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Lifespan with Dr. David Sinclair

Lifespan with Dr. David Sinclair

Written by: Lifespan Communications LLC
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Lifespan with Dr. David Sinclair is a health and science show on how to live longer and stay healthier - grounded in the latest longevity research. A Professor of Genetics for over 25 years at Harvard Medical School and a leader in the field of longevity research, Dr. Sinclair breaks down the latest studies into clear, applicable insights so that you can perform at your best and live your longest, healthiest life. Season 1 ranked #1 in Health & Wellness podcasts. Season 2 is now live, starting with two Rewind episodes, followed by new episodes detailing the latest breakthroughs in aging science. Become a Lifespan member at lifespan.com. New episodes every two weeks.Lifespan Communications LLC Hygiene & Healthy Living
Episodes
  • The Most Surprising Longevity Discoveries | Lifespan with Dr. David Sinclair Rewind

    The Most Surprising Longevity Discoveries | Lifespan with Dr. David Sinclair Rewind
    May 21 2026
    What are the most important things you can do today to live longer and stay healthier while doing it? In this final Lifespan Rewind episode, Dr. David Sinclair, A.O., Ph.D., a Professor of Genetics for over 25 years at Harvard Medical School and a leader in the field of longevity research, revisits the most surprising insights from his #1-ranked Season 1 series, combining updated commentary with key moments from across all eight episodes. The result is a thought-provoking, focused, practical guide to the science of longevity – grounded in evidence and designed for real-world application. Whether you're new to longevity science or looking to refine your approach, this episode brings together the most important principles in one place so you can better understand not just what to do, but why it matters. At Lifespan, our mission is to help you and your loved ones live longer, healthier lives while supporting medical research aimed at breakthroughs to extend all our lives. Join us at: https://lifespan.com. We’re building the world’s largest longevity community who will grow, learn, and live longer together. Subscribe here for new Lifespan show episodes every two weeks. __________________________________________ Partners of the Lifespan show help us keep this program freely available as an educational resource while also supporting medical research. We only collaborate with partners whose products are grounded in strong science – and products our team has personally used for many years. Our selected partners make it convenient for the Lifespan audience to access the tools and technologies featured in this episode – from exogenous fuel for neurons (Ketone-IQ), to wearables that track recovery, strain, and sleep (WHOOP), to smart devices that measure key health metrics such as visceral fat content and muscle gains (Withings). If you’d like to learn more or try these tools: ○ Ketone-IQ: Get 30% off your first monthly order at https://ketone.com/lifespan with code LIFESPAN ○. WHOOP: Get a free WHOOP band plus one month free at https://join.whoop.com/LIFESPAN with code LIFESPAN ○. Withings: Explore their smart health devices at https://withings.com/lifespan using code LIFESPAN __________________________________________ Legal & Medical Disclaimers The Lifespan show and all related content are provided for informational and educational purposes only and are not intended as medical advice, diagnosis, or treatment. Nothing presented should be interpreted as a recommendation to diagnose, treat, cure, or prevent any disease or medical condition. This content is not a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. You should always consult with a licensed physician or other qualified healthcare professional before making decisions about your health, including starting, stopping, or modifying any treatment, supplement, diet, or exercise program. The information shared reflects the views and opinions of the host and guests and is based on the scientific literature, their experience and expertise, and general wellness principles. Listening to or engaging with Lifespan content does not establish a doctor–patient or clinical relationship. Health and longevity outcomes can vary significantly between individuals. Any references to studies, interventions, products, or protocols are not guarantees of specific results, and individual responses may differ. From time to time, Lifespan may discuss or partner with third-party products or services. These references are provided for informational purposes only and should not be considered medical recommendations or endorsements of efficacy for any individual. Lifespan Foundation is an independent 501(c)(3) non-profit organization whose mission is to support medical research. The views expressed by Dr. David Sinclair, A.O., Ph.D., are his own and do not represent those of Harvard University, Harvard Medical School, or any affiliated institutions.
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    1 hr and 16 mins
  • Season 2 Official Trailer: Lifespan with Dr. David Sinclair

