Episodes

  • Dr. Chris Palmer: Your Diet Could Be Causing Anxiety, Depression & Brain Fog (6 Simple Changes to Make Today)
    Jul 3 2026
    What if we've been thinking about mental illness all wrong? Harvard psychiatrist Dr. Chris Palmer argues that conditions like anxiety, depression, bipolar disorder, and schizophrenia may be rooted in metabolic dysfunction, not just genetics or trauma. Drawing on decades of clinical research, he explains which chemical additives may be harming our brains, why ketogenic diets are showing remarkable promise for severe mental illness, and why recovery is about far more than willpower. Chris also opens up to Jay about the deeply personal story of his mother that inspired him to pursue psychiatry, and why, despite the growing mental health crisis, he remains genuinely hopeful for the next generation. In this episode you'll learn: How to Recognize the Connection Between Diet & Mental Health How to Notice Warning Signs of Metabolic Dysfunction How to Support Loved Ones Through a Mental Health Crisis How to Become More Resilient with Self-Care How to Turn Personal Pain Into Purpose How to Use Fasting & Ketogenic Diets Safely How to Talk to Kids About Nutrition & Brain Health Healing rarely comes from one single fix. Instead it comes from understanding the whole person: body, brain, and everything we feed both. Sometimes the most radical form of self-love is simply asking what’s going into your body, and why? With Love and Gratitude, Jay Shetty JAY’S DAILY WISDOM DELIVERED STRAIGHT TO YOUR INBOX Join 900,000+ readers discovering how small daily shifts create big life change with my free newsletter. Subscribe https://news.jayshetty.me/subscribe Check out our Apple subscription to unlock bonus content of On Purpose! https://lnk.to/JayShettyPodcast What We Discuss: 00:00 Intro 00:22 The Chronic Disease Epidemic 01:54 The Link Between Mental Health and Diet 05:17 What Metabolism Really Means 07:57 The Shocking Chemicals Added to Food 09:55 Why Is The Food System In America So Harmful? 14:45 The Impact of Ultra Processed Foods on Mental Health 16:29 Why Your Brain Actually Needs Certain Foods 17:21 Brain Fog, Depression, Anxiety & Burnout 18:46 Building Mental Resilience 21:48 Self Care Will Improve Your Brain Functioning 23:57 The “Make America Healthy Again” Movement 25:25 The Next Era of Healthcare in America 27:45 A Healthy vs Unhealthy Metabolism 28:30 Warning Signs From Your Metabolism 29:13 93% of Americans Have Abnormal Biomarkers 30:00 6 Steps For Healing Your Metabolism 31:11 The Truth About Alcohol, Weed & Vaping 35:46 Exercise Doesn't Have to Be Extreme to be Effective 36:30 Stop Looking at Screens All Day! 37:10 Why No Single Diet Works for Everyone 38:45 The Power of Eating More Whole Foods 39:45 Do You Know What Your Body Needs? 40:20 What Are Nutrient Dense Foods? 41:17 Why Some People Are Metabolically Compromised 42:22 Dietary Intervention 44:00 The Ancient Power of Fasting 46:17 Why Bipolar Diagnoses Are Rising 50:08 When Medication Isn't Enough 51:24 How a Ketogenic Diet Can Impact Bipolar Disorder 53:06 The History of The Ketogenic Diet (It’s Not What You Think) 54:50 How The Ketogenic Diet Can Stop Seizures 56:20 The Power of Healing 57:47 The Unexpected Grief of Getting Better 59:05 A Life Dedicated to Psychiatry 1:04:15 Keeping a Healthy Dose of Skepticism 1:05:30 Rethinking New Treatments 1:06:55 Advice for Concerned Parents 1:07:31 What Are Epigenetics? 1:11:23 The Worst Chemicals For Brain Health 1:13:30 This Is An Ethics Issue… 1:14:09 Which Chemicals Cause Generational Anxiety? 1:18:20 Dr. Chris Palmer on Final Five Episode Resources: Read | Brain Energy Website | https://www.chrispalmermd.com/ YouTube | https://www.youtube.com/@ChrisPalmerMD Facebook | https://www.facebook.com/ChrisPalmerMD/ Instagram | https://www.instagram.com/chrispalmermd/ X | https://x.com/ChrisPalmerMD/See omnystudio.com/listener for privacy information.
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    1 hr and 22 mins
  • Lucy Kalanithi: What Loss Can Teach Us About Living (The Perspective Shift That Changes Everything)
    Jul 1 2026

    Ten years after the loss of her husband, neurosurgeon and bestselling author Paul Kalanithi, Dr. Lucy Kalanithi reflects on how grief continues to evolve rather than disappear. In this deeply moving conversation with Jay, she shares what it means to find purpose alongside pain, why the goal isn't to fix suffering but to make meaning from it, and how staying present through life's hardest moments can transform the way we love, heal, and truly live.

