Flesh & Bones in English cover art

Flesh & Bones in English

Flesh & Bones in English

Written by: Lorenzo Fatto Offidani
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Medicine in human terms: the art and science of being alive.

What happens beneath our skin? How does the human body maintain its balance, respond to disease, and adapt to the world around us?

Flesh&Bones explores anatomy, physiology, pathology, and clinical reasoning through accessible, evidence-informed storytelling. Each episode takes a complex medical concept and makes it understandable without sacrificing the scientific details that matter.

Created for medical students, healthcare professionals, and anyone curious about the human body, the podcast connects fundamental biological mechanisms with the human experience of health and illness.

This English edition accompanies Flesh&Bones en Español, offering equivalent educational content across two languages. Together, the editions also provide an opportunity to explore and compare medical terminology in English and Spanish.

Flesh&Bones provides educational information and does not replace professional medical advice, diagnosis, or treatment.

© 2026 Lorenzo Fattò Offidani. All rights reserved.
Episodes
  • A Heart in Crisis: Understanding Myocardial Infarction

    A Heart in Crisis: Understanding Myocardial Infarction
    Oct 16 2026

    A 66-year-old man arrives at the hospital after hours of severe chest pain. What follows allows us to trace the physiology of a myocardial infarction step by step.

    We examine atherosclerosis, coronary artery obstruction, electrocardiographic changes, myocardial injury, cardiogenic shock, and mechanical complications. This clinical case illustrates why time can profoundly influence the outcome of a heart attack.

    Sources and further reading:

    1. Ribeiro WN, Yamada AT, Benvenuti LA. Case 4/2014: a 66-year-old man with acute myocardial infarction and death in asystole after primary coronary angioplasty. Arq Bras Cardiol. 2014;103(3):e31-e36. doi:10.5935/abc.20140129.
    2. Thygesen K, Alpert JS, Jaffe AS, et al. Fourth universal definition of myocardial infarction (2018). J Am Coll Cardiol. 2018;72(18):2231-2264. doi:10.1016/j.jacc.2018.08.1038.


    Educational content only. Not a substitute for individualized medical advice, diagnosis, or treatment.
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    9 mins
  • Homeostasis and Feedback Systems

    Homeostasis and Feedback Systems
    Oct 14 2026

    How does the body remain stable while everything around us changes?

    We explore homeostasis and the sensors, control centers, and effectors that regulate variables such as temperature, blood glucose, and blood pressure. We also explain negative feedback and amplifying feedback mechanisms, showing how the body constantly responds, corrects, and adapts.

    Sources and further reading:

    1. Kiesewetter A, Schmiemann P. Understanding homeostatic regulation: the role of relationships and conditions in feedback loop reasoning. CBE Life Sci Educ. 2022;21(3):ar56. doi:10.1187/cbe.21-04-0092.
    2. Hall JE, Hall ME. Guyton and Hall textbook of medical physiology. 14th ed. Philadelphia: Elsevier; 2020.


    Educational content only. Not a substitute for individualized medical advice, diagnosis, or treatment.
    Show More Show Less
    10 mins
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