American Dementia

For decades, researchers have chased a pharmaceutical cure for memory loss. But despite the fact that no disease-modifying biotech treatments have emerged, new research suggests that dementia rates have actually declined in the United States and Western Europe over the last decade. Why is this happening? And what does it mean for brain health in the future?

Brain diseases such as Alzheimer’s and Parkinson’s affect an estimated one in six Americans and are increasing in incidence as the population ages. In this audiobook, we examine these and other conditions involving the damage and loss of neurons, including other forms of dementia, amyotrophic lateral sclerosis (ALS), chronic traumatic encephalopathy (CTE), and multiple sclerosis (MS).

Until recently, one idea has dominated research in treating Alzheimer’s disease: the amyloid hypothesis. Those therapies have repeatedly fallen short, and in this audiobook we take a look at where that hypothesis stands today. We examine recent research into the spectrum of disease causes, including inflammation and immune dysfunction; cutting-edge treatments, including deep-brain stimulation and magnetic resonance - guided focused ultrasound; as well as lifestyle interventions that can help protect from disease.