    In this episode you'll learn:

    How to Live Through Grief

    How to Support Someone Grieving

    How to Talk About Death

    How to Stay Present Through Pain

    How to Comfort Without Trying to Fix

    How to Honor Loved Ones

    How to Raise Resilient Children

    No matter what season of life you're in, remember that joy and sorrow can exist side by side. Healing isn't about leaving pain behind, it's about learning to carry it with greater compassion, presence, and hope.

    With Love and Gratitude,

    Jay Shetty

    JAY’S DAILY WISDOM DELIVERED STRAIGHT TO YOUR INBOX

    Join 900,000+ readers discovering how small daily shifts create big life change with my free newsletter. Subscribe https://news.jayshetty.me/subscribe

    Check out our Apple subscription to unlock bonus content of On Purpose! https://lnk.to/JayShettyPodcast

    What We Discuss:

    00:00 Intro

    01:20 Life After Loss

    03:22 A New Perspective on Death

    07:15 Does Time Really Heal?

    08:36 Does Everything Happen for a Reason?

    11:12 Helping Someone at the End of Their Life

    15:33 The Biggest Myth About Grief

    17:56 Preparing for Death

    23:08 Lessons From Facing Death

    30:28 You Are Stronger Than You Think

    35:33 Let Your Child Find Meaning On Their Own

    40:02 Choosing Family Despite Uncertainty

    43:48 A Different Way to Grieve

    47:38 Keeping a Loved One Alive After They’re Gone

    50:33 Can You Love Again?

    53:23 What Real Partnership Means

    57:19 Letting Go vs. Giving Up

    01:02:39 Sitting With the Dying

    01:05:58 Sharing Life-Changing News

    01:08:41 How to Live Well

    Episode Resources:

    LinkedIn | https://www.linkedin.com/in/lucy-kalanithi-baab214

    X | https://x.com/rocketgirlmd

    See omnystudio.com/listener for privacy information.

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    1 hr and 12 mins
  • Layla Taylor EXCLUSIVE: The Truth She's Finally Ready To Share
    Jun 29 2026

    In one of her most honest conversations yet, Layla Taylor reflects on the quiet journey of becoming herself. She opens up about coming out as bisexual, navigating faith, identity, single motherhood, and the weight of growing up feeling like she had to fit into everyone else's expectations. Rather than focusing on the hardships alone, this episode explores what happens when you stop living in survival mode and finally choose authenticity, self-worth, and the freedom to define your own life.

    In this episode you'll learn:

    How to Stop Living for Other People's Approval

    How to Finally Embrace Your Authentic Self

    How to Leave a Toxic Relationship Without Regret

    How to Find Yourself After Divorce and Heartbreak

    How to Be Comfortable Being Alone for the First Time

    How to Turn Your Hardest Experiences Into Strength

    The greatest freedom comes from embracing yourself with honesty, letting go of the expectations that no longer serve you, and trusting that growth often begins on the other side of fear. Your story doesn't have to be perfect to be meaningful, it just has to be yours.

    With Love and Gratitude,

    Jay Shetty

    JAY’S DAILY WISDOM DELIVERED STRAIGHT TO YOUR INBOX

    Join 900,000+ readers discovering how small daily shifts create big life change with my free newsletter. Subscribe https://news.jayshetty.me/subscribe

    Check out our Apple subscription to unlock bonus content of On Purpose! https://lnk.to/JayShettyPodcast

    What We Discuss:

    00:00 Intro

    00:48 Coming Out for the First Time

    02:45 Stop Living for Other People

    03:48 Choosing to Be Yourself

    06:33 Understanding Your Sexuality

    07:56 Why We Need to Talk About Sex

    10:08 Why I Became Mormon

    12:50 The Need to Fit In

    15:12 How My Kids Changed Me

    16:53 Becoming a Mom at 19

    18:15 Why I Chose Marriage

    19:53 Inside a Toxic Relationship

    21:04 Learning to Know Your Worth

    23:24 Starting Over as a Single Mom

    25:54 My Lowest Point

    27:31 Learning to Date Again

    29:05 Finding Yourself in Solitude

    30:32 The Conversation Women Need to Have

    33:08 Why Sex Education Matters

    36:26 Letting Go of Perfection

    36:59 Accepting Who You Are

    38:51 Facing Your Biggest Fear

    39:40 Dating Women for the First Time

    41:07 The Reality of Parenting

    43:00 Raising Mentally Healthy Kids

    44:16 Healing Low Self-Worth

    46:41 Using Your Platform for Good

    47:58 Opening Your Heart Again

    49:03 If You're Afraid to Come Out

    52:30 Layla on Final Five

    Episode Resources:

    Instagram | https://www.instagram.com/laylaleannetaylor

    TikTok | https://www.tiktok.com/@laylaleannetaylor

    See omnystudio.com/listener for privacy information.

