a massive gap in medical education: the complete lack of training in the business of medicine. This gap inspired him to create the Society of Physician Entrepreneurs (SoPE), a global network dedicated to helping clinicians navigate the treacherous path from idea to impact. We explore the critical need for doctors to develop an entrepreneurial mindset, whether they are launching a startup, pioneering medical innovation within a hospital (as an "intrapreneur"), or considering a physician career change. Dr. Meyers provides a clear definition of what it truly means to be a physician entrepreneur, arguing that it's a mindset that can be developed, not just an innate trait. He introduces the concept of the "innerpreneur"—the hidden innovator DNA that many clinicians possess but don't know how to activate. We also discuss why he believes most MD-MBA programs are a "bad idea" and why teaching the business of medicine must be integrated directly into medical school. Finally, Dr. Meyers explains the mission of the Society of Physician Entrepreneurs and offers his most important piece of advice for any doctor pursuing an entrepreneurial role: "make it personal, but don't take it personally."

About Our Guest:

Dr. Arlen Meyers is an academic surgeon, professor, MD, and MBA who became frustrated by the lack of entrepreneurial support for clinicians. He is the founder of the Society of Physician Entrepreneurs (SoPE), a global non-profit organization that provides education, resources, and networking to help physician innovators get their ideas to patients. After a long career in academic medicine, he now dedicates his time to teaching, writing, and consulting to bridge the gap between medicine and entrepreneurship.

Chapters:

(00:00) Why Most Medical Ideas from Doctors Are Doomed to Fail

(01:37) Dr. Meyers' Journey: From Accidental Med-Tech Entrepreneur to Innovator

(06:09) Defining the Physician Entrepreneur and the "Innerpreneur" Mindset

(12:06) The Critical Gap in Medical Education: The Business of Medicine

(18:24) The Creation of the Society of Physician Entrepreneurs (SoPE)

(21:37) The Forgotten Skill: Why Physician Entrepreneurs Must Learn to Sell

(25:23) The Future of the Physician Entrepreneur Ecosystem

(29:01) Final Advice: Making It Personal, But Not Taking It Personally

Episode Resources:

• Learn more about the Society of Physician Entrepreneurs (SoPE)
• Read Dr. Meyers' articles on Substack
• Connect with Dr. Meyers on LinkedIn

Is the traditional academic path failing doctors who want to innovate? For many physicians, the dream of impacting patient care on a massive scale feels out of reach within the slow-moving world of grants and publications. This episode explores the alternative: the dynamic and rapidly evolving physician career paths in health tech. We're joined by Dr. Shrujal Baxi, a physician executive and former Chief Medical Officer at Iterative Health, who shares her incredible journey from being a top medical oncologist at Memorial Sloan Kettering to becoming a leader at pioneering tech companies like Flatiron Health, Verana Health, and Iterative Health.

Dr. Baxi reveals the critical moment she realized academic research, despite its rigor, couldn't deliver solutions at the speed technology could. This conversation is a masterclass for any doctor questioning their career trajectory, offering a candid look at the challenges and rewards of transitioning from the clinic to the tech industry. We dive deep into how her skills as a clinician became her greatest asset in corporate settings, the pivotal role of real-world evidence in shaping modern medicine, and the future of AI in medicine. If you've ever wondered how to commercialize a great idea to truly help patients or what the role of clinicians in tech companies truly entails, this discussion provides the roadmap. Dr. Baxi breaks down her experience working on everything from large-scale data sets in oncology to using computer vision for endoscopy in gastroenterology, demonstrating the vast opportunities available for physicians outside of traditional practice. This episode isn't just a story; it's a guide to forging impactful physician career paths in health tech, exploring the academia vs industry for physicians debate, and understanding how to build a scalable solution that changes patient lives.

ABOUT OUR GUEST:

Dr. Shrujal Baxi is a physician executive who has built a remarkable career at the intersection of medicine and technology. After training as a medical oncologist and conducting health services research at the world-renowned Memorial Sloan Kettering Cancer Center, she made the leap to industry. She has held leadership roles at some of the most influential companies in health tech, including Flatiron Health, Verana Health, and most recently as Chief Medical Officer of Iterative Health. Dr. Baxi shares her unique perspective on leveraging real-world evidence and AI in medicine to drive innovation and improve patient outcomes.

