Opioidology Part 3: Opioid-Philia vs Opioid-Phobia The often-blurred lines of pain, addiction, and substance use need a deeper dive into the extremes of opioid-philia and opioid-phobia (building upon Opioidology Part 1: Our Opioid Story). Join Mark “Pain Guy” Garofoli and our two guests James Hackworth and Jim Potenziano to take that deeper dive based on their recent collaboration in the Frontiers in Pain Research article “The Burden of Acute Pain in the U.S. in the Wake of the Opioid Crisis”. • Frontiers in Pain Research Article: https://www.frontiersin.org/journals/pain-research/articles/10.3389/fpain.2025.1642035/full • Article Key Takeaways • Rising Pain Prevalence • Balancing Act—Opioid Utilization vs. Undertreatment • Provider Reluctance to use opioids • Patient Reluctance • Massive Economic Impact • Call for Innovation & Policy Reform • Opioid Story charts: www.painguy.us

In this episode of the Rated Rx Podcast, pharmacists break down the biggest healthcare news of 2025 and what it actually means for patients and clinicians 👀💊. You hear real pharmacist perspectives on artificial intelligence in healthcare, new federal plans to regulate AI, and why clinical judgment, patient trust, and human decision making still matter more than algorithms 🤖➡️🧠. The conversation also dives into major vaccine policy changes, including updates to newborn hepatitis B vaccination recommendations and why shifts like this raise real concerns for public health 🧬🩺. The crew explains what these changes mean in practice, how misinformation spreads fast, and why prevention still saves lives. Later, the episode tackles the explosion of GLP 1 weight loss medications like semaglutide and tirzepatide. You hear honest discussion about access, cost, compounding risks, and why obesity needs to be treated as a chronic disease instead of a personal failure ⚖️📈. This episode blends news, clinical insight, and real world experience to unpack where healthcare is heading next. This podcast is intended for entertainment and informational purposes only. Listen and Follow Rated Rx 🎙️ Apple Podcasts https://podcasts.apple.com/us/podcast/the-rated-rx-podcast/id1804181016 Spotify https://open.spotify.com/show/7KATtG1c3HwwYpVMtRuNub Facebook https://www.facebook.com/profile.php?id=61574813907982 Instagram https://www.instagram.com/ratedrxpodcast/ TikTok https://www.tiktok.com/@ratedrxpodcast

In this edition of Essential, we’ve got concerns about the FDA’s revolving door, some issues with a new California law that might affects the whole country, and a new accreditation that might save a lot of headache. Then we take a deep dive into the once and future world of compounded peptides — where they are, and where they might be going … and why. Links FDA’s revolving door: https://archive.ph/oxBXP Join APC today: https://a4pc.org/membership Coalition for Compounding Excellence (CCE) accreditation: https://414uue.share-na2.hsforms.com/2n_hRAnRSQ4O8VteGTesF0Q?_hsenc=p2ANqtz-9rfyq3GuFFZw6omRa96tq_es549FWmjiw-sP5NU3LKrsL1eump-l18h7xVrvy8G_V1Pi4UFkfhARMnPCLIx7TBOwPClQ&_hsmi=394109070 Pharma Source Direct: https://www.linkedin.com/company/pharma-source-direct/

I was truly inspired by today’s guest and her courage to follow her inner guidance, which served her not only on her personal journey but also led her to found a beautiful company with a sacred mission. Osi Mizrahi is the founder and visionary behind OSI Oils—a wellness brand rooted in slow beauty, Ayurvedic ritual, and the art of coming home to oneself. Born on a farm in Israel, Osi’s connection to the natural world began early, shaping her journey as a medical intuitive, Ayurvedic artisan, and guide in the healing arts. With over 30 years of experience in yoga, Ayurveda, Reiki, Kundalini, and Theta Healing, Osi blends ancient wisdom with feminine embodiment. Her work is inspired by Kabbalah, breathwork, and intuitive practices that support deep transformation. Osi believes in slow beauty and slow aging—practices that honor the body’s rhythms and nourish vitality over time. Oils, for her, are more than skincare—they are vessels of self-love, sensuality, and spiritual healing. Each OSI Oils formula is handcrafted in small batches using traditional Ayurvedic methods, turning everyday routines into sacred rituals. Whether soothing the nervous system with her belly oil or igniting life-force energy with Radiance Hair Oil, her products are designed to restore from the inside out. Osi’s upcoming book shares her own journey through heartbreak, healing, and the power of ancient rituals. Through her storytelling, mentorship, and botanical creations, she helps women around the world reconnect to their spark—and live with more pleasure, purpose, and presence. Connect with Osi via: Email: osi@osioils.com Website: Osi Oils IG: @osioils YT: @OsiMizrahi Linked In: Osi Mizrahi Use My Special Promo Code RAWFORK20 for 20% off orders on osioils.com Visit https://marinabuksov.com for more holistic content. Music from https://www.purple-planet.com. Disclaimer: Statements herein have not been evaluated by the Food and Drug Administration. Products listed are not intended to diagnose, treat, cure, or prevent any diseases.

In this episode we hear from:

Jessica Daley

Josh Hart - OPTU Consulting

Matt Gilbert - RxSafe

Mike Salazzo - Capital Drug

Paul Shelton - LTC@Home