Avery Weston is doing fine. Sure, she’s not doing as fine as her ex - award-winning actress and current television it girl Elise Hayes - but Avery enjoys her work as a federal air marshal and also enjoys almost being over Elise walking out on their relationship 15 months ago. Then Elise is seated next to her on a flight, and the emotional progress Avery thought she’d made is reset in an instant.

Librarian Syd Murphy flees the carnage of a failed marriage by accepting an 18-month position in Jericho - a small town in the Appalachian Mountains of Virginia. Her plans to hide out and heal her wounds fall by the wayside as she gets drawn into the daily lives of the quirky locals. She becomes fast friends with Maddie Stevenson, the enigmatic physician who has returned to the backcountry community to take over her late father's medical practice.

Emma Cole has left behind her family and an ex-fiance to move to Chicago and start over. When a mix-up lands her a job at a high-profile law firm, Emma is determined to meet this new challenge head-on. What she didn't count on was working for a woman like Lillian White, and it doesn't take long for Emma to realize that she might be in over her head in more ways than one. 

After nearly a decade as a professional drummer, Diana Petrell leaves her rock-star life behind to continue her residency in emergency medicine. She's determined not to let anything stop her - not even falling in love with her aloof mentor, Dr. Emily Barnes. Emily has only ever focused on her career as a senior attending in the emergency department, and she isn't happy about having to babysit a resident with a 10-year gap in her resume, no matter how intriguing she is. But every time they work together, it's not just their patients' heartbeat that gets a little irregular.

Jana Fleischer loves her life - wonderful family, best sister in the world, awesome soon to be sister-in-law, fabulous job, and a never-ending stream of men to chew through and spit out. So what if everyone says she’s too picky and she’s never had a real relationship? When a chance meeting with Brooke Donnelly leaves Jana literally and figuratively off-balance, it doesn’t take long for her initial annoyance to turn into the first sparks of friendship.