Episodes

  • NEJM This Week — June 25, 2026

    NEJM This Week — June 25, 2026
    Jun 24 2026
    This week, we discuss a promising step toward a functional cure for chronic hepatitis B, first-line pulsed field ablation for persistent atrial fibrillation, reducing the demand for transfusion in surgery, treatment for rifampicin-resistant tuberculosis, and a decade-long look at CAR T-cell therapy outcomes. We review peanut allergy and discuss a case of a man with leg weakness, pain, and weight loss; Perspectives explore GLP-1 access, air-quality policy, and the human realities of homelessness.
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    28 mins
  • NEJM This Week — July 2, 2026

    NEJM This Week — July 2, 2026
    Jul 1 2026
    This week, we discuss less-invasive approaches to guiding coronary intervention, new strategies for preventing kidney cancer recurrence, and head-to-head treatment data in multiple sclerosis. We review advances in multiple sclerosis, follow a diagnostic journey involving gait instability, and discuss correcting false narratives. Perspectives examine physicians and the body politic, chronic pain and OUD, and the often-overlooked burden of cognitive symptoms.
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    24 mins
  • NEJM This Week — July 9, 2026

    NEJM This Week — July 9, 2026
    Jul 8 2026
    This week, we present advances in the treatment of idiopathic pulmonary fibrosis, hypothalamic obesity, and lung cancer. We review nutrition in critical illness and follow a diagnostic case involving a patient who had a lung transplant. The Editors warn about the politicization of science. We discuss the dead donor rule in an era of voluntary euthanasia. Perspectives explore the forthcoming crisis in long-term care, reproductive medicine, and the realities of caring for loved ones at the end of life.
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    25 mins
  • NEJM This Week — July 16, 2026

    NEJM This Week — July 16, 2026
    Jul 15 2026
    This week, we present advances in the treatment of multiple myeloma, systemic lupus erythematosus, and coronary artery disease, alongside new national data on health care–associated infections. We also review fibromyalgia and the emerging Bundibugyo virus outbreak, follow a surprising diagnostic case of alpha-gal syndrome, and explore Perspectives on caring for vulnerable patients, trustworthy health information, pharmacotherapeutic decisions in autism care, and the experience of caring for a parent with dementia.
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    25 mins
  • NEJM This Week — July 30, 2026

    NEJM This Week — July 30, 2026
    Jul 29 2026
    This week, we feature advances that may change care for prostate cancer, multiple myeloma, acute pain, and IgA nephropathy. We review platelet factor 4 disorders and follow a case of persistent nasal ulceration. Perspectives explore medical aid in dying, federal authority in health care, public health and litigation, and the challenge of delivering life-changing news with honesty and compassion.
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    27 mins
  • NEJM This Week — August 6, 2026

    NEJM This Week — August 6, 2026
    Aug 5 2026
    This week, we feature new research on chronic kidney disease, high-risk prostate cancer, peripheral artery disease, and oxygen therapy after cardiac arrest. We review the evaluation and management of syncope, follow a challenging case of immune-related inflammatory illness, and report on Perspectives exploring pandemic preparedness, the Bundibugyo Ebola outbreak, and physician mental health.
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    26 mins
  • NEJM This Week — August 20, 2026

    NEJM This Week — August 20, 2026
    Aug 19 2026
    This week, we feature new research on acute respiratory failure, wheezing in childhood, lung cancer, and obesity. We review myeloproliferative neoplasms and follow a diagnostic case of a patient with myasthenia gravis who developed dyspnea and weakness. Perspectives explore medical marijuana research, AI in clinical care, sexual and gender minority health research, and the Perspectives Editor saying goodbye.
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    25 mins
  • NEJM This Week — June 18, 2026

    NEJM This Week — June 18, 2026
    Jun 17 2026
    This week, we discuss endovascular therapy for post-thrombotic syndrome, new evidence on prehospital blood transfusion strategies in trauma patients, and a trial of cefazolin for Staph. aureus bacteremia. We examine evolving approaches to thyroid cancer and share a case of a man with pancytopenia after heart transplantation. Perspectives explore psychedelic therapy, the convergence of Down syndrome and Alzheimer’s disease, and treating addiction.
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    24 mins