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Hope Through Engineering: Transcatheter Heart Repair with Dr. Raj Makkar cover art

Hope Through Engineering: Transcatheter Heart Repair with Dr. Raj Makkar

Hope Through Engineering: Transcatheter Heart Repair with Dr. Raj Makkar

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Episode: #5

Guest: Dr. Raj Makkar

Topics: Transcatheter Therapy | Heart Valve Repair | Heart Valve Replacement

When you’ve been told you’re 'too complex' or 'too high-risk' for surgery, it can feel like the door has been slammed shut. Today, we’re opening that door back up."


For decades, fixing a heart valve meant open-heart surgery—a high-risk prospect for survivors whose bodies have already been through the fires of radiation or chemotherapy. But cardiac care has been transformed. In this episode, host Mary Burrell is joined by Dr. Raj Makkar, a world-renowned expert at the Smidt Heart Institute at Cedars-Sinai, to discuss the evolution of transcatheter valve therapies.


With a career defined by over 5,000 procedures, Dr. Makkar is at the forefront of repairing and replacing the heart’s "plumbing" from the inside out. We explore how these minimally invasive techniques provide a safer, faster path to recovery for those whose medical histories make traditional surgery a challenge.


Strategic Insights from This Episode:

  • The Power of Minimally Invasive Care: Why a catheter-based repair or replacement is often the safest choice for a survivor with "fragile" or radiation-scarred anatomy.
  • Faster Recovery, More Time: How moving away from "the zipper scar" allows survivors to get back to their lives without the months-long recovery of traditional surgery.
  • Rejecting the "Too Complex" Label: Dr. Makkar’s advice for patients who have been sidelined by the medical system and told there is no hope for a fix.
  • The Specialist Connection: How to ensure your cardiologist understands the link between your cancer history and your valve health so nothing gets missed.

If the system has told you "no," this conversation is about finding the specialist who can say "yes."


Tune in to shift the narrative from fragmented survival to strategic advocacy. Let’s build the bridge the system forgot.


Clinical Resources:

The Structural Blueprint: Cedars-Sinai: Heart Valve Disease Guide — A clear explanation of heart valve mechanics and how to identify the signs of structural failure.

The Science of Survival: A deep-dive into how past cancer treatments "reprogram" the heart’s metabolism and the dormant cellular changes—like oxidative stress and fibrosis—that can lead to valve failure decades late


Explore the Whole Picture:

Learn more about our Guest: Dr. Raj Makkar

Visit our Website: ⁠https://www.maryburrell.com

Connect with Us: info@maryburrell.com

Subscribe to the Show: ⁠Heart2Heart Talk


Championing the whole heart—yours, ours and theirs.

#Heart2HeartTalk ##HeartValveRepair #HeartValveReplacement #CardioOncology #StructuralHeart #PatientAdvocacy #CedarsSinai



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