TIMESTAMPS / CHAPTERS:

(00:00) The Rise of Physician Innovators in Health Tech

(01:40) Dr. Baxi's Origin: From Oncology to Health Services Research

(05:51) The Turning Point: Why Academic Research Moves Too Slowly

(08:49) Making the Leap to Flatiron Health & a New Career Path

(12:46) The Untapped Value of Clinicians in Tech Companies

(17:43) Scaling Real-World Evidence Beyond Oncology at Verana Health

(21:31) Pioneering AI in Medicine with Computer Vision at Iterative Health

(25:32) The Future of Health Tech & Early-Stage Innovation

(28:48) Dr. Baxi's Advice for Aspiring Physician Innovators

Episode Resources:

• Connect with Dr. Shrujal Baxi
• Learn more about Flatiron Health
• Learn more about Verana Health
• Learn more about Iterative Health

Is a "normal" mammogram result enough to truly protect your health? What if your standard scan is missing crucial information that could predict your risk for both breast cancer and heart disease years in advance? This episode challenges the one-size-fits-all approach to medical imaging and explores the future of AI in radiology for personalized patient care. We uncover how machine learning is moving healthcare from a reactive model to a proactive one, where diseases are caught earlier and treatments are tailored to the individual, not the average.

In this installment of our Physician Innovators series, host Dr. Trevor Royce sits down with Dr. Sean Raj, a practicing radiologist and the Chief Innovation Officer and Chief Medical Officer at SimonMed Imaging. Dr. Raj breaks down how his team is pioneering this shift at one of the largest outpatient imaging practices in the nation. We dive deep into SimonMed's groundbreaking programs, which are redefining what patients can learn from a single imaging session. Dr. Raj explains the revolutionary "Mammogram Plus" program, which provides a highly personalized breast cancer screening by analyzing not just the image, but a patient's individual risk factors like breast density to provide actionable insights. We also explore the incredible innovation of detecting heart disease from mammograms—a capability that leverages the same scan to identify early signs of breast arterial calcifications, giving women a powerful two-for-one look at their health. The conversation also turns to the rising trend of proactive health screening with the whole body MRI for early detection. Dr. Raj details SimonMed's "simonONE" program, which utilizes advanced 3-Tesla MRI machines and AI to conduct comprehensive scans in as little as 30 minutes, finding silent diseases years before symptoms might appear. Throughout the discussion, Dr. Raj emphasizes the benefits of AI in medical imaging, from enhancing radiologist performance to making advanced diagnostics more affordable and accessible. This episode is a must-watch for anyone interested in the future of medicine, technology, and for aspiring physician innovators in health tech looking to make a scalable impact on patient outcomes.

About Our Guest:

Dr. Sean Raj is the Chief Innovation Officer at SimonMed Imaging. A practicing radiologist who completed his breast imaging fellowship at Harvard Medical School's Beth Israel Deaconess Medical Center, Dr. Raj is dedicated to integrating cutting-edge technology into clinical practice. He leads SimonMed's initiatives in evaluating and implementing new technologies like artificial intelligence, developing patient-centered research programs, and making proactive healthcare accessible and affordable on a national scale.

Timestamps:

(00:00) Introduction to Physician Innovators & Dr. Sean Raj

(02:20) Dr. Raj's Journey: From Medicine to Health Tech Innovation

(06:12) Mammogram Plus: Using AI for Personalized Breast and Heart Health

(11:02) Measuring Success: Patient Outcomes, Experience, and Scalability

(12:01) The Radiologist's Experience: Integrating AI into the Clinical Workflow

(15:52) Proactive Health Screening with the simonONE Whole Body MRI

(19:19) Balancing Innovation, Affordability, and Patient Access

(21:10) Enhancing Patient Understanding with Digital, Digestible Reports

(25:32) The Future of Radiology: Towards Proactive and Hyper-Personalized Care

(27:22) Advice for Aspiring Physician Innovators

Learn More From Our Guest / Episode Resources:

• Learn more about SimonMed Imaging
• Explore the simonONE Whole Body MRI
• Discover Mammogram Plus and Mammogram Plus Heart
• Check out Cascaid Health's digital reports