In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, to explore recent examples of diagnostic innovations that are improving patient care. Dr. Pritt also welcomes Matthew Schultz, Ph.D., a clinical biomedical geneticist at Mayo Clinic, to discuss how a novel test is delivering answers for patients with a recently identified peripheral neuropathy.

• Transplant testing innovations (00:57): Discover how advances in clinical diagnostics are improving transplant outcomes at Mayo Clinic.
• Advances reshaping rheumatoid arthritis diagnostics (06:06): Learn how early-stage research and emerging tools are reshaping care for patients with rheumatoid arthritis.
• New test for peripheral neuropathy (08:18): A novel test created to support care for patients with a recently identified condition now supporting research to advance care.

Note: Information in this post was accurate at the time of its posting.

Resources

• Rewriting the future of rheumatoid arthritis: How early detection is transforming prevention
• Cultivating a comprehensive test menu for organ transplant patients
• Screening test for sorbitol dehydrogenase deficiency-related neuropathy (SORD)
• Innovative SORD test provides clarity for two young patients: Justin Fugelsang and Zach Pedowitz

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, to discuss recent industry news and how collaborations are helping drive transformation in clinical diagnostics. Together, they explore:

• Protecting Access to Medicare Act (PAMA) delay (01:09): Dr. Morice shares what the latest delay of PAMA means for laboratories.
• FDA guidance on wearables (02:23): Learn about recent FDA guidance that allows more non‑invasive wearables to be classified as wellness devices.
• Collaboration as a driver of innovation (06:20): Discover why collaboration is critical to advancement in clinical diagnostics.

Note: Information in this post was accurate at the time of its posting.

Resources

• Groundbreaking collaborations
• Mary Jo Williamson offers four steps to maximize collaboration benefits
• Dr. Bill Morice shares how a platform for collaboration transforms diagnostics
• “Answers From the Lab” podcast: “Forging Collaborations That Deliver Better Outcomes”

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, to discuss Protecting Access to Medicare Act (PAMA) reform and celebrate an exciting milestone for Dr. Pritt’s “Creepy Dreadful Wonderful Parasites” blog. Later in the episode, Dr. Pritt welcomes Angie Reese-Davis, Mayo Clinic Laboratories’ director of operations, to explore how proactive monitoring, shipping workflows, teamwork, and ongoing process improvements all contribute to a resilient lab logistics system.

• PAMA reform update (00:34): Get the latest on PAMA delays and the new Reforming and Enhancing Sustainable Updates to Laboratory Testing Services (RESULTS) Act.
• Creepy Dreadful Wonderful Parasites (04:24): Go behind the scenes of the 800 parasite cases Dr. Pritt has featured on her long-running blog.
• Logistics at Mayo Clinic Laboratories (08:09): Learn how the team manages and tracks the 40,000 samples that arrive each day.
• Process improvement and resiliency (12:49): Discover how the logistics team continues to innovate and evolve to support clients more efficiently and effectively.

Note: Information in this post was accurate at the time of its posting.

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, to discuss 2026 trends. Together, they explore:

• JP Morgan Healthcare Conference (00:34): Dr. Morice shares his top observations and takeaways after attending this year’s conference.
• Artificial intelligence (06:02): Anticipated benefits and risks of AI developments predicted in 2026.
• Reimbursement and regulation (13:43): Why reimbursement and regulation continue to be areas of significant interest in clinical diagnostics.

Note: Information in this post was accurate at the time of its posting.

Resources

• Transforming laboratory medicine through AI: From promise to practice
• "Answers From the Lab" podcast: Breakthroughs and Trends That Defined Lab Medicine in 2025
• "Answers From the Lab" podcast: PAMA Update and Accelerating Research and Development With BioPharma Diagnostics

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, to discuss direct-to-consumer testing. Then, Dr. Pritt welcomes Matthew Binnicker, Ph.D., a microbiologist and virologist and chief scientific officer of Mayo Clinic Laboratories, for a conversation about accelerating innovation without compromising quality or safety.

• Direct-to-consumer testing (00:38): Explore the rise of direct-to-consumer testing and the challenges that accompany it.
• Evolving expectations for innovation (05:38): Understand why patient and clinician expectations are rising and how that is reshaping diagnostics.
• Safeguarding advances (07:23): Learn the foundational principles that protect quality and safety amid rapid innovation.
• Strategies for accelerating innovation (10:33): Discover practical ways to responsibly deliver novel solutions more quickly.

Note: Information in this post was accurate at the time of its posting.

Resources

• Five ways to move faster without compromising trust in diagnostics
• "Answers From the Lab” podcast: Breakthroughs and Trends That Defined Lab Medicine in 2025
• 360Dx: 2025 highlights and takeaways for the clinical lab industry

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, welcomes William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, to explore recent news updates and key advancements shaping the industry in 2025.

• Staying healthy during the holidays (00:18): Discover how to protect yourself and others as a new influenza strain, holiday gatherings, and increased travel raise the risk of spreading viruses.
• 2025 breakthroughs and trends (04:31): Learn more about the technologies, regulations, and innovation influencing the future of clinical diagnostics.

Note: Information in this post was accurate at the time of its posting.

Resources

• "Answers From the Lab” podcast: Innovations Set to Shape the Industry in 2025
• Dr. Morice shares trends and predictions for 2025
• Mayo Clinic Minute: How to prepare for the influenza season
• Mayo Clinic Minute: Wash your hands for better health
• Vaccines and viruses: Protecting health across generations

Published Dec. 4, 2025

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, to discuss Protecting Access to Medicare Act (PAMA) reform and the first reported death from alpha-gal syndrome. Later, Dr. Pritt welcomes Chris Garcia, M.D., Mayo Clinic Laboratories’ chief digital innovation officer and medical director of BioPharma Diagnostics, to explore how biopharma diagnostics advance research and development.

• PAMA reform update (00:33): Get the latest on where reform to PAMA stands following the federal government’s reopening.
• Alpha-gal syndrome case (03:22): Learn about the first known death from alpha-gal syndrome and diagnostic testing for this tick-bite-triggered red meat allergy.
• Biopharma’s role in research and development (07:52): Discover how biopharma diagnostics fuel innovation and how digital tools are expanding its future impact.

Note: Information in this post was accurate at the time of its posting.

Resources

• BioPharma Diagnostics: Connecting pharma and biotech
• Tick-borne disease: An expanding geographic threat

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, to discuss recent news about Protecting Access to Medicare Act (PAMA) reform. Then, Dr. Pritt welcomes Trish Simner, Ph.D., a clinical microbiologist at Mayo Clinic, for an in-depth conversation about metagenomics.

• PAMA reform update and new RESULTS Act (00:30): Hear about options under consideration for PAMA reform, including the Reforming and Enhancing Sustainable Updates to Laboratory Testing Services (RESULTS) Act.
• When cerebrospinal fluid (CSF) metagenomics benefit patient care (06:04): Explore how CSF metagenomics work and when it is appropriate to use this advanced diagnostic tool in clinical practice.
• Advancement and innovation in metagenomics (18:15): Discover how recent and upcoming innovation is expanding metagenomic testing capabilities.

Note: Information in this post was accurate at the time of its posting.

Resources

• Answers From the Lab podcast: Developments for LDT Regulation and Laboratory Reimbursement: Bill Morice, M.D., Ph.D.
• Metagenomics: Identifying elusive pathogenic microorganisms