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Into the Impossible With Brian Keating

Into the Impossible With Brian Keating

Written by: Big Bang Productions Inc.
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 Think like a physicist. Wonder like a human. Into the Impossible is where Cosmic Conversations happen — uniting Nobel Prize winners, iconoclasts, authors, and technologists to explore reality’s deepest questions. From AI to aliens, from biophysics to the brain, from the cosmos to the multiverse, Brian Keating, Chancellor’s Distinguished Professor of Physics at UC San Diego covers it all. If you’ve ever asked What’s out there? or What’s next?, this is where curiosity meets clarity. Learn to think like this. 🎙 Full episodes, notes & more: briankeating.com/podcast© 2025 Big Bang Productions Inc. 719843 Nature & Ecology Physics Science
Episodes
  • The Mysterious Math Behind LLMs | Anil Ananthaswamy

    The Mysterious Math Behind LLMs | Anil Ananthaswamy
    Jan 23 2026
    WANTED: Developers and STEM experts! Get paid to create benchmarks and improve AI models. Sign up for Alignerr using our link: https://alignerr.com/?referral-source=briankeating One of the most powerful AI systems we’ve ever built is succeeding for reasons we still don’t understand. And worse, they may succeed for reasons that might lock us into the wrong future for humanity. Today’s guest is Anil Ananthaswamy, an award-winning science writer and one of the clearest thinkers on the mathematical foundations of machine learning. In this conversation, we’re not just talking about new demos, incremental improvements, or updates on new models being released. We’re asking even harder questions: Why does the mathematics of machine learning work at all? How do these models succeed when they suffer from problems like overparameterization and lack of training data? And are large language models revealing deep structure, or are they just producing very convincing illusions and causing us to face an increasingly AI-slop-driven future? KEY TAKEAWAYS 00:00 — Book explores why ML works through math 02:47 — Perceptron proof shows simple math guarantees learning 05:11 — Early AI failed due to single-layer limits 07:12 — Nonlinear limits caused the first AI winter 09:04 — Backpropagation revived neural networks 10:59 — GPUs + big data enabled deep learning 15:25 — AI success risks technological lock-in 17:30 — LLMs lack human-like learning and embodiment 22:57 — High-dimensional spaces power ML behavior 27:36 — Data saturation may slow future gains 31:11 — Continual learning is still missing in AI 33:46 — Neuromorphic chips promise energy efficiency 41:49 — Overparameterized models still generalize well 45:05 — SGD succeeds via randomness in complex landscapes 48:27 — Perceptrons remain the core of modern neural net - Additional resources: Anil's NEW Book "Why Machines Learn: The Elegant Math Behind Modern AI": https://www.amazon.com/Why-Machines-Learn-Elegant-Behind/dp/0593185749 Get My NEW Book: Focus Like a Nobel Prize Winner: https://www.amazon.com/dp/B0FN8DH6SX?ref_=pe_93986420_775043100 Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥 - Join this channel to get access to perks like monthly Office Hours: https://www.youtube.com/channel/UCmXH_moPhfkqCk6S3b9RWuw/join 📚 Get a copy of my books: Think Like a Nobel Prize Winner, with life changing interviews with 9 Nobel Prizewinners: https://a.co/d/03ezQFu My tell-all cosmic memoir Losing the Nobel Prize: http://amzn.to/2sa5UpA The first-ever audiobook from Galileo: Dialogue Concerning the Two Chief World Systems: Ptolemaic and Copernican https://a.co/d/iZPi9Un 📺 Watch my most popular videos:📺 Neil Turok https://www.youtube.com/watch?v=Dt5cFLN65fI Frank Wilczek https://youtu.be/3z8RqKMQHe0?sub_confirmation=1 Eric Weinstein vs. Stephen Wolfram https://www.youtube.com/watch?v=OI0AZ4Y4Ip4?sub_confirmation=1 Sir Roger Penrose: https://youtu.be/AMuqyAvX7Wo Sabine Hossenfelder: https://youtu.be/g00ilS6tBvs Avi Loeb: https://youtu.be/N9lUceHsLRw Follow me to ask questions of my guests: 🏄‍♂️ Twitter: https://twitter.com/DrBrianKeating 🔔 Subscribe https://www.youtube.com/DrBrianKeating?sub_confirmation=1 📝 Join my mailing list; just click here http://briankeating.com/list ✍️ Detailed Blog posts here: https://briankeating.com/blog 🎙️ Listen on audio-only platforms: https://briankeating.com/podcast #universe #podcast #briankeating #intotheimpossible #science #astronomy #cosmology #cosmicmicrowavebackground #intotheimpossible #briankeating #AnilAnanthaswamy Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 hr and 11 mins
  • Is the Universe Random or Deterministic, or Neither? (ft. Andrew Jaffe)

