Listeners will also get the lowdown on the Bioconcepts Mastering Pathology Summit, to be held on 25-26th October 2024, where Dr. Schloss will present alongside a star-studded lineup of speakers on critical clinic-relevent topics. The event promises to enrich practitioners’ understanding of pathology, explaining the significance of different cancer tests and how such knowledge can be applied in clinical settings. By attending this summit, participants can expect to gain valuable insights to elevate their practice and provide superior patient care, reinforcing the theme of practitioner knowledge directly benefitting patient outcomes.

Get Your Virtual Tickets Now
https://info.bioconcepts.com.au/pathology-summit/pricing?hsCtaTracking=21d48747-d35c-4e36-9015-b3f4af0b48cc%7C70f6b9a1-f874-47ca-9d96-ea59dc52807c#pricing

URGENT MESSAGE: Denise has generously organised a 20% discount for the first 60 people to purchase her upcoming 28 Day WholeFood Challenge course beginning in January 2024:
Use the code: NatMedPodcast20

We're born with a genetic blueprint, including some variations we may have acquired along the way. These variations, called SNPs (short for Single Nucleotide Polymorphisms), influence certain characteristics of our DNA blueprint to change gene expression. What we now know is that diet can have effects on gene expression leading to powerful effects on our health.
And what better clinician to lead us through how to master your genes using food, than Dr Denise Furness.
Strap in and have the rewind button handy. This is an information-packed podcast!

References
MCM6 - lactose
MCM6 is located upstream from the LCT gene, which produces the enzyme lactase required to digest lactose. MCM6 influences LCT and lactase expression.
PMID: 11788828, PMID: 12915462, PMID: 15114531

HLA-DQ haplotypes - Gluten
Human leukocyte antigen (HLA system) encodes the Major Histocompatibility Complex (MHC). These genes code for antigens (proteins) that help cells recognise self versus non-self. Genetic variations within HLA-DQA1 & HLA-DQB1 are linked to coeliac disease and other autoimmune conditions.
PMID: 30763397, PMID: 29244800

MTHFR Folate
MTHFR converts 5,10-methylenetetrahydrofolate (5,10 methyleneTHF) to 5-methyltetrahydrofolate (5-MTHF). 5-MTHF is needed to convert homocysteine to methionine, therefore MTHFR supports methylation (making SAM) reactions throughout the body.
MTHFR 677 T allele and increased risk for lower folate and higher homocysteine levels PMID: 25788000, 24091066, 7647779, 9545395

APO-E Alzheimer's, Lipids
APOE’s main phenotypes are caused by the combination of two SNPs that combine to form the genotypes/isoforms of ε2, ε3 and ε4 or E2, E3, E4. The E4 allele is associated with higher LDL levels and cardiovascular and neurological complications.
PMID: 25328986, PMID: 11882522

SLC30A8 - zinc transporter
Specific to pancreatic islets and mainly expressed in β-cells that transport zinc from the cytoplasm into insulin secretory vesicles. Allelic variants have been associated with glucose and pro-insulin levels and confer susceptibility to insulin resistance and diabetes mellitus (T2DM).
PMID: 28218639, 17463249, 30936916.

FTO and MC4R - weight and obesity
Fat mass and obesity-associated gene (FTO)
Melanocortin-4-receptor (MC4R)
PMID: 31954858, 19079261, 26888713

Most parents go through a period where their child becomes a picky eater, but some children experience excessive anxiety and severely restrictive eating habits. So much so that their microbiota and hence their entire gut health become markedly impaired.
Moreover, the normal strategies we think would help overcome fear of food might actually compound anxiety towards trying new, healthier foods.
Lisa Moane is consummately credentialed to help children with food-related anxiety.
With 3 children of her own, Lisa weaves together the technical know how with the practicalities of family life to ensure achievable positive outcomes for children.
Lisa holds a B.Hsc in Naturopathy, an Adv Diploma in Nutritional Medicine, a Masters in Food Science, and is also an SOS Feeding Therapist Level 3.
In today's episode, Part 1 of a 2-part series, we'll explore the causes and drivers of "food anxiety". Listen in as we delve into the ways in which healthy eating patterns go awry, and how, through gentle but thoughtful ways, we can help an anxious child overcome aberrant eating behaviours.

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REFS TBC

Hi guys, Bear with me.
Shownotes and synopsis up soon.

In the meantime:
https://www.tabithahealey.com/

https://hcanza.org/

Dementia, including Alzheimer's Disease (AD) is the second leading cause of death for Australians, and has been for several years.

Sadly, research is suggesting that the disease burden of dementia, AD and other conditions of cognitive decline is only going to continue to rise.

So, what can we be doing to safeguard our patient's brain health?

Today's guest is Bec Guild, a naturopath, herbalist and the scientific comms manager from the Australian nootropics supplement company, myBrainCo. In today's episode, Bec takes us through the signs, symptoms and risk factors of declining brain wellbeing. She shares how we can use herbs and nutrients with proven nootropic benefits to support our patient's brain longevity.

Skin conditions can be tricky and frustrating for both patient and practitioner. This is where the skills of Rebecca Hughes shine. Her detective-like approach in her quest to help her patients plus years of clinical practice have given her significant expertise in managing skin conditions.
Today we embark on Part 1 of Atopic Dermatitis, commonly called Eczema, how we can tease the presentation apart from other disorders. We'll discuss where the foundations of natural medicine (ie. the gastrointestinal immune response) is placed in the therapeutic approach, considering the significant stress which patients are in, and delve into some of the best approaches and pitfalls of common therapies.
We can't tell you much now, but this is the herald of something exciting for practitioners in the near future. Also, watch out for Part 2 of Eczema, plus further episodes on how we can help patients with other skin disorders.

REFERENCES:
Etiology of Atopic Dermatitis:
Atopic Dermatitis. Health Topics. Nat Inst Athr Musculoskel Skin Dis.
Stanway A. Atopic Dermatitis. Dermney NZ. 2004 Feb. Updated: Jarret P. 2021 Feb, 2023 May. (Accessed 2023 Sept 24).
Galli E, Cincola B, Carello R, et al. Atopic Dermatitis. Acta Biomed. 2020;91(Suppl 11):e2020011.

Guttate Psoriasis:
Saleh D, Tanner LS. Guttate Psoriasis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. [Updated 2023 Jul 31] (Accessed 2023 Sept 24):

Dermatitis Herpetiformis:
Al-Tameemi A, Elyoussfi S, Coulson I. Dermatitis Herpetiformis. Dermnet NZ. 2023 Mar. (Accessed 3023 Sept 24).

Nutritional Approach to inflammatory skin disorders:
Diotallevi F, Campanati A, Emanuela Martina E, et al. The Role of Nutrition in Immune-Mediated, Inflammatory Skin Disease: A Narrative Review. Nutrients. 2022 Feb; 14(3): 591.
Kanda N, Hoashi T, Saeki H. Nutrition and Atopic Dermatitis. J Nippon Med Sch. 2021 Jun 30;88(3):171-177.
Balić A, Vlašić D, Žužul K, et al. Omega-3 Versus Omega-6 Polyunsaturated Fatty Acids in the Prevention and Treatment of Inflammatory Skin Diseases. Int J Mol Sci. 2020 Jan 23;21(3):741.
Charoenngam N, Holick MF. Immunologic Effects of Vitamin D in Human Health and Disease. Nutrients. 2020 Jul;12(7):2097.

Histamine Intolerance:
Histamine Intolerance (impaired histamine degradation)
Low-Histamine Diet in Atopic Dermatitis
Histamine Intolerance- A Pseudoallergic reaction