Rodrigo Brandão joins co-hosts Kate d'Adamo and Daniel W.K. Lee to explore the evolving role of media, activism, and art in driving social change. Rodrigo recounts his path from film student to communications leader, highlighting the value of storytelling and community in organizing. The episode examines the struggle for independent journalism, the strategic use of social media, and the need for inclusive coalitions. Listeners gain insight into Rodrigo’s philosophy of joyful, art-infused activism and the lessons learned from both Brazilian and American movements.

The sugar cookies get extra sprinkles with this December Reply All episode recorded LIVE at the end of 2025 featuring Mattie Bynum, Kenyon Farrow, Daniel W.K. Lee, and Shane Lukas as the team concludes with a "year-in-review" analysis of the most overlooked and over-focused LGBTQ+ stories of 2025, including the impact of government funding cuts on HIV/AIDS programs and the often-ignored role of class within the queer community. Despite the year's hardships, the hosts share their personal highlights—from literary awards to returning to the acting stage—and set their intentions for continued advocacy and community building in 2026.

Shawn Aaron takes the guest seat in conversation with co-hosts Mattie Bynum and Shane Lukas to discuss the origins of his organization, Dem Bois Inc., which advocates for access to gender-affirming care and surgeries for trans men of color. He shares deeply personal accounts of past homelessness and family struggles, emphasizing his core philosophy that "visibility equals possibility". By being open about his own story, Shawn aims to be a beacon for others who may currently be in difficult circumstances, showing them that a different future is possible.