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Neurology: Disease Deep Dive

Neurology: Disease Deep Dive

Written by: Practical Neurology
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The field of neurology is vast and complex. This series provides thorough conversations with key expert physicians on neurologic conditions including the evolution of our understanding and treatment of these conditions.2024 Practical Neurology Biological Sciences Science
Episodes
  • Part I: Early Alzheimer Disease Detection with the DAC-SP Blueprint Program: Overview of a Scalable Health System Approach
    Feb 12 2026
    Elyse Perweiler, RN, MPP, Professor, Rowan–Virtua School of Osteopathic Medicine, Stratford, NJ, and Tim MacLeod, PhD, Program Director, Healthcare System Preparedness Program, Davos Alzheimer’s Collaborative (DAC), Toronto, Ontario, Canada, examine how health systems can operationalize early cognitive screening to better prepare patients for specialty evaluation. Learn how standardized workflows, digital cognitive tools, and primary care–neurology collaboration can enhance diagnostic efficiency and access to Alzheimer disease care.
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    18 mins
  • Detecting Multiple Sclerosis Earlier: PRLs and the Evolving McDonald Diagnostic Criteria
    Dec 15 2025
    This episode explores new evidence showing that paramagnetic rim lesions (PRLs) are highly prevalent early in multiple sclerosis (MS) and can differentiate MS from mimics with striking accuracy. Dr. Daniel Ontaneda, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, and Dr. Pascal Sati, Cedars-Sinai Medical Center, Los Angeles, CA, discuss how PRLs, paired with optimized susceptibility-based MRI, are reshaping diagnostic confidence and informing the latest revisions to the McDonald criteria.
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    30 mins
  • Modern Glioma Management: Integrating Molecular Markers and New Targeted Therapies
    Dec 3 2025
    Patrick Y. Wen, MD, Dana-Farber Cancer Institute, Boston, MA, discusses current standards of care for low- and high-grade gliomas, including the importance of comprehensive molecular testing, the World Health Organization classification of tumors of the central nervous system, and newly available therapies.
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    14 mins
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