    Is the Universe Random or Deterministic, or Neither? (ft. Andrew Jaffe)
    Jan 12 2026
    Get My NEW Book: Focus Like a Nobel Prize Winner: https://www.amazon.com/dp/B0FN8DH6SX Andrew Jaffe Book: The Random Universe: https://www.amazon.com/Random-Universe-Models-Probability-Cosmos/dp/0300250509 Is the universe intrinsically random? In this conversation, we dive deep into why the universe may be fundamentally, intrinsically random. Whether inflation on life support, the truth behind the Hubble tension, and whether cosmology is approaching the event horizon, limits beyond which humans can never know. Today we're joined by one of the architects of modern cosmological inference, Professor Andrew Jaffee, author of a new book called The Random Universe that argues that every observation in science is shaped by the models we bring to it, biases and all. KEY TAKEAWAYS 00:00–01:13 — Science and life rely on building models. 01:13–03:35 — Models of people and reality are often wrong and revised. 04:04–06:01 — Observation depends on prior theories. 06:01–07:32 — Models can’t be escaped, only improved. 07:32–08:57 — No single scientific method exists. 08:57–11:25 — Science uses induction, not pure proof. 11:25–13:22 — Induction isn’t certain, only probabilistic. 13:22–15:36 — Induction works because nature is regular. 17:44–19:08 — Big Bang emerges from well-tested models. 19:08–21:15 — Current cosmology is stressed, not broken. 29:19–30:36 — Probability gives meaning to models. 39:45–41:11 — Randomness often reflects limited knowledge. 43:46–45:00 — Quantum physics is fundamentally probabilistic. 49:09–50:04 — Inflation awaits decisive observational tests. - Additional resources: Get My NEW Book: Focus Like a Nobel Prize Winner: https://www.amazon.com/dp/B0FN8DH6SX?ref_=pe_93986420_775043100 Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥 - Join this channel to get access to perks like monthly Office Hours: https://www.youtube.com/channel/UCmXH_moPhfkqCk6S3b9RWuw/join 📚 Get a copy of my books: Think Like a Nobel Prize Winner, with life changing interviews with 9 Nobel Prizewinners: https://a.co/d/03ezQFu My tell-all cosmic memoir Losing the Nobel Prize: http://amzn.to/2sa5UpA The first-ever audiobook from Galileo: Dialogue Concerning the Two Chief World Systems: Ptolemaic and Copernican https://a.co/d/iZPi9Un 📺 Watch my most popular videos:📺 Neil Turok https://www.youtube.com/watch?v=Dt5cFLN65fI Frank Wilczek https://youtu.be/3z8RqKMQHe0?sub_confirmation=1 Eric Weinstein vs. Stephen Wolfram https://www.youtube.com/watch?v=OI0AZ4Y4Ip4?sub_confirmation=1 Sir Roger Penrose: https://youtu.be/AMuqyAvX7Wo Sabine Hossenfelder: https://youtu.be/g00ilS6tBvs Avi Loeb: https://youtu.be/N9lUceHsLRw Follow me to ask questions of my guests: 🏄‍♂️ Twitter: https://twitter.com/DrBrianKeating 🔔 Subscribe https://www.youtube.com/DrBrianKeating?sub_confirmation=1 📝 Join my mailing list; just click here http://briankeating.com/list ✍️ Detailed Blog posts here: https://briankeating.com/blog 🎙️ Listen on audio-only platforms: https://briankeating.com/podcast #universe #podcast #briankeating #intotheimpossible #science #astronomy #cosmology #cosmicmicrowavebackground #intotheimpossible #briankeating #AndrewJaffe Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 hr and 12 mins
  • Max Tegmark vs. Eric Weinstein: AI, Aliens, Theories, & New Year’s Resolutions! (Repost from 2021)

    Max Tegmark vs. Eric Weinstein: AI, Aliens, Theories, & New Year’s Resolutions! (Repost from 2021)
    Jan 1 2026
    Win a $100 Amazon Gift Card! Help me help you get great guests on the Into the Impossible podcast and spread the message throughout the universe. Fill out this listener survey: https://forms.gle/EUKzyE2ZqXDYJ2F47 Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥 --- Enjoy this classic episode from the vault: Max Tegmark & Eric Weinstein, New Years Eve 2020! Brian Keating brings together two thought leaders at the edge of physics and philosophy: Max Tegmark, physicist, cosmologist, and pioneer at MIT, and Eric Weinstein, mathematician, economist, and creator of Geometric Unity. Timestamps: 00:00 "Ambitions in AI, Physics, News" 16:58 "Emergent Reality from Proto-Spacetime" 22:50 "Rethinking Unification in Physics" 36:09 "Value of Disagreeable Individualism" 45:32 "Optimism for Academia Careers" 01:04:08 "Dangers of Oversimplifying Physics" 01:07:34 "On Success, Science, and Wonder" 01:18:47 "Funding and Advancing Physics Research" 01:30:28 "Perspective on Science and Society" 01:43:13 "Three Types of Scientific Experiments" 01:52:05 "Collaboration and Discovery in Science" 02:02:20 "The Messiness of Scientific Truth" 02:13:08 "Simulation, AI, and Ethics" 02:20:55 "Limits of Technology in Cosmos" --- Join this channel to get access to perks like monthly Office Hours: https://www.youtube.com/channel/UCmXH_moPhfkqCk6S3b9RWuw/join 📚 Get my books: Think Like a Nobel Prize Winner, with productivity tips from 9 Nobel Prize winners: https://a.co/d/03ezQFu Focus Like a Nobel Prize Winner, with life-changing interviews with 9 Nobel Prizewinners: https://a.co/d/hi50U9U My tell-all cosmic memoir Losing the Nobel Prize: http://amzn.to/2sa5UpA The first-ever audiobook from Galileo: Dialogue Concerning the Two Chief World Systems: Ptolemaic and Copernican https://a.co/d/iZPi9Un Follow me to ask questions of my guests: 🏄‍♂️ Twitter: https://twitter.com/DrBrianKeating 🔔 Subscribe https://www.youtube.com/DrBrianKeating?sub_confirmation=1 📝 Join my mailing list; just click here http://briankeating.com/list ✍️ Detailed Blog posts here: https://briankeating.com/blog 🎙️ Listen on audio-only platforms: https://briankeating.com/podcast #universe #podcast #briankeating #intotheimpossible #science #astronomy #cosmology #cosmicmicrowavebackground #intotheimpossible #briankeating Learn more about your ad choices. Visit megaphone.fm/adchoices
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    2 hrs and 32 mins
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