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Reason with Science

Reason with Science

Written by: Jitender Kumar
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Welcome to "Reason with Science", the podcast that explores the intersection of reason and science in our everyday lives. Billions of years of evolution led to a species which is asking questions about its own existence. This quest of humans is not possible without science. As we navigate an increasingly complex world, it's more important than ever to approach issues with a clear and evidence-based understanding. In this podcast, we'll dive into the latest research, explore fascinating topics, and interview experts in their respective fields to help us make sense of the world around us.Jitender Kumar Science
Episodes
  • Why evolution explains more than we think
    Dec 12 2025

    Evolution is often misunderstood as a process limited to biology and genes. In this in-depth conversation, evolutionary ecologist Mark Vellend challenges that narrow view and presents a powerful idea: evolution is a universal principle that governs all complex systems.

    In this episode of Reason with Science, we explore how evolution applies not only to living organisms, but also to languages, technologies, cultures, institutions, scientific theories, economics, and artificial intelligence. Drawing on his book Everything Evolves: Why Evolution Explains More Than We Think (From Proteins to Politics), Mark Vellend explains why evolutionary theory deserves recognition as a general science of change, alongside physics.

    We discuss:-

    •What makes a system evolutionary in the most fundamental sense

    • Why Darwinism shaped — and narrowed — our understanding of evolution

    • How languages evolve through everyday use and variation

    • Why technologies advance through trial, error, and selection

    • How cultural norms, ideas, and institutions evolve over time

    • The role of randomness, contingency, and selection beyond biology

    • Evolutionary thinking in AI, economics, and complex systems

    • Tipping points, feedback loops, and irreversible change in ecosystems and societies

    This episode is essential viewing for scientists, students, educators, philosophers, and anyone curious about how the world changes — from cells to civilizations.


    📘 Book discussed: Everything Evolves by Mark Vellend

    🎙️ Podcast: Reason with Science


    Guests info

    Website : https://mvellend.weebly.com/

    Linked in : https://www.linkedin.com/pulse/mark-vellend-everything-evolves-princeton-university-press-is5xc


    Episode links:

    Website: https://reasonwithscience.com/why-evolution-explains-more-than-we-think

    Youtube: https://www.youtube.com/watch?v=yYqQOPph6Qo

    Spotify: https://open.spotify.com/episode/6CQdIDnDABUPMCkgoy4gCL?si=U6zufCa_RMqckOQijL4n1A

    Apple podcast: https://podcasts.apple.com/us/podcast/why-evolution-explains-more-than-we-think/id1641776894?i=1000741038261

    YouTube music: https://music.youtube.com/watch?v=yYqQOPph6Qo&si=gGOJsq0EzY7rldSH


    Follow Reason with Science:

    Website: ⁠⁠⁠⁠https://www.reasonwithscience.com/ ⁠⁠⁠⁠

    Youtube: ⁠⁠⁠⁠https://www.youtube.com/@ReasonwithScience⁠⁠⁠⁠

    Spotify: https://open.spotify.com/show/5qFLGsPWjL4GAGidmF2nKh

    Apple podcast: https://podcasts.apple.com/us/podcast/reason-with-science/id1641776894

    YouTube music: https://music.youtube.com/playlist?list=PLila1Jm-QEwKu4xXtNpYFAsSDmPR9mlZB&si=5ehXeZhZ-z181G5b


    Timestamps:

    00:00:13 — Opening & episode premise: evolution beyond biology00:01:05 — What makes something an evolving system?00:01:46 — Welcome to Mark Vellend00:02:05 — Mark’s research: ecology, climate change, and evolution00:03:17 — Evolution as a universal process00:05:13 — Why evolution goes beyond DNA and genes00:06:45 — Language as an evolving system00:07:45 — Technology, trial-and-error, and innovation00:09:01 — Darwinism and the Modern Synthesis00:11:01 — How biology narrowed the meaning of evolution00:13:03 — The “Second Science”: generalized evolutionary theory00:14:34 — Why direct gene analogies (memes) fail00:17:49 — Modeling evolution without DNA00:20:49 — Selection beyond biology00:51:39 — Tipping points and irreversible change