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    57 mins
  • If You Can't Stop Thinking About Your Ex, Do This (The Path To Real Closure)
    Jun 26 2026

    Some endings hurt because they leave us with unanswered questions. After a breakup, it’s natural to search for reasons, replay memories, and hope for one final conversation that will make everything make sense. In this episode, Jay explores why closure is often misunderstood and how the answers we seek from someone else rarely bring the peace we’re hoping for. True healing begins when we stop waiting for another person to explain our pain and start turning inward instead.

    Jay shares a powerful perspective on heartbreak: closure is not something we receive, it’s something we create. Through acceptance, self-reflection, and intentional healing, we can transform loss into growth. Rather than centering our lives around what ended, we learn to rebuild around who we are becoming. The goal isn’t to erase the past, it’s to emerge from it with greater self-awareness, stronger boundaries, and a deeper trust in ourselves.

    In this episode you'll learn:

    How to Heal Through No Contact

    How to Rebuild Yourself After Heartbreak

    How to Separate Facts From Feelings

    How to Stop Romanticizing Your Ex

    How to Turn Heartbreak Into Growth

    How to Measure Healing the Right Way

    Heartbreak has a way of convincing us that healing is somewhere in the future, waiting behind the perfect explanation, apology, or final conversation. But growth often begins the moment we stop chasing what we cannot control and start caring for what we can.

    With Love and Gratitude,

    Jay Shetty

    JAY’S DAILY WISDOM DELIVERED STRAIGHT TO YOUR INBOX

    Join 900,000+ readers discovering how small daily shifts create big life change with my free newsletter. Subscribe here: https://news.jayshetty.me/subscribe

    Check out our Apple subscription to unlock bonus content of On Purpose! https://lnk.to/JayShettyPodcast

    What We Discuss:

    00:00 Intro

    01:46 Why More Answers Create More Questions

    05:52 The Power of No Contact After a Breakup

    08:44 Why Real Closure Comes From Within

    15:17 The Best Way to Find Closure

    18:45 The Biggest Mistake People Make After a Breakup

    20:55 It's Okay to Hold Contradictory Feelings

    23:56 Measure Healing in a New Way

    See omnystudio.com/listener for privacy information.

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    24 mins
  • John Mackey: Not Sure You're on the Right Path In Your Career? (Use THIS Framework When You Feel Lost About What's Next)
    Jun 24 2026

    For decades, we’ve been told that success and spirituality live in separate worlds. One is about achievement, the other about inner peace. In this conversation, John Mackey shares why he believes the two are deeply connected. Reflecting on the journey of building Whole Foods Market, he explores how purpose, intuition, gratitude, and conscious leadership shaped both his business and his life. From navigating near-failure and selling the company to Amazon, to redefining success beyond money and status, this episode is a powerful invitation to lead with more awareness, build with more heart, and create a life that feels as meaningful on the inside as it looks on the outside.

    In this episode you'll learn:

    How to Build a Business With Purpose

    How to Turn Setbacks Into Growth

    How to Find Joy in Your Work

    How to Turn Envy Into Learning

    How to Create a Culture People Never Want to Leave

    How to Make Difficult Decisions With Compassion

    How to Stay Connected to What Matters Most

    There will be setbacks, doubts, and moments when things don’t go according to plan, but those moments don’t define your journey. What matters is continuing to move forward with purpose, staying connected to what brings you joy, and remembering that success means little if it costs you who you are.

    John’s book, The Whole Story: Adventures in Love, Life, and Capitalism, talks about why Whole Foods isn’t just a business success story, it’s the story of a retail, cultural, and dietary revolution that has forever changed the industry and the way we eat. Grab a copy here: https://www.amazon.com/Whole-Story-Adventures-Love-Capitalism/dp/1637745125

    With Love and Gratitude,

    Jay Shetty

    JAY’S DAILY WISDOM DELIVERED STRAIGHT TO YOUR INBOX

    Join 900,000+ readers discovering how small daily shifts create big life change with my free newsletter. Subscribe https://news.jayshetty.me/subscribe

    Check out our Apple subscription to unlock bonus content of On Purpose! https://lnk.to/JayShettyPodcast

    What We Discuss:

