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Biohacking Beauty: The Anti-Aging Skincare Podcast

Biohacking Beauty: The Anti-Aging Skincare Podcast

Written by: Young Goose
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Welcome to Biohacking Beauty, the definitive exploration of skin health through the lens of longevity medicine and cellular biology. Hosted by the founders of Young Goose, Amitay Eshel and Anastasia Khodzhaeva, this podcast moves beyond "single-molecule" trends to uncover the multi-mechanism protocols required to optimize the body’s largest organ. We bridge the gap between systemic longevity research and topical application. By hosting world-renowned experts in mitochondrial health, epigenetic signaling, and regenerative medicine, we translate complex research into actionable strategies for biological recalibration. From the 12 Hallmarks of Aging to the latest in bio-harmonizing lifestyle shifts, Biohacking Beauty provides the molecular tools and insights needed to align your skin’s appearance with your body’s peak biological potential.Copyright 2026 Young Goose Alternative & Complementary Medicine Art Hygiene & Healthy Living
Episodes
  • 260. Dr. Jennifer Berman: Peptides, Hormones, and the Anti-Aging Protocol Most Women Start Too Late
    Jul 1 2026

    We have been getting the same question in our DMs for months now. Peptides are everywhere. Everyone is talking about them. But what actually has evidence behind it, what is hype, and where do hormones fit into all of this? So we went and found someone who has been living this conversation for 35 years, not just talking about it.

    Dr. Jennifer Berman is a urologist, New York Times bestselling author, and one of the leading voices in female sexual and menopausal health. She pioneered the field at UCLA, runs the Berman Women's Wellness Center in Beverly Hills, and has been her own first patient through every transition she now treats. She is the kind of doctor who was doing things a decade before they became mainstream and has the clinical receipts to back all of it up.

    In this episode we get into why peptides are the missing piece of the menopause puzzle, what hormones are really doing to your skin from the inside out, and how treatments that were written off as fringe became the new gold standard for longevity.

    What's Discussed:

    (01:42) Why peptide production declines with age and what that actually means for how women look and feel in perimenopause.

    (04:04) The regulatory reality around peptides right now and why medical grade from a 503B pharmacy is the only route worth taking.

    (06:07) The specific peptides with the strongest evidence for skin, muscle, fat loss, recovery, and cognitive function.

    (13:12) Why your mid to late 30s is already perimenopausal by definition and why that changes when you start.

    (15:02) C-Link, C-Max, and PE22-28 for mood, neuroplasticity, and cognitive protection and why Dr. Berman stacks them together.

    (39:17) The exact point where topical skincare stops being enough and what hormone imbalance is doing to skin that no cream can fix.

    (53:08) Why cycling your peptides matters, what receptor attenuation actually is, and why the protocol on your feed is not a clinical protocol.

    By the end of this episode you will know which peptides have actual evidence behind them, where topical skincare stops working without hormonal support, and what an inside-out longevity protocol looks like from a doctor who has lived every transition she treats.

    Resources Mentioned:

    Age-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/

    FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/

    Find more from Young Goose:

    Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

    Instagram: @young_goose_skincare

    Find more from Dr. Jennifer Berman:

    Website: bermansexualhealth.com/

    Instagram: @jenbermanmd

    Show More Show Less
    1 hr and 5 mins
  • 259. Dr. Dan Pardi: How Creatine Supports Brain Function, Skin Health, and DNA Repair
    Jun 24 2026

    Creatine has been boxed in as a gym-bro supplement for decades, but the latest research shows it's doing far more than building muscle. It buffers brain energy under sleep deprivation, supporting bone density and mood stability through perimenopause, and freeing up methyl groups for detoxification and DNA repair.

    We dive deeper into this in the Biohacking Beauty Podcast with Dr. Dan Pardi. We also chat about why the bloating myth is backwards, how creatine and NAD work synergistically to support mitochondrial energy, and what topical creatine could mean for the future of skincare.

    Dr. Dan Pardi is a researcher whose first study in the 1990s focused on creatine, and he has spent three decades following the science as it expanded from sports performance into brain health, healthspan, and women's physiology. He is the Chief Health Officer at Qualia Life Sciences, where the team has earned recognition from the Nutrition Business Journal for science and innovation.

    His work focuses on translating peer-reviewed research into formulations that support cellular energy, methylation, and longevity.

    Let's dive in.

    Use code YOUNGGOOSE at https://www.qualialife.com/ for a special discount.

    What's Discussed:

    (4:32) Why creatine went from a niche Olympic edge to a billion-dollar category after the 1992 Games.

    (11:18) The sloping-surface analogy that explains why 5 grams saturates muscle but barely touches the brain.

    (15:47) How creatine buffers cognitive performance under sleep deprivation, with no decrement at baseline.

    (22:05) Why the bloating myth is backwards and what intracellular hydration actually feels like.

    (28:40) Topical creatine, the dermal layer, and why molecule size matters for skin delivery.

    (36:22) The decade of creatine in women: bone density, mood, and energy fluctuations through menopause.

    (42:15) Where the hair loss rumor really came from, and why creatine took the blame.

    (51:08) Why 40% to 70% of your body's methylation goes to making creatine, and what that means for NAD stacking.

    Find more from Young Goose:

    Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

    Instagram: @young_goose_skincare

    Find more from Dr. Dan Pardi:

    Instagram: @drdanpardi

    Substack: @drdanpardi

    Find more from Qualia:

    Website: qualialife.com

    Instagram: @qualialife

    Qualia Creatine: qualialife.com/shop/qualia-creatine

    Show More Show Less
    52 mins
  • 258. SPF Is Not Enough: The Cellular Repair Protocol Your Skin Needs This Summer
    Jun 17 2026

    When summer skin starts looking dull, congested, tired, or slower to recover, it is easy to blame the obvious things: heat, sweat, sunscreen, long days outside, or the wrong moisturizer. So the conversation usually stays on the surface. Use SPF. Cleanse better. Switch to lighter products. Add antioxidants. But before we treat summer skin like another product problem, there is a deeper question worth asking: what is the sun doing to the cell before you ever see the damage in the mirror?

    In this episode of Biohacking Beauty, I want to take the sun conversation past burns, wrinkles, and dark spots. I’m walking through what UV exposure does to the systems your skin depends on to keep up with summer: cellular energy, NAD, mitochondrial function, and DNA repair. Because the skin does not only need protection from the sun. It also needs enough repair capacity to deal with the damage that gets through.

    Young Goose's Skin Under the Sun campaign is active from June 15 through June 28 at younggoose.com

    What’s Discussed:

    (01:50) The light-activated repair tool humans lost.

    (06:10) Why NAD matters for skin energy and repair.

    (10:15) How UV exposure increases oxidative stress and disrupts NAD supply.

    (16:44) What UV-induced DNA lesions are and why CPDs matter.

    (22:21) Why L.A.D.R. serum was built around light-activated repair-inspired science.

    (31:52) Why the sun is one of the biggest controllable inputs into biological skin aging.

    (35:43) The five protocol-level moves for supporting skin through summer.

    Listen to this episode of Biohacking Beauty to understand what UV is doing under the surface and how to build a smarter summer protocol around protection, energy, and repair.

    Resources Mentioned:

    Age-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/

    FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/

    Find more from Young Goose:

    Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

    Instagram: @young_goose_skincare

    Show More Show Less
    39 mins
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