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Let's Talk Alzheimer's

Let's Talk Alzheimer's

Written by: BrightFocus Foundation
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Welcome to Let’s Talk Alzheimer’s, your place to go for trusted insights from leading scientists and medical experts. Get the latest information on diagnosis, risk reduction, clinical trials, and the latest treatments. Presented by BrightFocus Foundation's Alzheimer's Disease Research program.Copyright 2026 Let's Talk Alzheimer's Hygiene & Healthy Living Physical Illness & Disease Science
Episodes
  • Alzheimer’s and Gum Disease: Exploring the Role of Oral Bacteria in Brain Health | Dr. Michael Detke

    Alzheimer’s and Gum Disease: Exploring the Role of Oral Bacteria in Brain Health | Dr. Michael Detke
    Jul 9 2026
    Could bacteria linked to gum disease play a role in Alzheimer’s disease? Emerging science suggests that P. gingivalis, a bacterium associated with gum disease, may contribute to inflammation and brain damage linked to Alzheimer’s disease. In this episode, Dr. Michael J. Detke of Lighthouse Pharma discusses the SPRING clinical trial and the investigational oral drug LHP588, which is being studied as a potential way to reduce bacteria-related brain damage. He also shares who may qualify for the study and what participation may involve for individuals with mild to moderate Alzheimer’s and their caregivers. To learn more, watch our full conversation with Dr. Detke, part of the Zoom In on Dementia and Alzheimer’s series. https://www.brightfocus.org/resource/the-spring-trial-targeting-gum-bacteria-in-alzheimers/ Support for Let’s Talk Alzheimer’s is provided by sponsors Lilly, Biogen, Eisai, and Genentech. Let’s Talk Alzheimer’s is presented by Alzheimer’s Disease Research, a BrightFocus Foundation program. We fund exceptional research across the globe to support the development of cutting-edge treatments, risk reduction strategies, and ultimately a cure for this mind-stealing disease. Visit brightfocus.org to learn more and get involved.
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    40 mins
  • Inside the Alzheimer’s Drug Pipeline: What New Clinical Trials Mean for the Future | Dr. Jeffrey Cummings

    Inside the Alzheimer’s Drug Pipeline: What New Clinical Trials Mean for the Future | Dr. Jeffrey Cummings
    Jun 25 2026
    Exciting advances in understanding Alzheimer’s biology, genetics, and biomarkers are driving new medicines, devices, and prevention strategies. In 2025 alone, 182 clinical trials evaluated 138 novel drugs for Alzheimer’s disease. In this episode, leading expert Dr. Jeffrey Cummings from the University of Nevada Las Vegas shares an insider’s look at the rapidly evolving Alzheimer’s treatment pipeline and what today’s clinical trials mean for the future. We also extend our gratitude to the clinical trial participants and families whose involvement makes this critical research possible
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    21 mins
  • Lifestyle & Brain Health: U.S. POINTER Study | Dr. Laura D. Baker

    Lifestyle & Brain Health: U.S. POINTER Study | Dr. Laura D. Baker
    Jun 11 2026

    Can everyday lifestyle choices really protect your memory? Dr. Laura Baker, professor at Wake Forest University School of Medicine, shares insights from the groundbreaking U.S. POINTER trial—the largest study of its kind exploring how lifestyle changes impact brain health. She breaks down how factors like exercise, nutrition, cognitive engagement, and social connection work together, and what practical steps you can take to reduce your risk of dementia.

    For a deeper dive into lifestyle and Alzheimer’s risk, watch our full conversation with Dr. Baker, part of the Zoom In on Dementia and Alzheimer’s series.

    Support for Let’s Talk Alzheimer’s is provided by sponsors Lilly, Biogen, Eisai, and Genentech.

    Let’s Talk Alzheimer’s is presented by Alzheimer’s Disease Research, a BrightFocus Foundation program. We fund exceptional research across the globe to support the development of cutting-edge treatments, risk reduction strategies, and ultimately a cure for this mind-stealing disease. Visit brightfocus.org to learn more and get involved.
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    33 mins
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