All content and media by Project 100 is created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice.

****

Professor David Heslop brings a unique perspective to longevity through his expertise in occupational medicine, military service, and biological threat assessment. From developing COVID protocols for the NRL to understanding genetic manipulation in laboratories, Heslop explores the hidden factors shaping our health future.

This conversation covers:
• Gene editing and its potential risks for future generations
• The concerning gap between wealthy and poor in accessing longevity technologies
• Australia's cautious approach to new medical testing versus other countries
• How AI will transform medical practice while protecting patient privacy
• The critical data we're missing despite drowning in health information
• Why living longer might create unexpected economic and social problems

The all-new WHOOP is here — now 7% smaller with 14+ days of battery life. New features like Healthspan show how your daily habits are affecting your rate of aging — and now you can check your blood pressure straight from your wrist. If you’re serious about performance, longevity, and actual progress — this is it. Sign up for a one-month free trial at WHOOP.com — or visit join.whoop.com/mentored for one month off your annual membership fee.

Eight Sleep’s newest generation, Pod 5. isn’t just another bed-frame add-on; it’s a high-tech mattress cover that actively adjusts to your body temperature throughout the night, cooling, warming, and even elevating your body when needed, all based on real-time data. The new Pod 5 introduces for the first time, a hydro-powered blanket system, utilising the same technology as the cover to extend temperature regulation across your entire body, not just the mattress surface. Clinically proven to increase quality sleep by up to one hour each night, it’s basically like having an AI-powered sleep coach, personal thermostat, and advanced health tracker working for you while you rest.

Head on over to eightsleep.com/project100 and use the code PROJECT100 (that’s Project one-zero-zero) and get up to $550 off your very own Pod 5. Trust me, your body will thank you for this investment in better sleep.

See omnystudio.com/listener for privacy information.

All content and media by Project 100 is created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice.

****

Dr. Anastasia Hronis brings unique expertise to addiction psychology, exploring how modern technology is rewiring our brains for dependency.

Her surname literally means "long years" — fitting for a conversation about optimising our relationship with dopamine-driven behaviours for longevity.

We spoke about:

• Understanding addiction versus obsession: the neurological differences
• How dopamine pathways become primed for unhealthy patterns
• Why poker machines and social media apps use identical addiction mechanics
• The critical role of frustration tolerance in building resilience
• Why today's youth face unprecedented challenges to mental wellbeing
• Practical strategies for "prescribed boredom" and digital detox
• The alarming parallels between gambling platforms and social media design

This conversation reveals how our convenience-driven world undermines the very psychological resources we need for a fulfilling, long life. All content is for informational purposes only and is not medical advice.

The all-new WHOOP is here — now 7% smaller with 14+ days of battery life. New features like Healthspan show how your daily habits are affecting your rate of aging — and now you can check your blood pressure straight from your wrist. If you’re serious about performance, longevity, and actual progress — this is it. Sign up for a one-month free trial at WHOOP.com — or visit join.whoop.com/mentored for one month off your annual membership fee.

Eight Sleep’s newest generation, Pod 5. isn’t just another bed-frame add-on; it’s a high-tech mattress cover that actively adjusts to your body temperature throughout the night, cooling, warming, and even elevating your body when needed, all based on real-time data. The new Pod 5 introduces for the first time, a hydro-powered blanket system, utilising the same technology as the cover to extend temperature regulation across your entire body, not just the mattress surface. Clinically proven to increase quality sleep by up to one hour each night, it’s basically like having an AI-powered sleep coach, personal thermostat, and advanced health tracker working for you while you rest.

Head on over to eightsleep.com/project100 and use the code PROJECT100 (that’s Project one-zero-zero) and get up to $550 off your very own Pod 5. Trust me, your body will thank you for this investment in better sleep.

See omnystudio.com/listener for privacy information.

Paul "Hazzo" Haslam brings decades of experience as a clinical exercise physiologist, having trained elite athletes from Olympic medallists to NRL players to cricket legend Brett Lee.