    #evolution #evolutionexplained #trendingvideo #podcast #biology #culturalevolution #languageevolution #sciencepodcasts #reasonwithscience #philosophyofscience #science #evolutiontheory #sciencetalks #youtubevideo #viralvideo

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    1 hr and 3 mins
  • How sleep shapes the developing Brain with Mark Blumberg I Infant sleep neuroscience I Podcast
    Nov 29 2025

    How sleep shapes the developing Brain with Mark Blumberg This conversation is with Mark Blumberg, a neuroscientist at the University of Iowa whose work has fundamentally reshaped how we understand infant sleep, movement, and early brain development. Mark’s research reveals that sleep is not a passive state, but an active, self-organizing process essential for building the brain’s earliest sensory and motor circuits.We begin by asking a basic yet surprisingly difficult question: What is sleep, really? Mark explains why defining sleep across development and across species is far more complex than it seems, and why the brain during sleep—especially during REM sleep—is often more active than during wakefulness.Together, we explore why infants spend so much of their early life in REM sleep, how sleep unfolds in distinct stages, and why the tiny, jerky movements known as sleep twitches are not meaningless byproducts of dreams, but powerful developmental signals that help wire the brain and body. We discuss how these movements contribute to building internal models of the body, how sleep supports plasticity and learning, and what happens when these processes are disrupted early in life.Finally, we turn to broader questions about development, neurodiversity, and the limits of genetic explanations. Mark argues for the importance of studying typical development in order to understand developmental disorders, and reflects on what infant sleep can teach us about plasticity, embodiment, and the foundations of human cognition.


    Guests info

    Website: https://blumberg.lab.uiowa.edu/

    X: https://x.com/canadiancharity


    Episode links:

    Website: https://reasonwithscience.com/how-sleep-shapes-the-developing-brain-with-mark-blumberg

    Youtube: https://www.youtube.com/watch?v=YNDcpIq2B98

    Spotify: https://open.spotify.com/episode/4ASTAAKKlokphbOc2TJxCi?si=a44044dd89554571

    Apple podcast:

    YouTube music: https://music.youtube.com/watch?v=YNDcpIq2B98&si=Alxad9KU-RtJn78S


    Follow Reason with Science:

    Website: ⁠⁠⁠https://www.reasonwithscience.com/ ⁠⁠⁠

    Youtube: ⁠⁠⁠https://www.youtube.com/@ReasonwithScience⁠⁠⁠

    Spotify: https://open.spotify.com/show/5qFLGsPWjL4GAGidmF2nKh

    Apple podcast: https://podcasts.apple.com/us/podcast/reason-with-science/id1641776894

    YouTube music: https://music.youtube.com/playlist?list=PLila1Jm-QEwKu4xXtNpYFAsSDmPR9mlZB&si=5ehXeZhZ-z181G5b


    Timestamps:

    00:00:00 – Why sleep is one of the greatest unsolved problems in neuroscience

    00:01:22 – What is sleep? Scientific challenges in defining sleep

    00:04:05 – Is sleep a single state or a collection of components?

    00:06:40 – Why sleep is not a passive state: brain activity during REM

    00:08:37 – The major stages of sleep: REM vs non-REM

    00:11:10 – Why dreaming is not the core function of REM sleep

    00:12:22 – How scientists study sleep in humans and animals

    00:15:10 – Sleep deprivation, stress, and experimental limits

    00:19:48 – Why babies sleep so much more than adults

    00:24:10 – The science of twitching during infant sleep

    00:30:05 – How twitches help build the brain’s internal body maps

    00:36:01 – Does twitching continue into adulthood?

