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Are you taking calcium or vitamin D? This book could save your life! Learn the secret to avoiding osteoporosis and heart disease. Millions of people take calcium and Vitamin D supplements thinking they're helping their bones. The truth is, without the addition of Vitamin K2, such a health regimen could prove dangerous. Without Vitamin K2, the body cannot direct calcium to the bones where it's needed; instead, the calcium resides in soft tissue, like the arteries, leading to a combination of osteoporosis and atherosclerosis, or the dreaded "calcium paradox".

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Cardiomyocyte calcium handling is a major determinant of excitation-contraction coupling. Alterations in one or more calcium-handling proteins may induce arrhythmias through the formation of ectopic activity, direct and indirect ion-channel regulation, and structural remodeling. Due to the complex and tight interactions between calcium and other molecules within a cardiomyocyte, it remains experimentally challenging to study the exact contributions of calcium-handling abnormalities to arrhythmogenesis. Multiscale computational studies performed in close collaboration with laboratory ...