    00:00 Intro

    02:37 Answering the Call to Adventure

    05:53 The Search for Meaning and Consciousness

    09:42 A Spiritual Awakening Through Psychedelics

    13:40 Exploring the Inner Universe

    17:45 Envy Steals Joy

    19:49 Understanding Ego Death

    24:54 The Power of Play and Creativity

    27:33 Follow What Brings You Joy

    29:36 Confronting Your Inner Critic

    33:45 Building a Business With Heart

    35:45 The Gift of Being Fully Present

    39:10 Responding to Life’s Greatest Challenges

    41:35 Turn Mistakes Into Growth

    44:24 The Rise of Conscious Leadership

    46:15 The Decision to Sell to Amazon

    53:34 A Year of Gratitude and Goodbyes

    55:23 Attracting Great People to Your Mission

    57:10 Letting People Go With Compassion

    59:45 John on Final Five

    Episode Resources:

    Website | https://johnpmackey.com/

    Facebook | https://www.facebook.com/iamjohnmackey

    Instagram | https://www.instagram.com/iamjohnmackey/

    LinkedIn | https://www.linkedin.com/in/iamjohnmackey

    X | https://x.com/iamjohnmackey

    Linktree | https://linktr.ee/iamjohnmackey

    See omnystudio.com/listener for privacy information.

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    1 hr and 2 mins
  • Dr. Jill Biden: The Hardest Moments No One Saw (The Untold Story of the White House Years)
    Jun 22 2026

    Today Jay sits down with former First Lady Dr. Jill Biden where she pulls back the curtain on an extraordinary journey of love, profound loss, and unrelenting public scrutiny. After first rejecting a young senator's marriage proposal five times, she and husband President Joe Biden ultimately built a family rooted in fierce loyalty and unwavering devotion. Jill shares what it takes to navigate life’s hardest moments - from the unimaginable grief of losing her son Beau to cancer, to her son Hunter's battle with addiction, to her husband's ongoing health struggles and heartbreaking political exit. Jill’s story highlights the radical power of staying present, and the impact of making a conscious decision to always choose joy no matter where you are in life.

    In this episode you'll learn:

    How to Move Forward After Major Life Changes

    How to Cultivate a Lasting Marriage

    How to Instill Confidence in Those Around You

    How to Advocate for Your Health

    How to Navigate Loving Someone Through Addiction

    How to Survive Unimaginable Grief

    As you navigate your own journey, remember to lead with compassion and be kind, because we never truly know the hidden struggles behind someone else's smile.

    In her new book, View from the East Wing: A Memoir, Jill shares her White House experiences for the first time, in her own words. You can order here: https://bit.ly/ViewFromTheEastWing

    With Love and Gratitude,

    Jay Shetty

    JAY’S DAILY WISDOM DELIVERED STRAIGHT TO YOUR INBOX

    Join 900,000+ readers discovering how small daily shifts create big life change with my free newsletter. Subscribe https://news.jayshetty.me/subscribe

    Check out our Apple subscription to unlock bonus content of On Purpose! https://lnk.to/JayShettyPodcast

    What We Discuss:

    00:00 Intro

    01:26 A New Life Trajectory

    06:39 Saying “No” Five Times

    08:03 Lessons in Independence

    09:56 Building Loving Relationships

    15:08 A Blessing in Disguise

    17:17 "My Husband Is Not Dying"

    19:26 Grieving Loved Ones

    21:18 A True Partnership

    23:01 Redefining Your Role

    23:53 The Weight of the World

    25:32 Practicing Radical Presence

    26:16 "We Won!"

    27:50 Life’s Greatest Gift

    31:52 Beyond the Classroom

    32:31 The Health Gap

    36:06 Panic in the Green Room

    38:04 "I Had No Choice"

    40:06 The Morning After

    42:20 Alternate Realities

    44:08 A Cruel Diagnosis

    45:31 Strength in the Storm

    46:12 An Unimaginable Loss

    48:55 Learning to Live With the Pain

    50:55 The Intervention

    52:42 Breaking the Stigma Around Addiction

    54:38 Jill on Final Five

    Episode Resources:

    Website | https://joebiden.com/

    Facebook | https://www.facebook.com/DrJillBiden/

    Instagram | https://www.instagram.com/drbiden

    X | https://x.com/DrBiden

    See omnystudio.com/listener for privacy information.

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    59 mins
  • Always “Too Tired” After Work? 5 Shifts to Optimize Your 5–9 and Finally Build the Life You Want
    Jun 19 2026

    We often tell ourselves that we’ll start pursuing our goals when we have more time, more energy, or more motivation. But the truth is that lasting change is usually built in the small pockets of time we already have. In this episode, Jay explores how the hours after work can directly shape our lives, revealing why so many people feel stuck despite having big dreams for themselves.

