In the final part of this series, Mau Sanchez, MBA closes things out with Mauricio Samaniego, CFA and Leon Ramirez by resolving a question left hanging from Part 2: when markets hit all-time highs, do you wait for a pullback or stay invested? Mauricio walks through the real decision he made with client capital, why he chose to stick to the long-term model instead of trying to time a top, and why that decision paid off.

That discipline shows up again in the episode's strongest result: an underweight to technology and an overweight to healthcare, including real names like Eli Lilly and Novo Nordisk, that performed well even during a stretch when the broader healthcare sector struggled. From there, the conversation goes deep on the GLP-1 drug boom (Ozempic and beyond) and why it became a genuine investment thesis.

The back half of the episode turns into a practical explainer on margin and leverage: what it actually is and how margin calls work. The series wraps with closing thoughts on where active management earns its keep, and why discipline (not conviction alone) is what makes a model worth trusting.

In this episode, you'll hear about:

• How to think about staying invested vs. waiting for a pullback at all-time highs
• A real example of an underweight tech, overweight healthcare position paying off
• The investment thesis behind GLP-1 drugs
• What margin and leverage actually are, explained simply
• Where active management adds the most value, and why discipline matters more than conviction

This is Part 3 of a 3-part series on active vs. passive investing.

Chapters:

00:21 Resolving the dry powder decision from Part 2
02:39 Sticking to the model instead of timing the top
04:00 The payoff: underweight tech, overweight healthcare
05:38 Why GLP-1 drugs became a real investment thesis
07:49 The risks nobody's pricing into GLP-1 stocks
09:34 A personal approach to dry powder (not institutional advice)
10:35 Margin and leverage, explained
12:47 Why Portafolio Capital doesn't use leverage for clients
13:12 What margin actually is, and how margin calls work
14:57 A wild story about a forgotten futures contract
16:10 Closing thoughts: where active management earns its edge

Guests:
Mauricio Samaniego, CFA
Leon Ramirez

🎧 Listen on Spotify, Apple Podcasts, and YouTube
🌐 mausanchezpodcast.com

This episode is sponsored by Portafolio Capital Management, an independent, fiduciary investment management firm. Transform your retirement, protect your wealth. visit portafoliocapital.com or call (512) 593-8380 to speak with a financial advisor today.

The opinions and views expressed in this podcast are those of the host and guests speaking in a personal capacity, and do not reflect the views, positions, or decisions of any employer, company, or organization they are affiliated with. Nothing discussed constitutes investment or financial advice and should not be construed as a recommendation to buy or sell any security.

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