In this comprehensive episode, we dive deep into the science of building and maintaining muscle mass, strength training protocols, and the delicate balance between cardiovascular fitness and muscle preservation as we age. We spoke about:

• The truth about compound exercises and why they're essential for longevity
• How to structure strength training for maximum results without joint damage
• Why bigger muscles actually help control blood sugar and prevent diabetes
• The relationship between VO2 max and brain health, including dementia prevention
• Sarcopenia and how to recognise if you're losing muscle mass
• Nutrition timing and protein requirements for maintaining muscle after 40 • The posterior chain and why your glutes are disappearing with age

The all-new WHOOP is here — now 7% smaller with 14+ days of battery life. New features like Healthspan show how your daily habits are affecting your rate of aging — and now you can check your blood pressure straight from your wrist. If you’re serious about performance, longevity, and actual progress — this is it. Sign up for a one-month free trial at WHOOP.com — or visit join.whoop.com/mentored for one month off your annual membership fee.

Eight Sleep’s newest generation, Pod 5. isn’t just another bed-frame add-on; it’s a high-tech mattress cover that actively adjusts to your body temperature throughout the night, cooling, warming, and even elevating your body when needed, all based on real-time data. The new Pod 5 introduces for the first time, a hydro-powered blanket system, utilising the same technology as the cover to extend temperature regulation across your entire body, not just the mattress surface. Clinically proven to increase quality sleep by up to one hour each night, it’s basically like having an AI-powered sleep coach, personal thermostat, and advanced health tracker working for you while you rest.

Head on over to eightsleep.com/project100 and use the code PROJECT100 (that’s Project one-zero-zero) and get up to $550 off your very own Pod 5. Trust me, your body will thank you for this investment in better sleep.

See omnystudio.com/listener for privacy information.

All content and media by Project 100 is created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice.

****

Dr. Andrei Tutovenau brings dual expertise as both a pharmacist and dentist to reveal the critical connection between oral health and longevity.

Your mouth isn't just about teeth—it's a gateway that can either protect or compromise your entire body's health as you age. We spoke about:
• The surprising link between gum disease and Alzheimer's through chronic inflammation
• Why your mouth is the "dirtiest orifice" and what that means for systemic health
• How poor oral hygiene creates pathways for bacteria to reach your heart and brain
• The diabetes-periodontal disease cycle that feeds on itself
• Daily protocols: proper brushing technique, water picks vs. flossing, tongue scraping
• Acid vs. sugar "insults"—when to brush and when to wait
• Why dry mouth from alcohol and medications accelerates oral health decline.

The all-new WHOOP is here — now 7% smaller with 14+ days of battery life. New features like Healthspan show how your daily habits are affecting your rate of aging — and now you can check your blood pressure straight from your wrist. If you’re serious about performance, longevity, and actual progress — this is it. Sign up for a one-month free trial at WHOOP.com — or visit join.whoop.com/mentored for one month off your annual membership fee.

Eight Sleep’s newest generation, Pod 5. isn’t just another bed-frame add-on; it’s a high-tech mattress cover that actively adjusts to your body temperature throughout the night, cooling, warming, and even elevating your body when needed, all based on real-time data. The new Pod 5 introduces for the first time, a hydro-powered blanket system, utilising the same technology as the cover to extend temperature regulation across your entire body, not just the mattress surface. Clinically proven to increase quality sleep by up to one hour each night, it’s basically like having an AI-powered sleep coach, personal thermostat, and advanced health tracker working for you while you rest.

Head on over to eightsleep.com/project100 and use the code PROJECT100 (that’s Project one-zero-zero) and get up to $550 off your very own Pod 5. Trust me, your body will thank you for this investment in better sleep.

See omnystudio.com/listener for privacy information.

All content and media by Project 100 is created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice.

****

In this episode, Dr. Michael Bonning — former President of the AMA (NSW) — explains why ages 36 to 46 are the most critical decade for your long-term health and longevity.

Backed by longitudinal research and real-world clinical experience, he breaks down how changing your habits around alcohol, nutrition, movement, sleep and social connection during this window can shape your healthspan for decades to come.

If you’re in your late 30s or 40s, this conversation is a wake-up call.

The all-new WHOOP is here — now 7% smaller with 14+ days of battery life. New features like Healthspan show how your daily habits are affecting your rate of aging — and now you can check your blood pressure straight from your wrist. If you’re serious about performance, longevity, and actual progress — this is it. Sign up for a one-month free trial at WHOOP.com — or visit join.whoop.com/mentored for one month off your annual membership fee.