    00:43:28 – Learning during sleep vs learning during wake

    00:50:04 – Sleep, memory, and real-world policy implications

    01:21:47 – What infant sleep reveals about development and the future of


    research #reasonwithscience #science #health #lifescience #podcast #sciencepodcasts #trending #trendingvideo #viralvideo

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    1 hr and 24 mins
  • The Metabolic Truth: Rethinking Calories and Energy with Herman Pontzer | Lifestyle | Health | Food
    Oct 18 2025

    This conversation is with Herman Pontzer, an evolutionary anthropologist and professor at Duke University. Herman is best known for his groundbreaking work on human metabolism and energetics, which challenges long-held assumptions about how our bodies burn and manage energy. His field research with hunter-gatherer and subsistence-farming populations—including the Hadza of Tanzania, the Daasanach of Kenya, and the Tsimane’ of Bolivia—has redefined what we know about the relationship between activity, diet, and health.We begin by exploring the deceptively simple question: Why do some people burn more calories than others? Herman explains how the body’s total energy expenditure is remarkably constrained, meaning that even when we exercise more, our bodies often compensate by reducing energy spent elsewhere. This insight challenges the familiar “calories in, calories out” model and reframes how we understand diet, obesity, and modern sedentary lifestyles.Together, we discuss how evolution has shaped the human metabolic system—from the daily life of foragers walking 19,000 steps a day to the physiology of those in industrialized societies. We examine how metabolism interacts with the immune system, reproduction, and brain function, and why understanding these trade-offs is key to improving public health.Herman also shares insights from his books Burn and Adaptable, connecting metabolic research to broader questions about longevity, diet quality, and the future of medicine. Finally, we consider how modern tools—from doubly labeled water to GLP-1 drugs—fit into the long story of how humans manage energy in a changing world.


    Guests info:

    Website: https://sites.duke.edu/pontzerlab/

    X: https://x.com/HermanPontzer


    Episode links:

    Website: https://reasonwithscience.com/the-metabolic-truth-rethinking-calories-and-energy-with-herman-pontzer

    Youtube: https://youtu.be/07qrQN91Iow

    Spotify: https://open.spotify.com/episode/0uN2PJNfEmHckUcdvpg9BJ?si=wZQ4g-ckRnCDNgT71ZwXMg

    Apple podcast: https://podcasts.apple.com/us/podcast/the-metabolic-truth-rethinking-calories-and-energy/id1641776894?i=1000732444106

    YouTube music: https://music.youtube.com/watch?v=07qrQN91Iow&si=Ho8HOtfA5f-Hzzxf


    Follow Reason with Science:

    Website: ⁠⁠https://www.reasonwithscience.com/ ⁠⁠

    Youtube: ⁠⁠https://www.youtube.com/@ReasonwithScience⁠⁠

    Spotify: https://open.spotify.com/show/5qFLGsPWjL4GAGidmF2nKh

    Apple podcast: https://podcasts.apple.com/us/podcast/reason-with-science/id1641776894

    YouTube music: https://music.youtube.com/playlist?list=PLila1Jm-QEwKu4xXtNpYFAsSDmPR9mlZB&si=5ehXeZhZ-z181G5b


    Timestamps:

    00:00:00 — What is metabolism, really?00:01:20 — Who is Herman Pontzer?00:03:10 — Measuring energy in real life00:06:45 — Lessons from the Hadza and Daasanach00:09:30 — The Constrained Energy Expenditure model00:12:15 — Why exercise alone rarely changes body weight00:15:50 — Diet versus activity: the hierarchy of control00:19:10 — Internal trade-offs: the body’s energy budget00:22:35 — Metabolism in global context00:26:20 — Metabolism across the human lifespan00:29:55 — Overtraining, stress, and energy limits00:33:40 — Modern lifestyles and metabolic mismatch00:37:25 — GLP-1 drugs and the new metabolic frontier00:41:10 — Energy, health, and longevity00:45:00 — Evolution’s signature in our metabolism00:48:15 — How culture shapes our energy habits00:52:00 — Metabolism and reproductive health00:56:30 — The science of appetite and satiety01:00:45 — Metabolic research and public health policy01:05:10 — Final reflections on what it means to live energetically#reasonwithscience #science #health

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    1 hr and 16 mins
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