    Season 2 Official Trailer: Lifespan with Dr. David Sinclair
    May 18 2026
    What if aging is more reversible than we once thought? Season 2 of Lifespan with Dr. David Sinclair, A.O., Ph.D., explores the latest breakthroughs in longevity science - from epigenetic restoration to fasting, exercise, sleep, metabolism, and the emerging technologies that could help us live longer and healthier lives. Drawing on more than 30 years of research and conversations at the frontier of science and medicine, Dr. Sinclair breaks down complex discoveries into practical, evidence-based insights designed to help you understand how the body ages - and what may be possible to slow, optimize, or even reverse aspects of that process. This season features: • New episodes on fasting, exercise, metabolic health, and longevity science • The latest research on biological aging and cellular repair • Practical tools for healthier living backed by scientific evidence • New conversations around the future of medicine and human healthspan We're building the world's largest longevity community, focused on supporting medical research and living longer, together. Join us at https://lifespan.com Follow Lifespan: Instagram: https://instagram.com/lifespan X: https://x.com/JoinLifespan Follow Dr. David Sinclair: Instagram: https://instagram.com/davidsinclairphd Threads: https://threads.net/@davidsinclairphd X: https://x.com/davidasinclair Bluesky: https://bsky.app/profile/davidsinclairphd.bsky.social LinkedIn: https://linkedin.com/in/davidsinclairphd YouTube: https://www.youtube.com/@LifespanOfficial Watch or listen on YouTube, Spotify, and Apple Podcasts.
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    2 mins
  • What To Do For Longevity | Lifespan with Dr. David Sinclair Rewind

    What To Do For Longevity | Lifespan with Dr. David Sinclair Rewind
    May 6 2026
    What are the most important things you can do today to live longer and stay healthier while doing it? In this first Lifespan Rewind episode, Dr. David Sinclair, A.O., Ph.D., a Professor of Genetics for over 25 years at Harvard Medical School and a leader in the field of longevity research, revisits the most impactful insights from his #1-ranked Season 1 series, combining updated commentary with key moments from across all eight episodes. The result is a focused, practical guide to the science of longevity – grounded in evidence and designed for real-world application. This episode covers: What to eat – and what to avoid – for long-term health How to think about exercise for longevity (not just performance) The role of cold and heat exposure Which supplements may support healthy aging Emerging medical interventions and what the science actually shows The tools and protocols Dr. Sinclair personally uses in his own routine Whether you're new to longevity science or looking to refine your approach, this episode brings together the most important principles in one place so you can better understand not just what to do, but why it matters. At Lifespan, our mission is to help you and your loved ones live longer, healthier lives while supporting medical research aimed at breakthroughs to extend all our lives. Join us at: https://lifespan.com. We’re building the world’s largest longevity community who will grow, learn, and live longer together. Subscribe here for new Lifespan show episodes every two weeks. __________________________________________ Partners of the Lifespan show help us keep this program freely available as an educational resource while also supporting medical research. We only collaborate with partners whose products are grounded in strong science – and products our team has personally used for many years. Our selected partners make it convenient for the Lifespan audience to access the tools and technologies featured in this episode – from exogenous fuel for neurons (Ketone-IQ), to wearables that track recovery, strain, and sleep (WHOOP), to smart devices that measure key health metrics such as visceral fat content and muscle gains (Withings). If you’d like to learn more or try these tools: Ketone-IQ: Get 30% off your first monthly order at ketone.com/lifespan with code LIFESPAN WHOOP: Get a free WHOOP band plus one month free at join.whoop.com/LIFESPAN with code LIFESPAN Withings: Explore their smart health devices at withings.com/lifespan using code LIFESPAN __________________________________________ Legal & Medical Disclaimers The Lifespan show and all related content are provided for informational and educational purposes only and are not intended as medical advice, diagnosis, or treatment. Nothing presented should be interpreted as a recommendation to diagnose, treat, cure, or prevent any disease or medical condition. This content is not a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. You should always consult with a licensed physician or other qualified healthcare professional before making decisions about your health, including starting, stopping, or modifying any treatment, supplement, diet, or exercise program. The information shared reflects the views and opinions of the host and guests and is based on the scientific literature, their experience and expertise, and general wellness principles. Listening to or engaging with Lifespan content does not establish a doctor–patient or clinical relationship. Health and longevity outcomes can vary significantly between individuals. Any references to studies, interventions, products, or protocols are not guarantees of specific results, and individual responses may differ. From time to time, Lifespan may discuss or partner with third-party products or services. These references are provided for informational purposes only and should not be considered medical recommendations or endorsements of efficacy for any individual. Lifespan Foundation is an independent 501(c)(3) non-profit organization whose mission is to support medical research. The views expressed by Dr. David Sinclair, A.O., Ph.D., are his own and do not represent those of Harvard University, Harvard Medical School, or any affiliated institutions.
    Show More Show Less
    59 mins
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Startling insights into aging. Skillfully building upon the assertion that aging is as much a disease as Smallpox was, and that aging is treatable and reversible.

Brings alive the science of aging

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