Multiple Chronic Conditions | Resource Center cover art

Multiple Chronic Conditions | Resource Center

Multiple Chronic Conditions | Resource Center

Written by: HealthCom Media
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Multiple Chronic Conditions (MCC) means that a person is living with two or more chronic conditions at the same time. Currently, 1 out of 3 adult Americans have MCCs and for persons 65 and older 4 out of 5 Medicare Beneficiaries and a growing number of children have MCCs. This is the largest patient population and users of healthcare resources accounting for 64% of all clinician visits, 70% of all inpatient stays, 83% of all prescriptions, 71% of all healthcare spending, and 93% of Medicare spending.

https://multiplechronicconditions.org/

Hygiene & Healthy Living
Episodes
  • Richard Knight and the APOL1 Action Alliance (AAA)
    Jun 15 2026

    The APOL1 gene is recognized as a kidney risk gene. APOL1-mediated kidney disease is a rapidly progressive form of proteinuria kidney disease. Although this gene is autosomal recessive the risk comes from the genotype of both parents. Compared with other chronic kidney disease patients, those of African ancestry with a confirmed APOL1 gene variant progress to dialysis 9 to 12 years earlier. APOL1-mediated kidney disease is often associated not only with proteinuria but also with a rapid decline in eGFR, earlier onset of kidney disease (including adolescence), and leads to a mean age of kidney failure in the U.S. of 45 years. Patients are often asymptomatic. Richard Knight, co-founder of the APOL-1 Alliance (https://apol1alliance.org/), provides a patient perspective on this condition.

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    30 mins
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