Systemic Drug Effects on Vision
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Hi, I am Dr Thomas Whitelaw and welcome back ‘Basic Sciences in Ophthalmology ‘ in Episode 61, we're looking at an important connection between general medicine, pharmacology and ophthalmology: the effects of systemic and locally administered drugs on vision.
A medicine prescribed to treat disease elsewhere in the body can sometimes have significant ocular consequences.
Some drugs damage the retina.
Some alter aqueous humour outflow and increase intraocular pressure.
And others interfere with the metabolism of the optic nerve.
For the ophthalmology trainee, three particularly important examples are chloroquine and hydroxychloroquine, corticosteroids, and ethambutol.
These drugs affect three different parts of the visual system and illustrate three very different mechanisms of toxicity.
Today's episode is therefore divided into three sections:
First: antimalarials and retinopathy.
Second: steroids and glaucoma.
And third: ethambutol and optic neuropathy.
Everything in this episode is based exclusively on the ophthalmology texts supplied for this podcast project.