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Vitreoretinal Interface Dynamics

Vitreoretinal Interface Dynamics

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Hi I am Dr Thomas Whitelaw, welcome back to Basic Sciences in Ophthalmology.

In Episode 63, we're exploring one of the most mechanically fascinating regions of the eye: the vitreoretinal interface.

The vitreous is often thought of simply as the transparent gel filling the posterior segment. But the relationship between the posterior vitreous cortex and the retinal surface is dynamic. It changes with age, and the way in which the vitreous separates—or fails to separate—from the retina can have major consequences for vision.

At the macula, persistent attachment can generate vitreomacular traction.

Cellular proliferation on the retinal surface can produce an epiretinal membrane.

And with ageing, liquefaction and collapse of the vitreous can eventually produce a posterior vitreous detachment, or PVD.

These are not completely separate processes. The uploaded Yanoff text describes vitreomacular traction, epiretinal membrane and several other macular disorders as part of a spectrum related to variations in anomalous posterior vitreous detachment.

So today we'll examine three interconnected processes:

First: vitreomacular traction.

Second: epiretinal membranes.

And third: posterior vitreous detachment.

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