Eight Sleep’s newest generation, Pod 5. isn’t just another bed-frame add-on; it’s a high-tech mattress cover that actively adjusts to your body temperature throughout the night, cooling, warming, and even elevating your body when needed, all based on real-time data. The new Pod 5 introduces for the first time, a hydro-powered blanket system, utilising the same technology as the cover to extend temperature regulation across your entire body, not just the mattress surface. Clinically proven to increase quality sleep by up to one hour each night, it’s basically like having an AI-powered sleep coach, personal thermostat, and advanced health tracker working for you while you rest.

Head on over to eightsleep.com/project100 and use the code PROJECT100 (that’s Project one-zero-zero) and get up to $550 off your very own Pod 5. Trust me, your body will thank you for this investment in better sleep.

See omnystudio.com/listener for privacy information.

In this episode, Mark sits down with Neal Mercado, Chief Science Officer at Melrose, one of Australia’s leading wellness brands.

With a background in pharmaceutical sciences and more than 15 years in product formulation and clinical research, Neal brings rare insight into how supplements are actually developed, tested, regulated, and sometimes compromised.

Neal most recently advised on the creation of FUTURELAB, a product range dedicated to the science of ageing well. Together, they unpack what works, what doesn’t, and what consumers need to know in an industry crowded with noise.

This is a grounded conversation about longevity, metabolic health, and why scientific rigour matters more than ever.

In this episode, we cover:
• How supplement products are formulated and regulated
• The real risks of adulteration and misleading labels
• What a Chief Science Officer actually does
• The science behind berberine and metabolic health
• Why resveratrol remains controversial
• The biggest challenges facing the supplement industry
• How FUTURELAB approaches ageing well differently
• The rise of personalised health and precision medicine
• Where longevity science is heading next

See omnystudio.com/listener for privacy information.

In this episode, Mark sits down with Sue-Ching Yeoh, an AHPRA-registered Oral Medicine Specialist with clinical appointments at Royal Prince Alfred Hospital and Chris O’Brien Lifehouse, and an academic role at the University of Sydney. This conversation goes far beyond dentistry. A/Prof Yeoh explains how the mouth acts as an early warning system for systemic disease, including autoimmune conditions, cancer, HPV, and chronic inflammation. She breaks down what gum disease actually is, why bad breath is often a medical issue rather than a hygiene one, and how lifestyle, genetics, vaping, smoking, and even social media trends are quietly damaging oral health

They also cover practical, no-nonsense advice most people never hear:

• How to properly self-check your mouth

• The truth about tongue cleaning, salt water rinses, whitening, and sensitivity

• What tooth wear says about stress, nerve health, and aging

• When cosmetic treatments help and when they mask deeper problems

• Why early detection in oral health can be life-saving

Eight Sleep’s newest generation, Pod 5. isn’t just another bed-frame add-on; it’s a high-tech mattress cover that actively adjusts to your body temperature throughout the night, cooling, warming, and even elevating your body when needed, all based on real-time data. The new Pod 5 introduces for the first time, a hydro-powered blanket system, utilising the same technology as the cover to extend temperature regulation across your entire body, not just the mattress surface. Clinically proven to increase quality sleep by up to one hour each night, it’s basically like having an AI-powered sleep coach, personal thermostat, and advanced health tracker working for you while you rest.

Head on over to eightsleep.com/project100 and use the code PROJECT100 (that’s Project one-zero-zero) and get up to $550 off your very own Pod 5. Trust me, your body will thank you for this investment in better sleep.

The all-new WHOOP is here — now 7% smaller with 14+ days of battery life. New features like Healthspan show how your daily habits are affecting your rate of aging — and now you can check your blood pressure straight from your wrist. If you’re serious about performance, longevity, and actual progress — this is it. Sign up for a one-month free trial at WHOOP.com — or visit join.whoop.com/mentored for one month off your annual membership fee.

See omnystudio.com/listener for privacy information.

All content and media by Project 100 is created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice.

****

I loved talking to these experts on Project 100 from all around the world, each bringing different backgrounds, experiences and perspectives. Who would you love for me to interview on Project 100 next?

Here are some highlights from the standout episodes of the year:

0:00 – 10:45 — Gary Brecka
10:46 – 24:57 — Jordan Sullivan (Fight Dietitian)
24:58 – 32:06 — Dr Andy Galpin
32:07 – 42:35 — Dr Steven Lu
43:36 – 51:55 — Professor Sarah McKay
51:56 – 1:04:43 — Dr Lila Landowski

See omnystudio.com/listener for privacy information.