    Through practical insights and personal stories, Jay shares how to break free from autopilot routines, overcome decision fatigue, and create evenings that leave you feeling fulfilled rather than depleted. He reminds us that success is rarely the result of one dramatic decision, but of consistent choices that align with the person we want to become. The life you imagine for yourself may be closer than you think, it starts with how you spend today.

    In this episode, you'll learn:

    How to Reclaim Your Evenings

    How to Break the After-Work Autopilot

    How to Batch Tasks and Save Time

    How to Build Energy Instead of Draining It

    How to Turn Small Actions Into Big Results

    How to Use Your 5-to-9 to Change Your Life

    You don't need a perfect plan, endless motivation, or extra hours in the day to start moving your life forward. Real change is often built through small decisions made consistently, especially on the ordinary days when no one is watching.

    With Love and Gratitude,

    Jay Shetty

    JAY’S DAILY WISDOM DELIVERED STRAIGHT TO YOUR INBOX

    Join 900,000+ readers discovering how small daily shifts create big life change with my free newsletter. Subscribe here: https://news.jayshetty.me/subscribe

    Check out our Apple subscription to unlock bonus content of On Purpose! https://lnk.to/JayShettyPodcast

    What We Discuss:

    00:00 Intro

    01:19 Spending Your 5-9 Wrong

    04:12 Shift #1: Change Your First Habit After Work

    06:31 Shift #2: Batch Small Tasks to Avoid Getting Overwhelmed

    07:48 Shift #3: Stop Waiting to Feel Good Before Taking Action

    10:55 Shift #4: Give Yourself One Meaningful Goal Each Night

    12:48 Shift #5: Build Evenings That Help Regain Your Energy

    15:49 Make the Right Choices to Spend Your Evenings Right

    20:49 Positively Impact Your Future Years

    23:04 Work for the Things You Care About

    See omnystudio.com/listener for privacy information.

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    25 mins
  • Stop Waiting to “Figure It Out!” (Do THIS In The Next 48 Hours to FINALLY Take the First Step in Finding Your Purpose)
    Jun 19 2026

    Jay taps into the question so many people quietly carry: “Is this really what I’m meant to do?” With honesty and clarity, he challenges the myths we’ve been taught about purpose, that it’s a single calling, that passion comes first, or that clarity arrives before action. Instead, Jay reframes purpose as something you build through curiosity, experimentation, and small, consistent steps. He reminds us that most people aren’t lost, they’re avoiding what they already know because of what it might cost.

    Jay offers a practical framework for finding direction. He points to the things that come naturally, what deeply moves or frustrates you, the challenges you’ve lived through, and even who you envy as signals worth paying attention to. These aren’t random, they’re clues guiding you toward the work that’s truly aligned with you. The message is simple but powerful: stop waiting for certainty, start moving, and trust that clarity comes through action.

    In this episode you'll find:

    How to Find Your Purpose

    How to Turn Passion Into Purpose

    How to Start Before You’re Ready

    How to Overcome Fear of Failure

    How to Build Confidence Through Action

    How to Become More Yourself

    The quiet ideas you keep returning to, the things that light something up inside you, the dreams you keep pushing aside, they matter for a reason. Start where you are, with what you have, and trust that clarity often comes after action, not before it.

    With Love and Gratitude,

    Jay Shetty

    JAY’S DAILY WISDOM DELIVERED STRAIGHT TO YOUR INBOX

    Join 900,000+ readers discovering how small daily shifts create big life change with my free newsletter. Subscribe here: https://news.jayshetty.me/subscribe

    Check out our Apple subscription to unlock bonus content of On Purpose! https://lnk.to/JayShettyPodcast

    00:00 Intro

    01:21 The Biggest Lie About “Following Your Passion”

    02:20 The Myth of Having One True Calling

    03:25 Why You Won’t Feel Certain When You Find It

    04:06 Your Purpose Doesn’t Have to Be Your Job

    05:36 4 Real Places to Look for Your Purpose

    11:02 4 Hidden Obstacles That Keep You Stuck

    14:50 Stop Trying to “Find” Your Purpose — Start Testing It

    16:25 The 1% Rule That Changes Your Direction

    17:44 Stop Talking About It, Start Doing the Work

    18:43 Your Environment Shapes Your Future

    19:39 Discomfort Means You’re on the Right Path

    20:27 The One Action to Take in the Next 48 Hours

    22:26 The 3 Paths That Lead You to Purpose

    See omnystudio.com/listener for privacy information.

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    25 mins