Appraisal of the SHORTCUT and VICTORY trials comparing IVL to CB and OPN balloons plus a bonus interview with Ajay Kirtane MD deconstructing the trials

A critical appraisal of the CREST 2 clinical trial 4-year outcomes comparing carotid revascularization with current medical therapy in asymptomatic patients with high grade carotid artery stenosis.

A critical appraisal of ENCIRCLE and a follow up interview with Encircle Co-PI David Daniels MD make for an interesting episode.

A Critical appraisal of dedicated TAVR valve trials for AI and a general overview of the status of AI treatment in 2025.

A deep dive into bicuspid aortic valve stenosis and the choice of BEV vs SEV- A propensity matched observational study critically appraised.

A deep dive into 2 network metanalysis looking at IVI in contemporary PCI.

A critical appraisal of PLATO (Ticagrelor versus Clopidogrel) and the recent controversies

A decades long practice of routinely tapping effusions upfront in patients with heart failure is challenged with this simple and elegantly conducted clinical trial from Denmark. The TAP IT clinical trial is critically appraised in this month's edition of IC CHAT